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921
Myo-inositol increases respiratory burst, cellular proliferation, and phagocytosis of cultured leukocytes from Nile tilapia
Published 2025-06-01“…Primary cell cultures of head-kidney leukocytes were used to evaluate respiratory burst, cell proliferation, and phagocytosis. Five concentrations of MI were supplemented to the culture media: 0, 300, 600, 900, and 1200 mg l-1 with 16 replicates per concentration. …”
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922
Gamma-Tocotrienol Stimulates the Proliferation, Differentiation, and Mineralization in Osteoblastic MC3T3-E1 Cells
Published 2018-01-01“…Our results showed that γ-tocotrienol (2–8 μmol/L) significantly improved the cell proliferation (p<0.05), but it did not affect cell cycle progression. γ-Tocotrienol significantly increased alkaline phosphatase (ALP) activity (p<0.05), secretion levels of osteocalcin (OC) and osteonectin (ON), and mRNA levels of collagen type I (Col I) of MC3T3-E1 cells. …”
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923
The Role of Inflammatory Cytokines and lncRNAs in the Pathogenesis of Atherosclerosis and Other Inflammatory Diseases: Focus on Sarcoidosis and Alzheimer’s Disease
Published 2025-01-01“…Concurrently, lncRNAs regulate gene expression through transcriptional and post-transcriptional mechanisms, influencing cellular processes such as macrophage polarization and smooth muscle cell proliferation. Beyond atherosclerosis, these mediators are implicated in the pathogenesis of other inflammatory diseases, including sarcoidosis and Alzheimer's disease. …”
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924
TNRC6C Functions as a Tumor Suppressor and Is Frequently Downregulated in Papillary Thyroid Cancer
Published 2021-01-01“…Immunohistochemical assay was performed to detect the protein expression of TNRC6C in PTC and its adjacent noncancerous tissue. Cell proliferation, migration, invasion, and apoptosis were analyzed after knockdown or overexpression of TNRC6C in BCPAP cells. …”
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925
Experimental investigation on the reverse mechano-electrical effect of porcine articular cartilage
Published 2025-02-01“…This may provide valuable insights for further investigation into the microscopic mechanisms of cell proliferation, differentiation, and cartilage regeneration induced by electrical stimulation.…”
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926
Electrochemical properties of hydroxyapatite immobilization material for potential cytosensor fabrication
Published 2023-09-01“…The findings indicate that SHAp/PEDOT: PSS enables the differentiation of cell proliferation signals through voltammetric and impedimetric measurements. …”
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927
Transcriptomic analysis of Medicago truncatula calli with MtWOX9-1 overexpression
Published 2019-10-01“…Different WOX genes function in different plant organs and tissues, maintaining meristem activity and regulating cell proliferation and differentiation. Recently, we have shown that transcription factor MtWOX9-1, belonging to the WOX family, can stimulate SE in the Medicago truncatula callus culture. …”
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928
Multi-omic and machine learning analysis of mitochondrial RNA modification genes in lung adenocarcinoma for prognostic and therapeutic implications
Published 2025-03-01“…Experimental validation identified ALG3 as an oncogenic driver in LUAD, influencing tumor cell proliferation, migration, and invasion. In conclusion, this study establishes MRMS as a robust prognostic biomarker and highlights its dual role in shaping the tumor immune microenvironment and guiding therapeutic strategies. …”
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929
Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence
Published 2024-12-01“…Ki67 is an important biomarker of cell proliferation. With the quantitative analysis, it is an important indicator of malignancy for breast cancer diagnosis. …”
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930
Bilosomal Co-Encapsulated Tamoxifen and Propranolol for Potentiated Anti-Breast Cancer Efficacy: In Vitro and In Vivo Investigation
Published 2025-01-01“…Histopathological investigations reflected a significant decline in tumor giant cells and mitotic figures, implying the in vivo capability of the TAM/PRO combination to interfere with cancer cell proliferation and persistence. <b>Conclusions</b>: The overall results demonstrated the impact of repurposed PRO to enhance the anti-breast cancer activity of TAM when both were co-encapsulated into bilosomes.…”
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931
Dysbiosis and extraintestinal cancers
Published 2025-02-01“…The oncogenic cascade always engages in the disruption of hormonal regulation and inflammatory responses, the induction of genomic instability and mutations, and the dysregulation of adult stem cell proliferation. This review aims to comprehensively summarize the existing evidence that points to the potential role of dysbiosis in the malignant transformation of extraintestinal organs such as the liver, breast, lung, and pancreas. …”
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932
Effects of Stroke-ⅡOral Liquid on TLR4/MyD88/NF-κB Signal Pathway in Chemical Damaged PC12 Cells
Published 2016-12-01“…All cells were divided into blank control group, model group, low dose group and high dose group. The cell proliferation was observed by MTT assay, the expression of TLR4, MyD88 and NF-κB mRNA were detected by RT-PCR, and their protein expressions were detected by Western Blot.Results:Compared with the blank control group, the proliferation of PC12 cells in the model group was decreased (<italic>P</italic><0.01), and the expression of TLR4, MyD88 and NF-κB mRNA and protein were increased significantly (<italic>P</italic><0.01, <italic>P</italic><0.05). …”
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933
Antitumor Activity of Whole-Plant Extracts from In Vitro Cultured and Wild-Growing <i>Clinopodium vulgare</i> Plants on a Panel of Human Tumor Cell Lines
Published 2025-01-01“…The cell viability and migration assays demonstrate the selective anticancer effect of the extract and significant inhibition of cancer cell proliferation and motility. The fluorescence microscopy and cell cycle analyses indicate that the antitumor activity of the in vitro plant extract was related to both antiproliferative and proapoptotic effects. …”
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934
Prosaposin – A plausible biomarker in head and neck squamous cell carcinoma
Published 2024-03-01“…A significant decrease in PSAP levels was found post-treatment. Cell proliferation, cell migration, cell invasion, and colony formation were found to be significantly reduced with the downregulation of PSAP. …”
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935
Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2
Published 2022-01-01“…Importantly, OSCC-CSC-sEV transfer of UCA1, by targeting LAMC2, promoted M2 macrophage polarization and inhibited CD4+ T-cell proliferation and IFN-γ production in vitro and in vivo. …”
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936
Review on the Injury and Repair Mechanism of Skeletal Muscle Contusions
Published 2022-02-01“…We reviewed the injury and repair mechanism of skeletal muscle contusions (SMC), it is explained in five aspects, such as the theories of myosatellite cell proliferation and differentiation, Ca<sup>2+</sup> mediated membrane repair, endoplasmic reticulum stress (ERS) and autophagy. …”
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937
The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class?
Published 2015-01-01“…Recent studies have been focusing on the putative ability of DPP-4 inhibitors to preserve pancreas function, in particular due to the inhibition of apoptotic pathways and stimulation of β cell proliferation. In addition, other cytoprotective effects on other organs/tissues that are involved in serious T2DM complications, including the heart, kidney, and retina, have been increasingly reported. …”
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938
Transcription factor DREF regulates expression of the microRNA gene <i>bantam in Drosophila melanogaster</i>
Published 2024-04-01“…At the cellular level, bantam stimulates cell proliferation and prevents apoptosis. The bantam gene is a target of several conserved signaling cascades, in particular, Hippo. …”
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939
Peroxisome Proliferator-Activated Receptor γ Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy
Published 2023-01-01“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a key nuclear receptor transcription factor that is highly expressed in trophoblastic cells during embryonic attachment and is accompanied by rapid cell proliferation and increased lipid accumulation. We previously showed that the autophagy pathway is activated in cells after activation of PPARγ, accompanied by increased lipid accumulation. …”
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940
B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies
Published 2011-01-01“…B7-H4, a newly identified B7 homolog, plays a key role in maintaining T-cell homeostasis by reducing T-cell proliferation and cytokine production. The relationship between B7-H4 and allograft survival/autoimmunity has been investigated recently in both islet transplantation and the nonobese diabetic (NOD) mouse models. …”
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