Showing 221 - 240 results of 287 for search '"cell migration"', query time: 0.10s Refine Results
  1. 221

    The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility by E. Di Zazzo, A. Feola, C. Zuchegna, A. Romano, C. F. Donini, S. Bartollino, C. Costagliola, R. Frunzio, P. Laccetti, M. Di Domenico, A. Porcellini

    Published 2014-01-01
    “…Furthermore, the p85αPI3KS83 phosphorylation plays a central role in the control of insulin-mediated cell proliferation, cell migration, and adhesion. This study highlights the p85αPI3KS83 role as a key regulator of cell proliferation and motility induced by insulin in MCF-7 cells breast cancer model.…”
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  2. 222

    Filamented hydrogels as tunable conduits for guiding neurite outgrowth by Hao Liu, Anna Puiggalí-Jou, Parth Chansoria, Jakub Janiak, Marcy Zenobi-Wong

    Published 2025-04-01
    “…While significant differences in neurite outgrowth and alignment were observed between bulk and FLight gels, further increases in porosity from 40 % to 70 % enhanced cell migration and axon bundling without significantly affecting maximal outgrowth. …”
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  3. 223

    Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration by Jouda Gamara, Lynn Davis, Emmanuelle Rollet-Labelle, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Fawzi Aoudjit, Sylvain G. Bourgoin

    Published 2020-01-01
    “…In PMN-Arf6 cKO mice, the recruitment of PMNs into the dorsal air pouch injected with LPS or the chemoattractant fMLP was significantly diminished. Impaired cell migration correlated with reduced cell surface expression of CD11a and CD11b in Arf6 cKO PMNs. …”
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  4. 224
  5. 225

    Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

    Published 2025-02-01
    “…Findings of in vitro studies revealed considerable inhibitory effects of sunitinib and analogs on LoVo cell migration and invasion in hypoxic condition. Gelatin zymography and qPCR analysis indicated decreased activity of MMP-2 and MMP-9, along with downregulation of EMT transcription factors in hypoxic condition. …”
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  6. 226

    GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

    Published 2025-02-01
    “…The effects of AST on cell migration and angiogenesis were studied using wound healing assays and angiogenesis assays. …”
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    Article
  7. 227

    Colony Formation, Migratory, and Differentiation Characteristics of Multipotential Stromal Cells (MSCs) from “Clinically Accessible” Human Periosteum Compared to Donor-Matched Bone... by Heather E. Owston, Payal Ganguly, Giuseppe Tronci, Stephen J. Russell, Peter V. Giannoudis, Elena A. Jones

    Published 2019-01-01
    “…This study is aimed at comparing human periosteum and donor-matched iliac crest BM MSC content and characterising MSCs in terms of colony formation, growth kinetics, phenotype, cell migration patterns, and trilineage differentiation capacity. …”
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  8. 228

    TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

    Published 2025-02-01
    “…Knockdown of TWIST1 or HK2 enhanced the inhibitory effects of 2DG on cell migration and invasion. Treatment with Elesclomol-Cu and 2DG significantly reduced the expression of the cuproptosis-related factor FDX1 with no impact on other cell death factors. …”
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  9. 229
  10. 230

    Unlocking melanoma Suppression: Insights from Plasma-Induced potent miRNAs through PI3K-AKT-ZEB1 axis by Pradeep Bhartiya, Apurva Jaiswal, Manorma Negi, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik

    Published 2025-02-01
    “…Various biological processes and underlying molecular mechanisms were assessed using Alamar Blue, propidium iodide (PI) uptake, cell migration, and clonogenic assays followed by qRT-PCR and flow cytometry. …”
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    Article
  11. 231

    Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail by Rongbing Shu, Zhuanyi Yu, Jianmin Wu, Qiuxin Cheng, Zhihao Peng, Huaqiang Zhou, Min Zhao

    Published 2025-01-01
    “…Transwell invasion and scratch assays were used to assess cell migration and invasion. WB was employed to detect the expression of Id-1, Snail, and epithelial-mesenchymal transition (EMT)-related proteins (E-cadherin, vimentin, and N-cadherin) in the OS cells of each group. …”
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  12. 232

    Effect of Interferon-γ on the Basal and the TNFα-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation by Mario Rotondi, Francesca Coperchini, Oriana Awwad, Patrizia Pignatti, Christian A. Di Buduo, Vittorio Abbonante, Flavia Magri, Alessandra Balduini, Luca Chiovato

    Published 2016-01-01
    “…Transwell migration assay showed that (i) CXCL8 increased cell migration in both TPC-1 and BCPAP cells; (ii) IFNγ significantly reduced the migration only of BCPAP cells; and (iii) CXCL8 reverted the effect of IFNγ. …”
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  13. 233

    Aberrant Expression of JAM2 Inhibits Invasion and Migration in Lung Adenocarcinoma by Jun Chen, Yuan Cui, Zhimeng Chen, Hao Ding, Chang Li, Sheng Ju, Cheng Ding, Chun Xu, Jun Zhao, Xin Tong

    Published 2025-01-01
    “…Its downregulation in LUAD, potential role as a prognostic gene, and influence on cell migration, invasion, and inflammatory infiltration make it a valuable target for further research and development of therapeutic strategies.…”
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  14. 234
  15. 235

    Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling by Lingli Long, Yubin Li, Shuang Yu, Xiang Li, Yue Hu, Tengfei Long, Liqin Wang, Wenwen Li, Xiaoxin Ye, Zunfu Ke, Haipeng Xiao

    Published 2019-01-01
    “…HRECs were cultured in high glucose- (30 mM D-glucose) and hypoxia (cobalt chloride-treated)-stimulated diabetic condition to evaluate the antiangiogenic effects of SCU by CCK-8 test, cell migration experiment (wound healing and transwell), and tube formation experiment. …”
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  16. 236

    Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis by Flora Magno de Jesus Oliveira, Cassiano Felippe Gonçalves-de-Albuquerque, Isabel Matos Medeiros de Moraes, Patrícia Alves Reis, Vinicius Novaes Rocha, Patrícia Torres Bozza, Adriana Ribeiro Silva, Hugo Caire de Castro Faria Neto

    Published 2020-01-01
    “…We measured plasma biochemical markers of organ dysfunction, cell migration, cell activation, bacterial elimination, production of nitric oxide 24 h after CLP, survival rate for 7 days, and cognitive impairment 15 days after CLP. …”
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  17. 237

    Nicotine-induced CHRNA5 activation modulates CES1 expression, impacting head and neck squamous cell carcinoma recurrence and metastasis via MEK/ERK pathway by Chen Feng, Wei Mao, Chenyang Yuan, Pin Dong, Yuying Liu

    Published 2024-10-01
    “…Knockdown of CHRNA5 can reduce cell migration, invasion, and proliferation, whereas nicotine exposure can reverse this trend. …”
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  18. 238

    Establishing a Surgical Procedure for Rhesus Epiretinal Scaffold Implantation with HiPSC-Derived Retinal Progenitors by Ziming Luo, Kang Li, Kaijing Li, Bikun Xian, Ying Liu, Sijing Yang, Chaochao Xu, Zhigang Fan, Shoutao Lu, Haijun Zhang, Jian Ge

    Published 2018-01-01
    “…The successful delivery and long-term fixation provide a prerequisite for cell migration and integration.…”
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  19. 239

    Composition analysis and mechanism of Guizhi Fuling capsule in anti-cisplatin-resistant ovarian cancer by Lei Dou, Yan Yan, Enting Lu, Fangmei Li, Dongli Tian, Lei Deng, Xue Zhang, Rongjin Zhang, Yin Li, Yi Zhang, Ye Sun

    Published 2025-02-01
    “…Then, LC-MS/MS analysis of GFC chemical composition. qRT-PCR, scratch tests, transwell, pseudopodium formation, immunofluorescence, and western blotting were used to explore the mechanism by which GFC inhibited A2780/DDP cell migration and invasion. Finally, the anti-tumor efficacy of GFC was verified by in vivo experiments. …”
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  20. 240

    Investigation of <i>ITGB3</i> Heterogeneity to Overcome Trastuzumab Resistance in HER2-Positive Breast Cancer by Asiye Busra Boz Er

    Published 2024-12-01
    “…The impact of <i>ITGB3</i> on TGF-β-responsive genes <i>(WWP1</i>, <i>CARM1</i>, <i>RASGRP1</i>, <i>THBS1</i>, <i>KCTD5</i>, <i>SGCA</i>, <i>EIF3S6</i>, <i>MCAM</i>, <i>FXR2</i>, <i>MTMR3</i>, <i>SOCS3</i>, <i>SLC2A4RG</i>, <i>MMP2</i>, <i>MMP9</i>, and <i>HSP47)</i> and cell migration (<i>Col4a1</i>, <i>fibronectin</i>, <i>ICAM1</i>, <i>Timp2</i>, and <i>vimentin</i>) was analysed using luciferase reporter assays and real-time PCR. …”
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