Germinoma in the Internal Auditory Canal Mimicking a Vestibular Schwannoma by Rubén Martín-Hernández, Diego Hernando Macías-Rodríguez, Ángel Muñoz-Herrera, Juan Carlos Del Pozo-de Dios, Santiago Santa Cruz-Ruiz, Ángel Batuecas-Caletrío

“…The appearance of a primary germinoma in the central nervous system but not on or near the midline or within the brain is exceptional. …”
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PPARγ in Bacterial Infections: A Friend or Foe? by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Its immunoregulatory function has been studied in a variety of contexts, including bacterial infections of the lungs and central nervous system, sepsis, and conditions such as chronic granulomatous disease. …”
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Amebic Encephalitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy by Ensi Voshtina, Huiya Huang, Renju Raj, Ehab Atallah

“…In this report, we present a patient with CLL on ibrutinib therapy who developed rapidly declining neurological status concerning for the central nervous system (CNS) process related to his immunocompromised status. …”
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Targeting glycolysis: exploring a new frontier in glioblastoma therapy by Lu Yang, Sijia Li, Lei Yu, Jiao Leng, Na Li

“…Glioblastoma(GBM) is a highly malignant primary central nervous system tumor that poses a significant threat to patient survival due to its treatment resistance and rapid recurrence.Current treatment options, including maximal safe surgical resection, radiotherapy, and temozolomide (TMZ) chemotherapy, have limited efficacy.In recent years, the role of glycolytic metabolic reprogramming in GBM has garnered increasing attention. …”
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Major congenital defects. Relevant risk factors. Cienfuegos. 2000-2005. by Vivian Vázquez Martínez, Cristóbal Torres González, Gabriel González Jiménez, Yobadis Hernández del Sol, Ana López Rodríguez del Rey, Gladis Barberis Pérez

“…<strong><br />Results:</strong> There was a predominance of Central Nervous System defects (28, 6%). The most relevant risk factors were a history of congenital defects, smoking habits, and acute infection during the first three months, as well as belong to the third birth on. …”
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Relationship between Zinc (Zn2+) and Glutamate Receptors in the Processes Underlying Neurodegeneration by Bartłomiej Pochwat, Gabriel Nowak, Bernadeta Szewczyk

“…This review describes the relationship between Zn2+ and glutamate dependent signaling pathways under selected pathological central nervous system (CNS) conditions.…”
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Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders by Yasir Qasim Almajidi, Rana Kadum Muslim, Yaseen T. khalf

“…However, the delivery of nucleic acids to the central nervous system (CNS) by the systemic route, remains a major hurdle. …”
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Heberferón®’s economic feasibility in patients with high-grade brain tumors without therapeutic options by María Margarita Ríos Cabrera, Iraldo Bello Rivero, Javier Cruz Rodríguez

“…<p><strong>Foundation:</strong> neoplastic diseases in general and particularly those of the central nervous system constitute health problems that negatively impact personal, family and society life. …”
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Infant of a diabetic mother: clinical presentation, diagnosis and treatment by Magdalena Suda-Całus, Katarzyna Dąbrowska, Ewa Gulczyńska

“…Infants of diabetic mothers (IDMs) because of mother’s diabetes are prone to developing complications and the most common include: large birth weight and complications resulting from it (i.e. birth injuries, perinatal asphyxia), cardiovascular and respiratory insufficiency (poor tolerance of labor stress), neonatal hypoglycemia and it’s complications, delayed lung maturity (fetal hyperinsulinism and the opposite function of insulin to cortisol), cardiomegaly and hypertrophy of the intraventricular septum (functional narrowing of the outflow of the left ventricle and cardiac failure), congenital malformations (most often of the central nervous system and heart). Less common complications in IDMs are: persistent pulmonary hypertension, hyperbilirubinemia, renal vein thrombosis, small left colon syndrome, intrauterine death, polycythemia, and a predisposition to obesity, insulin resistance and diabetes later in life. …”
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Nerve Blockage Attenuates Postoperative Inflammation in Hippocampus of Young Rat Model with Surgical Trauma by Yi He, Zhi Li, Yun-Xia Zuo

“…It is hypothesized that central nervous system inflammation induced by systematic inflammation due to surgical trauma plays a critical role in postoperative cognitive dysfunction. …”
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PPARs in Human Neuroepithelial Tumors: PPAR Ligands as Anticancer Therapies for the Most Common Human Neuroepithelial Tumors by Elisabetta Benedetti, Renato Galzio, Barbara D'Angelo, Maria Paola Cerù, Annamaria Cimini

“…The incidence of central nervous system neoplasms ranges from 3.8 to 5.1 cases per 100,000 in the population. …”
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Improved Set-point Tracking Control of an Unmanned Aerodynamic MIMO System Using Hybrid Neural Networks by Oduetse Matsebe, David Mohammed Ezekiel, Ravi Samikannu

“…Artificial neural networks (ANN), an Artificial Intelligence (AI) technique, are both bio-inspired and nature-inspired models that mimic the operations of the human brain and the central nervous system that is capable of learning. This paper is based on a system that optimizes the performance of an uncertain unmanned nonlinear Multi-Input Multi-Output (MIMO) aerodynamic plant called Twin Rotor MIMO System (TRMS). …”
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Synaptic Wnt/GSK3β Signaling Hub in Autism by Mario O. Caracci, Miguel E. Ávila, Giancarlo V. De Ferrari

“…The Wnt/β-catenin signaling pathway plays a central role in the development and regulation of the central nervous system and several genes belonging to the cascade have been genetically associated with ASDs. …”
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Two Atypical Cases of Hantavirus Infections from Sri Lanka by N. D. B. Ehelepola, B. M. L. S. Basnayake, S. M. B. Y. Sathkumara, K. L. R. Kaluphana

“…They had clinical pictures of a combination of both HFRS and HPS as well as the involvement of the central nervous system. Hantavirus infections are rarely diagnosed in South Asia. …”
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Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2 by Junqi Fu, Jun Peng, Guolong Tu

“…Glioma is a malignant tumor that often occurs in the adult central nervous system. Metadherin/astrocyte-elevated gene-1 (MTDH) is involved in the development of cancer, but its relationship with glioma remains unclear. …”
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Rapid and simple determination of histamine-N-methyl transferase activity by high-performance liquid chromatography with UV detection by Hajime Inoue, Ken-Ichi Hisamatsu, Miki Yamauchi, Norio Kumagai

“…Therefore, the present method could be applicable for the enzymatic investigation of histamine metabolism in central nervous system or inflammatory reactions.…”
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The immunological perspective of major depressive disorder: unveiling the interactions between central and peripheral immune mechanisms by Wenli Jiao, Jiayi Lin, Yanfang Deng, Yelin Ji, Chuoyi Liang, Sijia Wei, Xi Jing, Fengxia Yan

“…Peripherally, systemic inflammation, gut immune dysregulation, and immune dysfunction in organs including gut, liver, spleen and adipose tissue influence brain function through neural and molecular pathways. Within the central nervous system, aberrant microglial and astrocytes activation, cytokine imbalances, and compromised blood-brain barrier integrity propagate neuroinflammation, disrupting neurotransmission, impairing neuroplasticity, and promoting neuronal injury. …”
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Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy by Natsuyo Yoshida-Hata, Shigeko Yashiro, Noritoshi Arai, Sousuke Takeuchi

“…We recommend that steroid pulse therapy be considered to treat patients with sarcoidosis with signs of lesions in the central nervous system.…”
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Late Relapse of Previous Pulmonary Cryptococcosis With Symptoms Resembling Cerebral Infarction: A Case Report by Anatoli Pinchuk, Gernot Geginat, Volker Rickerts, Belal Neyazi, Klaus Peter Stein, Christian Mawrin, I. Erol Sandalcioglu, Ali Rashidi

“…Cryptococcosis, an infection caused by Cryptococcus neoformans and Cryptococcus gattii, predominantly targets the central nervous system (CNS) in patients with AIDS but is not limited to this group. …”
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Baller-Gerold Syndrome. About a Clinical Case and Review of the Literature by Anolys Narciso Piña Rodríguez, Osiris Intento García, Sady Montes Amador

“…She was given parenteral feeding for several days, it was impossible to establish an adequate oral route due to the absence and/or incoordination of the sucking-swallowing reflexes as an expression of her malformations at the central nervous system level. The case is presented due to its low incidence and prevalence, which is why it is considered a rare disease.…”
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