The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury by Damien D. Pearse, Francisco C. Pereira, Katina Chatzipanteli, Francisco W. Dalton Dietrich, Mary Bartlett Bunge

“…Injuries to the central nervous system (CNS) usually lead to a potent and acute inflammatory response[1]. …”
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Age-Related Reduced Somatosensory Gating Is Associated with Altered Alpha Frequency Desynchronization by Chia-Hsiung Cheng, Pei-Ying S. Chan, Sylvain Baillet, Yung-Yang Lin

“…Sensory gating (SG), referring to an attenuated neural response to the second identical stimulus, is considered as preattentive processing in the central nervous system to filter redundant sensory inputs. …”
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Microbial alpha diversity in the intestine negatively correlated with disease duration in patients with Meniere’s disease by Fumihiro Mochizuki, Manabu Komori, Jun Shimizu, Yoshiyuki Sasano, Yusuke Ito, Michael E. Hoffer, Yoshishige Miyabe, Izumi Koizuka

“…Recently, gut microbes have been shown to influence the function of the central nervous system in humans through their metabolites. …”
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Therapeutic targeting of obesity-induced neuroinflammation and neurodegeneration by Jialiu Zeng, Jialiu Zeng, Lenny Yi Tong Cheong, Chih Hung Lo, Chih Hung Lo

“…These inflammatory mediators circulate through the bloodstream, propagating inflammation both in the periphery and in the central nervous system. Gut dysbiosis, which results in a leaky intestinal barrier, exacerbates inflammation and plays a significant role in linking obesity to the pathogenesis of neuroinflammation and neurodegeneration through the gut-brain/gut-brain-liver axis. …”
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Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors by Amber N. Edinoff, Connor R. Swinford, Amira S. Odisho, Caroline R. Burroughs, Cain W. Stark, Walid A. Raslan, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye

“…Illicit drugs that stimulate the central nervous system such as ecstasy (MDMA, 3,4-methylenedioxymethamphetamine) act as serotonin releasers. …”
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Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis. by Ali Bigdeli, Mostafa Ghaderi-Zefrehei, Bluma J Lesch, Mehrdad Behmanesh, S Shahriar Arab

“…Multiple sclerosis (MS) is a devastating autoimmune disease that leads to the destruction of the myelin sheath in the human central nervous system (CNS). Infection by viruses and bacteria has been found to be strongly associated with the onset of MS or its severity. …”
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HSV-1 Encephalitis: High Index of Clinical Suspicion, Prompt Diagnosis, and Early Therapeutic Intervention Are the Triptych of Success—Report of Two Cases and Comprehensive Review... by Dimitrios Patoulias, Georgios Gavriiloglou, Konstantinos Kontotasios, Mairi Tzakri, Petros Keryttopoulos, Christos Koutras

“…Herpes Simplex Virus (HSV) encephalitis is an acute infectious disease of the Central Nervous System (CNS), usually affecting the limbic structures, the median temporal cortex, and the orbitofrontal regions. …”
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Glycogen Synthase Kinase 3β Promotes Postoperative Cognitive Dysfunction by Inducing the M1 Polarization and Migration of Microglia by Jingjin Li, Chonglong Shi, Zhengnian Ding, Wenjie Jin

“…Postoperative cognitive dysfunction (POCD) is a common postoperative central nervous system complication, especially in the elderly. …”
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Biofilm Formation of Staphylococcus Aureus in Multiple Sclerosis Patients and its Essential Role in the Pathogenicity of the Disease by Suhad Hassan Aubaid, Ekhlas Saddam Falih, Suhaib khalid Ibrahim

“… Background: Multiple sclerosis (MS) is a chronic inflammatory, autoimmune neurological disease of the central nervous system (CNS). One of the most important factors that lead to increased bacterial resistance to an antibacterial agent and also increase the severity of multiple sclerosis, is the capability of producing enterotoxins and biofilm.    …”
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies by Wouter Claeys, Anja Geerts, Lien Van Hoecke, Christophe Van Steenkiste, Roosmarijn E. Vandenbroucke

“…Recent evidence from animal studies has provided novel insights into old and new downstream effects of astrocyte and microglial dysfunction such as toxin clearance disruption and myeloid cell attraction to the central nervous system parenchyma. Furthermore, state of the art research increasingly implicates neuronal dysfunction and possibly even irreversible neuronal cell death. …”
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Canadian Expert Panel Recommendations on the Management of CNS Symptoms Related to Efavirenz by M John Gill, Anita Rachlis, Sharon Walmsley, Mark Halman, The Efavirenz Consensus Working Group

“…The present report outlines general management recommendations that apply to adverse effects related to efavirenz initiation, as well as specific management strategies for central nervous system symptoms such as agitation, sleep disturbances, dreams, dizziness, impaired concentration and depression. …”
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Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

“…Neuroinflammation is a complex and dynamic response of the central nervous system (CNS) to injury, infection, and disease. …”
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Follow-Up of Newborns with Neural Tube Defects: A Single Center Experience by Umit Ayse Tandircioglu, Cansu Kethuda Ensert Cihan, Hasan Tolga Celik, Burcak Bilginer, Sule Yigit

“… OBJECTIVES: Neural tube defects, defined as the developmental malformations of the central nervous system, are seen in our country at a rate of three per thousand on average. …”
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The Etiological Spectrum of Febrile Encephalopathy in Adult Patients: A Cross-Sectional Study from a Developing Country by Elham Peidaee, Fereshte Sheybani, HamidReza Naderi, Nasrin Khosravi, Mehdi Jabbari Nooghabi

“…The most common diagnosis in patients with clinical syndromes suggestive of central nervous system (CNS) infection was sepsis associated encephalopathy (SAE) (22.9%), followed by bacterial meningitis (14%) and neurotuberculosis (9.9%). …”
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Hepatitis C Virus Infection and Mixed Cryoglobulinemia by Gianfranco Lauletta, Sabino Russi, Vincenza Conteduca, Loredana Sansonno

“…Among them, complement factors play a crucial role in the cold-insoluble ICs-mediated vasculitis, involving primarily small blood vessels in different tissues including skin, kidney, peripheral, and central nervous system. Liver represents the major target of HCV infection with inflammatory infiltrates, resembling secondary lymphoid follicles. …”
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Prion Diseases and the Gastrointestinal Tract by Gwynivere A Davies, Adam R Bryant, John D Reynolds, Frank R Jirik, Keith A Sharkey

“…They are uniformly fatal neurological diseases, which are characterized by ataxia and vacuolation in the central nervous system. Alhough they are known to be caused by the conversion of normal cellular prion protein to its infectious conformational isoform (PrPsc) the process by which this isoform is propagated and transported to the brain remains poorly understood. …”
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Lack of Association between Toxocara Exposure and Suicide Attempts in Psychiatric Patients by Cosme Alvarado-Esquivel, Jesús Hernández-Tinoco, Luis Francisco Sánchez-Anguiano

“…Infection with Toxocara may affect the central nervous system. A high seroprevalence of Toxocara infection has been reported in psychiatric patients. …”
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Hybrid deep learning approach for brain tumor classification using EfficientNetB0 and novel quantum genetic algorithm by Kerem Gencer, Gülcan Gencer

“…One of the most complex and life-threatening pathologies of the central nervous system is brain tumors. Correct diagnosis of these tumors plays an important role in determining the treatment plans of patients. …”
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Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace by Tingting Zhou, Xuannan Chen, Yu Lai

“…The hotspots in this field are “neurocognitive impairment,” “central nervous system,” “cerebrospinal fluid,” “HIV-1 tat,” “SIV,” “inflammation,” “infection,” and “pathogenesis.” …”
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Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin by Fang Zhang, Luyi Wu, Jimeng Zhao, Tingting Lv, Zhihai Hu, Zhijun Weng, Shuoshuo Wang, Huangan Wu, Huirong Liu

“…The generation of pain involves a series of processes, including energy transduction of stimulatory signals in the sensory nerve endings (signal transduction), subsequent conduction in primary afferent nerve fibers of dorsal root ganglia, and transmission to spinal dorsal horn neurons, the ascending transmission of sensory signals in the central nervous system, and the processing of sensory signals in the cerebral cortex. …”
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