CoTF-reg reveals cooperative transcription factors in oligodendrocyte gene regulation using single-cell multi-omics by Jerome J. Choi, John Svaren, Daifeng Wang

“…Abstract Oligodendrocytes are the myelinating cells within the central nervous system, but the mechanisms by which transcription factors (TFs) cooperate for gene regulation in oligodendrocytes remain unclear. …”
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Peripheral Mechanisms of Symptom Generation in Irritable Bowel Syndrome by Stephen M Collins

“…There is considerable interest in the mechanisms that underlie symptom generation in irritable bowel syndrome (IBS) and particularly those mechanisms peripheral to higher centres in the nervous system. While the central nervous system is important in IBS, it is restricted largely to the role of behaviour in stress perception and symptom reporting. …”
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Methamphetamine Use: A Narrative Review of Adverse Effects and Related Toxicities by Amber N. Edinoff, Sarah E. Kaufman, Keionne M. Green, Daniel A. Provenzano, Jesse Lawson, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye

“…Methamphetamine-related myocardial infarction can also occur. Central nervous system symptoms include agitation, anxiety, delusions, hallucinations, and seizures. …”
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Roles of Mesenchymal Stem Cells in Spinal Cord Injury by Jing Qu, Huanxiang Zhang

“…Spinal cord injury (SCI) represents one of the most complicated and heterogeneous pathological processes of central nervous system (CNS) impairments, which is still beyond functional regeneration. …”
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Cholecystokinin facilitates the formation of long-term heterosynaptic plasticity in the distal subiculum by Fengwen Huang, Abdul Baset, Stephen Temitayo Bello, Xi Chen, Jufang He

“…Cholecystokinin (CCK), is the most abundant neuropeptide in the central nervous system, which broadly regulates the animal’s physiological status at multiple levels, including neuroplasticity and its behavioral consequences. …”
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Spinal Cord Injury and Bladder Dysfunction: New Ideas about an Old Problem by Célia Duarte Cruz, Francisco Cruz

“…Control of the lower urinary tract (LUT) requires complex neuronal circuits that involve elements located at the peripheral nervous system and at different levels of the central nervous system. Spinal cord injury (SCI) interrupts these neuronal circuits and jeopardizes the voluntary control of bladder function. …”
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Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy by Zhuangzhuang Zhang, Jianwen Deng, Weiping Sun, Zhaoxia Wang

“…ABSTRACT Introduction Cerebral cavernous malformation (CCM) is a type of cerebrovascular abnormality in the central nervous system linked to both germline and somatic genetic mutations. …”
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Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses by Elek Molnar, John T.R. Isaac

“…Glutamate receptors mediate the majority of excitatory responses in the central nervous system. The establishment and refinement of glutamatergic synaptic connections depend on the concerted actions of a-amino-3-hydroxy-5-methyl-isoxazole-4-propionate (AMPA), N-methyl-D-aspartate (NMDA), and kainate (KA) type ionotropic glutamate receptors (iGluRs) and G-protein coupled metabotropic receptors. …”
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Astrocytic heterogeneous nuclear ribonucleoprotein U is involved in scar formation after spinal cord injury by Lili Quan, Akiko Uyeda, Ichiro Manabe, Rieko Muramatsu

“…Abstract Astrocytes have a beneficial role in tissue repair after central nervous system (CNS) injury. Although astrocyte proliferation is activated in response to injury, the intracellular mechanisms of astrocyte proliferation during acute phase of injury are not fully clarified. …”
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Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal by Ahmet Bulent Yazici, Esra Yazici, Atila Erol

“…Effects of SCs on the central nervous system are similar to other cannabinoids, but 2–100 times more potent than marijuana. …”
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In Vivo Optical Imaging of Neurogenesis: Watching New Neurons in the Intact Brain by Sebastien Couillard-Despres, Rudolf Finkl, Beate Winner, Sonja Ploetz, Dirk Wiedermann, Robert Aigner, Ulrich Bogdahn, Juergen Winkler, Mathias Hoehn, Ludwig Aigner

“…Indeed, the DCX-promo-luciferase mice allowed optical in vivo imaging of the onset of and increase in neurogenesis in developing fetal brains, as well as imaging of neurogenesis in the intact adult mouse central nervous system. Moreover, the capacity to specifically detect a small number of migrating neuronal precursors in vivo after transplantation is for the first time feasible using this DCX-promo-luciferase transgenic tool. …”
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Microglia and Spinal Cord Synaptic Plasticity in Persistent Pain by Sarah Taves, Temugin Berta, Gang Chen, Ru-Rong Ji

“…Microglia are regarded as macrophages in the central nervous system (CNS) and play an important role in neuroinflammation in the CNS. …”
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Presumed Sturge Weber Syndrome in a Haitian Boy: A Case of Delayed Diagnosis by Gian Paolo Giuliari, Ama Sadaka, Maria Angelica Cortez, Adalgisa Corona

“…SWS presents with hamartomatous malformations and venous dilation affecting the skin, central nervous system and eye. The ocular involvement may vary, with the most common complications being glaucoma, buphthalmos and diffuse choroidal hemangiomas. …”
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Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls by Jacob N Ablin, Natalia Aronov, Ilan Shimon, Hannah Kanety, Clara Pariente, Valerie Aloush, Ori Elkayam, David Levartovsky

“…The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception.…”
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A Giant Gastroschisis Associated with Pulmonary Hypoplasia and Spinal Anomaly: A Case Report and a Literature Review by Surasak Puvabanditsin, Robin Burger, Vidya Puthenpura, Lauren Walzer, Adaora Madubuko, Christine Minerowicz, Rajeev Mehta

“…Most commonly, the anomalies associated with gastroschisis are cardiac and central nervous system abnormalities. Respiratory insufficiency has sometimes been reported in association with giant abdominal wall defects. …”
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Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease by Emma V. Jones, David S. Bouvier

“…Despite being well described in the context of nonneuronal tissues, recent studies have revealed that these molecules may also play instrumental roles in central nervous system (CNS) development and diseases. In this minireview, we discuss the matricellular protein families SPARC (secreted protein acidic and rich in cysteine), Hevin/SC1 (SPARC-like 1), TN-C (Tenascin C), TSP (Thrombospondin), and CCN (CYR61/CTGF/NOV), which are secreted by astrocytes during development. …”
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State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research by Anna-Sophia Wahl

“…Research of recent years has shown the tremendous potential of the central nervous system to react to noxious stimuli such as a stroke: Increased plastic changes leading to reorganization in form of neuronal rewiring, neurogenesis, and synaptogenesis, accompanied by transcriptional and translational turnover in the affected cells, have been described both clinically and in experimental stroke research. …”
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Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse by Bianca P. Campagnaro, Agata L. Gava, Silvana S. Meyrelles, Elisardo C. Vasquez

“…Finally, we highlight the relationships between angiotensin and peripheral and central nervous system areas of cardiovascular control and oxidative stress in the 2K1C hypertensive mouse.…”
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Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases by Luana de Mendonça Oliveira, Franciane Mouradian Emidio Teixeira, Maria Notomi Sato

“…Although vitamin A is crucial for maintaining homeostasis at the intestinal barrier and equilibrating immunity and tolerance, including gut dysbiosis, retinoids perform a wide variety of functions in many settings, such as the central nervous system, skin aging, allergic airway diseases, cancer prevention and therapy, and metabolic diseases. …”
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Nephrological problems in a child with Aicardi-Goutières syndrome by Małgorzata Piejak, Zuzanna Hus, Adam Bujanowicz, Piotr Skrzypczyk, Joanna Samotyjek, Beata Jurkiewicz, Hanna Szymanik-Grzelak, Mariusz I. Furmanek, Małgorzata Pańczyk-Tomaszewska

“…Aicardi-Goutières syndrome (AGS) is a rare genetic disorder characterized by excessive interferon-alpha production, leading to central nervous system damage, manifesting as subacute encephalopathy in infancy. …”
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