-
341
Exosomes in Oral Diseases: Mechanisms and Therapeutic Applications
Published 2025-01-01“…In OSCC tumor-derived exosomes promote cancer progression through cell proliferation, migration, invasion, and angiogenesis, and serve as potential biomarkers for early diagnosis and prognosis. …”
Get full text
Article -
342
Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer...
Published 2025-01-01“…The functions of APOE in PTC cell proliferation and invasion were confirmed through in vivo and in vitro assays. …”
Get full text
Article -
343
Overview of preclinical and phase II clinical studies on Pegmolesatide’s long-term erythropoiesis stimulating effect via EPOR-mediated signal transduction
Published 2025-02-01“…Pegmolesatide promoted UT-7 cell proliferation & survival and suppressed apoptosis. …”
Get full text
Article -
344
Systemic and mammary inflammation and mammary gland development of Holstein dairy cows around dry-off and calving
Published 2025-02-01“…Mammary alveolar, stromal, and total cell proliferation rates peaked on d 7 after dry-off in mammary tissue collected from LTD cows and were greater in the late dry period than early lactation. …”
Get full text
Article -
345
The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma
Published 2013-01-01“…We also demonstrated that EGF led to the activation of the EGFR/PI3K/Akt/cyclinD1 signaling pathway, which played a critical role in EGF-induced cell proliferation and cell cycle progression of EACKs. …”
Get full text
Article -
346
Perioperative Management of Patient with Systemic Mastocytosis Going for Total Thyroidectomy
Published 2025-01-01“… Systemic mastocytosis (SM) is a rare disorder affecting 1 in 10,000 individuals, characterised by abnormal mast cell proliferation in extra-cutaneous organs, resulting in a variety of presentations ranging from mild asymptomatic disease to life-threatening tissue-destructive disease. …”
Get full text
Article -
347
DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis
Published 2006-01-01“…DYRKs (dual-specificity tyrosine-regulated kinases) are an emerging family of evolutionarily conserved dual-specificity kinases that play key roles in cell proliferation, survival, and development. The research in the last years suggests a relevant conserved function during neuronal development, related to proliferation and/or differentiation for DYRK1A. …”
Get full text
Article -
348
A Role for the Cytoskeleton in Heart Looping
Published 2007-01-01“…It is becoming clear from our experiments and those of others that left-right differences in cell proliferation in the second heart field (anterior heart field) drives the dextral direction. …”
Get full text
Article -
349
The role of laminins in cancer pathobiology: a comprehensive review
Published 2025-01-01“…In this article, we review the diverse functions of LMs in promoting cancer cell proliferation, adhesion, and migration—critical steps in cancer metastasis. …”
Get full text
Article -
350
A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
Published 2008-01-01“…Recent evidence suggests that stromal PPARβ/δ regulates tumor endothelial cell proliferation and promotes differentiation leading to the properly orchestrated events required for tumor blood vessel formation. …”
Get full text
Article -
351
Platelet Rich Plasma for Treatment of Rheumatoid Arthritis: Case Series and Review of Literature
Published 2020-01-01“…PRP may help to decrease joint inflammation by modulating synovial cell proliferation and differentiation and inhibition of catabolic pathways in various articular conditions. …”
Get full text
Article -
352
Cytotoxicity and Antiangiogenic Activity of Turbinaria ornata Agardh and Padina australis Hauck Ethanolic Extracts
Published 2018-01-01“…Brown macroalgae species are constantly reported as potential sources of bioactive compounds useful in inhibiting cell proliferation and vascular formation. Thus, this study was conducted to determine and compare the in vitro cytotoxic activities of Turbinaria ornata Agardh and Padina australis Hauck ethanolic extracts against baker’s yeast (Saccharomyces cerevisiae) using the resazurin reduction test (RRT) and investigate their in vivo antiangiogenic activity through duck (Anas platyrhynchos) chorioallantoic membrane (CAM) assay. …”
Get full text
Article -
353
Endogenous Proliferation after Spinal Cord Injury in Animal Models
Published 2012-01-01“…All SCI animal models experience a similar peak of cell proliferation three days after injury; however, each specific type of injury promotes a specific and distinct stem cell response. …”
Get full text
Article -
354
The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents
Published 2013-01-01“…The four most predominant mechanisms for metal carcinogenicity include (1) interference with cellular redox regulation and induction of oxidative stress, (2) inhibition of major DNA repair, (3) deregulation of cell proliferation, and (4) epigenetic inactivation of genes by DNA hypermethylation. …”
Get full text
Article -
355
Perioperative Management of Patient with Systemic Mastocytosis Going for Total Thyroidectomy
Published 2025-01-01“… Systemic mastocytosis (SM) is a rare disorder affecting 1 in 10,000 individuals, characterised by abnormal mast cell proliferation in extra-cutaneous organs, resulting in a variety of presentations ranging from mild asymptomatic disease to life-threatening tissue-destructive disease. …”
Get full text
Article -
356
Wnt5a Signaling in Normal and Cancer Stem Cells
Published 2017-01-01“…Recent studies show the involvement of Wnt5a signaling in regulating normal and cancer stem cell self-renewal, cancer cell proliferation, migration, and invasion. In this article, we review recent findings regarding the molecular mechanisms and roles of Wnt5a signaling in stem cells in embryogenesis and in the normal or neoplastic breast or ovary, highlighting that Wnt5a may have different effects on target cells depending on the surface receptors expressed by the target cell.…”
Get full text
Article -
357
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials
Published 2018-01-01“…The WHO grade IV glioblastoma (GBM), characterized by rapid cell proliferation, easily recrudescent, high morbidity, and mortality, is the most common, devastating, and lethal gliomas. …”
Get full text
Article -
358
Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney
Published 2023-01-01“…Moreover, we identified that in lupus kidney, neutrophils could provide IL-6 to facilitate ferroptosis resistance in B cells via SLC7A11, and inhibition of SLC7A11 could significantly enhance ferroptosis in B cells and could decrease B cell proliferation. This study helps understand the crosstalk between neutrophils and B cells in the kidney in the development of lupus.…”
Get full text
Article -
359
Cytokine Secretion of Peripheral Blood Mononuclear Cells by Hydnocarpus anthelminthicus Seeds
Published 2018-01-01“…Cell viability was detected with WST-1 cell proliferation assay reagent. Proinflammatory cytokines were quantified using ELISA with a specific antibody. …”
Get full text
Article -
360
The role of complement in tumor immune tolerance and drug resistance: a double-edged sword
Published 2025-01-01“…On the one hand, the complement system has the capacity to directly inhibit cancer cell proliferation via specific pathways, thereby exerting a beneficial anti-tumor effect. …”
Get full text
Article