EZH2 Regulates Lipopolysaccharide-Induced Periodontal Ligament Stem Cell Proliferation and Osteogenesis through TLR4/MyD88/NF-κB Pathway by Pengcheng Wang, Huan Tian, Zheng Zhang, Zuomin Wang

“…Targeting EZH2 prevented LPS-induced upregulation of the inflammatory cytokines and inhibition of cell proliferation and migration. Furthermore, EZH2 knockdown attenuated the TLR4/MyD88/NF-κB signaling to facilitate PDLSC osteogenesis. …”
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Matrine Inhibits Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition Through Regulating the LINC01116/miR-9-5p/ITGB1 Axis by Lili Ren, Ziru Fang, Jiaojiao Xu, Xiaoxiao Wu, Yongjun Zhang, Hu Cai, Zhicun Han

“…However, its mechanism of action, particularly whether it involves the control of cell proliferation and epithelial-mesenchymal transition (EMT), remains unknown. …”
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Mechanisms Involved in the Enhanced Susceptibility of Senescent Rats to the Hepatocarcinogenic Effect of Peroxisome Proliferators: Role of Peroxisome Proliferator-Activated Receptor alpha (PPAR), Cell Proliferation and Oxidative Stress by Jihan A. Youssef, Pierre Ammann, Burhan L. Ghanayem, Linda S. Birnbaum, Mostafa Z. Badr

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SLC35A2 is a novel prognostic biomarker and promotes cell proliferation and metastasis via Wnt/β-catenin/EMT signaling pathway in breast cancer by Rushu Yan, Tianwen Chen

“…Different BC cell lines were used in experiments, and the roles of SLC35A2 in cell proliferation, invasion, and migration was assessed through gene silencing and functional assays. …”
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A novel 4-(1,3,4-thiadiazole-2-ylthio)pyrimidine derivative inhibits cell proliferation by suppressing the MEK/ERK signaling pathway in colorectal cancer by Li Weiwei, Yang Zhifu, Ding Likun, Wang Ying, Zhao Xian, Chu Jian Jie, Ji Qing, Yao Minna, Wang Jingwen

“…The results revealed that compound 4 significantly inhibited HCT116 cell proliferation with IC50 values of 8.04 ± 0.94 µmol L–1 after 48 h and 5.52 ± 0.42 µmol L–1 after 72 h, respectively. …”
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Ethanol Extracts of Solanum lyratum Thunb Regulate Ovarian Cancer Cell Proliferation, Apoptosis, and Epithelial-to-Mesenchymal Transition (EMT) via the ROS-Mediated p53 Pathway by Chen Zhang, Zheming Li, Jie Wang, Xuelu Jiang, Mengting Xia, Jianfen Wang, Shenyi Lu, Shouye Li, Hanmei Wang

“…Flow cytometric and western blot analysis revealed that SLT effectively suppressed ovarian cancer cell proliferation via inducing cell cycle arrest and increasing apoptosis. …”
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Withdrawn: Long non-coding RNA SNHG1 promotes cell proliferation and invasion of hepatocellular carcinoma by acting as a molecular sponge to modulate miR-195 by Shuai Zhang, Xiaoding Song

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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells by Hongde Li, Pengfei Rong, Xiaoqian Ma, Wei Nie, Yan Chen, Juan Zhang, Qiong Dong, Min Yang, Wei Wang

“…Next, mesangial cells were exposed to 5.6 mM glucose, 30 mM glucose, or mUC-MSC-conditioned medium, and then we performed western blotting, immunofluorescence, wound healing assay, and cell proliferation assay to measure extracellular matrix (ECM) proteins and matrix metalloproteinases (MMPs), myofibroblast transdifferentiation (MFT), and cell proliferation. …”
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Long noncoding RNA Gm4419 promotes mesangial cell proliferation and extracellular matrix accumulation via the miR-455-3p/histone deacetylase 2 axis by Yang Wen, Hua Gan, Qing Zhong, Ying Gong

“…Gene silencing of Gm4419 inhibited mesangial cells proliferation and extracellular matrix accumulation. …”
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Effects of Human Alpha-Synuclein A53T-A30P Mutations on SVZ and Local Olfactory Bulb Cell Proliferation in a Transgenic Rat Model of Parkinson Disease by Faustine Lelan, Cécile Boyer, Reynald Thinard, Séverine Rémy, Claire Usal, Laurent Tesson, Ignacio Anegon, Isabelle Neveu, Philippe Damier, Philippe Naveilhan, Laurent Lescaudron

“…A significant increase in resident cell proliferation in the glomerular but not in the granular layers of the OB and in the SVZ was observed. …”
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Cyclosporin, Tacrolimus, Mycophenolic Acid, and Dexamethasone Suppress Peripheral Blood Mononuclear Cell Proliferation and Inhibit Interferon-Gamma, IL-10 and IL-13 Production <em>In Vitro</em> by Abdel-Rahman Youssef

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GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites by Zhihua Sun, Peiyi Li, Xiao Wang, Shuchang Lai, Hong Qiu, Zhi Chen, Shidi Hu, Jie Yao, Jie Shen

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Promotive effect of cancer-testis antigen CT57 on proliferation, invasion, migration and epithelial-mesenchymal transition of liver cancer cells by LUO Lange, ZHENG Chao, LEI Ming

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Kindlin-1 promotes gastric cancer cell motility through the Wnt/β-catenin signaling pathway by Jun-Ho Jang, Jiyoon Jung, Hyeon-Gu Kang, Woong Kim, Won-Jin Kim, Hana Lee, Ju Yeon Cho, Ran Hong, Jeong Won Kim, Joon-Yong Chung, Kyung-Hee Chun, Seok-Jun Kim

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Inhibitory effects of limonin on the proliferation of non-small cell lung cancer cells via targeting S-phase kinase-associated protein 2 by Zhu Jiaxian, Zhang Mengting, Li Shengqing, Liu Yongqiang

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PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

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Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration by Mikel Sánchez, Jon Mercader Ruiz, Daniel Marijuán Pinel, Pello Sánchez, Nicolás Fiz, Jorge Guadilla, Juan Azofra, Maider Beitia, Diego Delgado

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miR-134-3p Regulates Cell Proliferation and Apoptosis by Targeting INHBA via Inhibiting the TGF-β/PI3K/AKT Pathway in Sheep Granulosa Cells by Xinai Huang, Yongjin Bao, Fan Yang, Xiaodan Li, Feng Wang, Chunxiang Zhang

“…Overall, the outcomes of transfections with <i>INHBA</i> and miR-134-3p showed that, in sheep GCs, miR-134-3p targets <i>INHBA</i> to control cell proliferation and apoptosis. In summary, these results add to our understanding of the molecular mechanisms involving important miRNAs in ewe fecundity by indicating that miR-134-3p influences cell proliferation, cell apoptosis, and the TGF-β/PI3K/AKT/mTOR axis, which, in turn, influences the follicular development of sheep GCs.…”
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Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Alveolar Type II Cell Proliferation and Attenuate Lung Inflammation in a Rat Model of Bronchopulmonary Dysplasia by Ou Zhou, Jingyi You, Xiaochuan Xu, Jiang Liu, Huijun Qiu, Chang Hao, Wenjing Zou, Wenjie Wu, Zhou Fu, Daiyin Tian, Lin Zou

“…Taken together, this study suggests MVs derived from hUCMSCs improve lung architecture and function in an antenatal LPS-induced BPD rat model by promoting AT2 cell proliferation and attenuating lung inflammation; thus, MVs provide a promising therapeutic vehicle for BPD treatment.…”
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Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell Proliferation by Activating the PI3K/AKT Signaling Pathway in a Rat Model of Asthma by Min Gao, Qinran Sun, Qingfa Liu

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