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101
Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer
Published 2025-01-01“…Conclusions Our findings unveil DAPK1-215 as a molecular brake on DAPK1 expression, influencing cancer cell migration and invasion in a context-dependent manner. …”
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102
The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer
Published 2016-01-01“…In addition, interaction of HA and CD44 promotes EGFR-mediated pathways, consequently leading to tumor cell growth, tumor cell migration, and chemotherapy resistance in solid cancers. …”
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103
Regulators of Actin Dynamics in Gastrointestinal Tract Tumors
Published 2015-01-01“…Reorganization of the actin cytoskeleton underlies cell migration in a wide variety of physiological and pathological processes, such as embryonic development, wound healing, and tumor cell invasion. …”
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104
Detection of the Hematopoietic Stem and Progenitor Cell Marker CD133 during Angiogenesis in Three-Dimensional Collagen Gel Culture
Published 2013-01-01“…Lovastatin strongly inhibited cell migration from aortic explants and caused the degradation of the capillary tubes. …”
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105
Cardiovascular Effects Mediated by HMMR and CD44
Published 2021-01-01“…Both RHAMM and CD44 are involved in cell migration and wound healing. However, their close association with CVD is not fully understood. …”
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106
Sugar Antennae for Guidance Signals: Syndecans and Glypicans Integrate Directional Cues for Navigating Neurons
Published 2006-01-01“…Recently, heparan sulfate proteoglycans (HSPGs), which are present on the cell surface of neurons and in the extracellular matrix through which neurons and axons migrate, have been found to play a role in regulating cell migration and axon guidance. Intriguingly, the large number of distinct modifications that can be put onto the sugar side chains of these PGs would in principle allow for an enormous diversity of HSPGs, which could help in regulating the vast number of guidance choices taken by individual neurons. …”
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107
The Oxidative State of Chylomicron Remnants Influences Their Modulation of Human Monocyte Activation
Published 2012-01-01“…Chylomicron remnants (CMRs) contribute directly to human monocyte activation in vitro, by increasing reactive oxygen species (ROS) production and cell migration. In this study, the effects of the oxidative state of CMR on the degree of monocyte activation was investigated. …”
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108
Mesenchymal Stem Cells and their Derived Exosomes Promote Malignant Phenotype of Polyploid Non-Small-Cell Lung Cancer Cells through AMPK Signaling Pathway
Published 2022-01-01“…Compared with the control group, MSCs and MSC-exosomes significantly promoted epithelial mesenchymal transformation, cell migration, antiapoptosis, and autophagy in the polyploid A549 and H1299 by activating AMPK signaling pathway, but no significant changes were observed in MSC-CM treatment. …”
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109
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo
Published 2025-01-01“…Data furthermore indicate that the exosomes released through this NRP1-driven mechanism effectively transfer miR-210-3p to human endothelial cells, causing paracrine downregulation of the regulatory cue ephrin-A3 and promotion of cell migration. The mechanistic involvement of miR-210-3p in this pathway was confirmed by applying a specific antago-miR. …”
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110
Spatial stochastic models of cancer: Fitness, migration, invasion
Published 2013-03-01“…Thus, a decrease in the reproductive potentialcan be compensated by an increase in cell migration. We furtherdemonstrate that the neutral ridges (the set of all types with theinvasion probability equal to that of the host cells) remain invariantunder the increase of system size (for large system sizes), thusmaking the invasion probability a universal characteristic of thecells' selection status. …”
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111
MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells
Published 2023-01-01“…The results demonstrated that the siRNA significantly reduced the MLLT11 mRNA levels. Moreover, cell migration and invasion, as well as the protein levels of phosphatidylinositol 3-kinase (PI3K), AKT, matrix metalloproteinase (MMP) 2, and MMP9, were significantly lower in the groups treated with siRNA while the apoptosis was augmented. …”
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112
Migration and proliferation drive the emergence of patterns in co-cultures of differentiating vascular progenitor cells
Published 2024-08-01“…Our results suggested that post-differentiation cell migration and proliferation when balanced could generate between 30–70% of each cell type enabling the formation of vascular patterns. …”
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113
Hydromethanolic extracts of Morus alba L. (Mulberry) young and ripe fruit induces apoptosis in lung carcinoma cells (A549)
Published 2025-01-01“…Moreover, the extracts effectively inhibited cell migration. Treatment of extracts elevated reactive oxygen species (ROS) production which resulted in disruption of mitochondrial membrane potential, and induced the process of apoptosis in lung carcinoma cells. …”
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114
LOX-1, OxLDL, and Atherosclerosis
Published 2013-01-01“…Oxidized low-density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation and progression by several mechanisms, including the induction of endothelial cell activation and dysfunction, macrophage foam cell formation, and smooth muscle cell migration and proliferation. Vascular wall cells express on their surface several scavenger receptors that mediate the cellular effects of OxLDL. …”
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115
c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes
Published 2012-01-01“…In primary cultures of human renal epithelial cells, CsA activates JNK signaling, and the treatment with a JNK inhibitor reduces the occurrence of cell shape changes, E-cadherin downregulation, cell migration, and Snail-1 expression. Our results suggest that CsA activates JNK signaling, which, in turn, may participate in the morphological alterations through the regulation of Snail-1 expression.…”
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116
Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer
Published 2025-01-01“…In addition to the various roles TEM8 plays in oncogenesis, including angiogenesis, epithelial-to-mesenchymal transition, and cell migration, it has also been shown that the overexpression of the ANTXR1 gene in solid tumors correlates with poor prognostic indicators in several solid tumor histologies. …”
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117
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways
Published 2019-09-01“…The obtained data showed that TAD1822-7 decreased Bel-7402 cell viability and colony formation ability and suppressed cell migration. TAD1822-7 effectively inhibited blood vessel formation in an aortic ring assay to examine angiogenesis. …”
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118
Wound Healing and Omega-6 Fatty Acids: From Inflammation to Repair
Published 2018-01-01“…Among the fatty acids, much attention has been given to omega-6 (ω-6) fatty acids since they can modulate cell migration and proliferation, phagocytic capacity, and production of inflammatory mediators. …”
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119
Omentin-1 Ameliorated Free Fatty Acid-Induced Impairment in Proliferation, Migration, and Inflammatory States of HUVECs
Published 2020-01-01“…Scratch and transwell assays were used to evaluate cell migration. Factors secreted by endothelial cells after injury were detected by western blotting, reverse-transcription quantitative polymerase chain reaction, and cellular fluorescence assay. …”
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120
MIMO-Based Forward-Looking SAR Imaging Algorithm and Simulation
Published 2014-01-01“…This imaging method can implement range compression, secondary range compression (SRC), and range cell migration correction (RCMC) effectively. Finally, some simulations of point targets and comparison results confirm the efficiency of our proposed algorithm.…”
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