Yinzhihuang injection induces apoptosis and suppresses tumor growth in acute myeloid leukemia cells. by Zhe Huang, Yunfu Shen, Xianming Fan, Qulian Guo, Wenzhe Ma

“…The active AMPK negatively regulated the downstream target mTORC1, leading to the inhibition of cell proliferation and induction of apoptosis. Pretreatment with the AMPK inhibitor compound C rescued YZHI induced apoptosis and partially restored cell proliferation of HL-60. …”
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PRMT6 promotes colorectal cancer progress via activating MYC signaling by Xin Zhang, Mingxin Jin, Yali Chu, Fengjun Liu, Hui Qu, Cheng Chen

“…This post-translational modification is crucial for PRMT6-induced cancer cell proliferation. Xenograft models further validated that PRMT6 knockdown results in reduced tumor growth and decreased c-MYC levels. …”
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Targeting compensatory proliferation signals in oral cancer by Loganathan Kavitha, Vijayashree Priyadharsini J, Anitha P, Paramasivam A

“…These microvesicles provide proliferative signals and act as mutagens, triggering cell proliferation, angiogenesis, immune evasion, metastasis, and invasion. …”
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Expression of interleukin-17 in oral tongue squamous cell carcinoma and its effect on biological behavior by Lina Jiang, Zhenghao Ma, Luwen Song, Chenchen Zhu, Jiancheng Li, Zhenxing Su, Hongsheng Liu

“…With increasing IL-17 concentration, cell proliferation, migration, and invasion increased, and the apoptosis rate decreased. …”
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Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell Lung Cancer Cells by Inhibiting MCL-1 Expression via MET/STAT3/Akt Pathway by Lile Wang, Lu Xu, Shuhua Han, Xiaoli Zhu

“…Cell viability was assessed by the cell counting kit 8 assay. Cell proliferation, migration, and invasion were determined using the colony formation assay and transwell assay. …”
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Construction of a Multicellular Communication Network Model for Cell Co-Culture Technology and Evaluation of Its Simulation Capability by Yuan-Yuan Geng, Chao Wei, Guo-Fei Chen, Bai-Xia Zhang

“…Objective: Cell co-culture technology has been widely used to analyze the effects of drugs on cell proliferation and the expression of some proteins in cells, especially in the field of traditional Chinese medicine (TCM); however, the interactions between cells and the transmission of TCM effects between cells have not been adequately studied. …”
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Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma by Tatsuya Morinishi, Yasunori Tokuhara, Hiroyuki Ohsaki, Emi Ibuki, Kyuichi Kadota, Eiichiro Hirakawa

“…Peroxisome proliferator-activated receptor alpha (PPAR-α) belongs to the PPAR family and plays a critical role in inhibiting cell proliferation and tumorigenesis in various tumors. …”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma. by Haofei Wang, Zhen Liu, Zesheng Peng, Peng Lv, Peng Fu, Xiaobing Jiang

“…Knockdown of TSPAN13 inhibited GBM cell proliferation, migration, and invasion, and enhanced sensitivity to TMZ treatment. …”
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Clinical Significance of NKD Inhibitor of WNT Signaling Pathway 1 (NKD1) in Glioblastoma by Lijun Li, Ruiying Gao, Weizhong Huangfu, Fang Zhang, Ruixia Wang

“…Overexpressing NKD1 in glioblastoma cell lines can significantly attenuate cell proliferation. In addition, expression of NKD1 in glioblastoma is negatively correlated to the T cell infiltration, indicating it may have crosstalk with the tumor immune microenvironment. …”
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Phenotypic alterations in articulating joint cells: Role of mechanically loaded MSC secretome by Yann D. Ladner, Ursula Menzel, Keith Thompson, Angela R. Armiento, Martin J. Stoddart

“…Inhibition of T cell proliferation was also observed. This in vitro model could enhance our understanding how mechanical load induces changes in MSC secretome benefitting cartilage healing.…”
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Radiation-Induced Growth Retardation and Microstructural and Metabolite Abnormalities in the Hippocampus by Shaefali P. Rodgers, Janice A. Zawaski, Iman Sahnoune, J. Leigh Leasure, M. Waleed Gaber

“…CRT suppressed cell proliferation in the hippocampal subgranular zone acutely. …”
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ErbB4 as a Potential Molecular Target in the Treatment of Esophageal Squamous Cell Cancers by Ke Zhao, Bao-Jun Chen, Zhi-Guo Chen

“…Furthermore, miRNA-140-5p transfected cell significantly controlled the cell proliferation and enhanced the apoptosis of multiple cells. …”
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Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage by Francesca Diomede, Thangavelu Soundara Rajan, Valentina Gatta, Marco D’Aurora, Ilaria Merciaro, Marco Marchisio, Aurelio Muttini, Sergio Caputi, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

“…Methods. Cell proliferation assay, beta galactosidase staining, immunocytochemistry, and real-time PCR techniques were applied. …”
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Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer by Lingjuan Zeng, Chunyan Chen, Chanjiao Yao

“…Meanwhile, the downregulation of KDM1A or overexpression of DACT1 could suppress the cell proliferation and migration ability in HeLa and SiHa cells. …”
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FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling by Haiyan Tai, Zhiyong Wu, Su’an Sun, Zhigang Zhang, Congjian Xu

“…Loss of function of FGFRL1 significantly influenced cell proliferation, apoptosis, and migration of OC cells in vitro and tumor growth in vivo. …”
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Investigating the Prognostic and Oncogenic Roles of Membrane-Associated Ring-CH-Type Finger 9 in Colorectal Cancer by Jiayan Zhang, Qinghan Jiao, Zhigang Chen

“…In vitro experiments involved siRNA-mediated MARCHF9 knockdown in COAD cell lines (SW480 and LoVo). Cell proliferation and invasion assays were conducted to investigate MARCHF9’s functional relevance. …”
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Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma by RUAN Zhao-wei, JIAO Xue-feng, XIAO Gao-tian, CHEN Jin-ling, LI Jun, LV Shu-ying

“…TMED2 knockdown reduced cell proliferation, increased the apoptosis rate in SCC-4 cells, and led to a higher proportion of cells in the G0/G1 phase and a lower proportion in the S phase. …”
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KYNU as a Biomarker of Tumor-Associated Macrophages and Correlates with Immunosuppressive Microenvironment and Poor Prognosis in Gastric Cancer by Kaiyu Shen, Binyu Chen, Liu Yang, Wencang Gao

“…KYNU was overexpressed in GC cells in vitro, and KYNU knockout significantly inhibited GC cell proliferation and invasion. Conclusion. High KYNU expression promotes an adverse immune microenvironment and low survival rates in GC. …”
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CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance by Dijie Zheng, Yazhu Deng, Lu Deng, Zhiwei He, Xinghao Sun, Yanyu Gong, Binbin Shi, Deqin Lu, Chao Yu

“…Additionally, the biological functions of CDCA7 were assessed using cell proliferation, wound healing, and Transwell assays. …”
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mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase by Brittany Q. Pham, Sang Ah Yi, Alban Ordureau, Heeseon An

“…Summary: One critical aspect of cell proliferation is increased nucleotide synthesis, including pyrimidines. …”
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