Unraveling the Molecular Nexus between GPCRs, ERS, and EMT by Niti Kumari, Somrudee Reabroi, Brian J. North

“…Many GPCRs modulate ERS and UPR signaling via ERS sensors, IRE1α, PERK, and ATF6, to support cancer cell survival and inhibit cell death. By regulating downstream signaling pathways such as NF-κB, MAPK/ERK, PI3K/AKT, TGF-β, and Wnt/β-catenin, GPCRs also upregulate mesenchymal transcription factors including Snail, ZEB, and Twist superfamilies which regulate cell polarity, cytoskeleton remodeling, migration, and invasion. …”
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Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages. by Girish Ramachandran, Darren J Perkins, Patrick J Schmidlein, Mohan E Tulapurkar, Sharon M Tennant

“…This difference in proinflammatory cytokine production and cell death between S. Typhimurium ST19 and ST313 strains could be explained, in part, by an increased production of flagellin by ST19 strains. …”
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The role of TASK-1 and TRPV1 channels in the male reproductive system by Dawon Kang, Eun-A Ko

“…This channel is thought to contribute programmed cell death within the testes, particularly impacting Leydig cell survival. …”
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Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment. by Yajia Chen, Jingxian Zhang, Weiqian Zheng, Hongwu Xu

“…In recent studies, regulatory cell death (RCD) has been identified as an effective mechanism to suppress glioma. …”
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A Novel In Situ Dendritic Cell Vaccine Triggered by Rose Bengal Enhances Adaptive Antitumour Immunity by Lanlin Zhang, Jiangyuan Du, Qian Song, Chufan Zhang, Xianghua Wu

“…Recent studies have shown that Rose Bengal (RB) can effectively induce immunogenic cell death (ICD) in cancer cells, presenting whole tumour antigens for DC processing and presentation. …”
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Epigenetic regulation and post-translational modifications of ferroptosis-related factors in cardiovascular diseases by Chunlu Jing, Yupeng Wu, Yuzhu Zhang, Zaihan Zhu, Yong Zhang, Zhen Liu, Dandan Sun

“…In the past decade, ferroptosis (a form of iron-dependent regulated cell death) has been reported to contribute to the pathogenesis and progression of various diseases. …”
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Comprehensive analysis of cuproptosis-related genes in immune infiltration and development of a novel diagnostic model for acute kidney injury by Yajing Li, Yingxue Ding

“…Cuproptosis, a recently identified form of programmed cell death dependent on copper, is closely linked to mitochondrial respiration and contributes to various diseases. …”
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E3 ubiquitination ligase XIAP lightens diabetes‐induced cognitive impairment by inactivating TXNIP‐ERS‐mediated neuronal injury by Qin Zhang, Hai‐Jin Huang, Jing‐Ling Zhang, Ying Tian, Ying Hu

“…This study aims to elucidate the role and mechanisms of the X‐linked inhibitor of apoptosis protein (XIAP)/thioredoxin‐interacting protein (TXNIP) in hippocampal neuron cell death and cognitive function within DCD models. …”
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Evaluation of antifungal effect of amphotericin B in comparison with nystatin on Candida species derived from patients undergoing head-and-neck radiotherapy

“…Amphotericin B is a polyene antifungal drug that combines with ergosterol to cause cell death and is more effective on fungal species than routine antifungals such as nystatin. …”
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N-Acetylcysteine in Combination with IGF-1 Enhances Neuroprotection against Proteasome Dysfunction-Induced Neurotoxicity in SH-SY5Y Cells by Benxu Cheng, Pinki Anand, Anxiu Kuang, Feroz Akhtar, Virginia L. Scofield

“…In addition, MG132 treatment leads to endoplasmic reticulum (ER) stress and autophagy-mediated cell death. All of these events can be attenuated without obvious reduction of MG132 induced protein ubiquitination by first treating the cells with NAC and IGF-1 separately or simultaneously prior to exposure to MG132. …”
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Bioinformatics analysis of miR-2861 and miR-5011-5p that function as potential tumor suppressors in colorectal carcinogenesis by Alper Aytekin, Hikmet Kadakal, Deniz Mihcioglu, Turkan Gurer

“…The GO and KEGG pathway analysis showed that miR-2861 and miR-5011-5p may participate in multiple the biological process, cellular components, and molecular function subcategories such as mitotic cell cycle, regulation of small GTPase mediated signal transduction, cell death, and acid binding transcription factor activity. …”
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Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change by Muhammad Abubakkar Azmat, Malaika Zaheer, Muhammad Shaban, Saman Arshad, Muhammad Hasan, Alyan Ashraf, Muhammad Naeem, Aftab Ahmad, Nayla Munawar

“…., pathogen infection, nutrient deficiency, plant senescence, heat stress, drought, osmotic stress, and hypoxia induce autophagy in plants. Cell death is not a stress, which induces autophagy but in contrast, sometimes it is a consequence of autophagy. …”
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Role of calpain system in meat tenderness: A review by Z.F. Bhat, James D. Morton, Susan L. Mason, Alaa El-Din A. Bekhit

“…These ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death phenomena. This review discusses the role and contribution of the calpain system and the factors that influence calpain activity during aging. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…The cytomorphological changes associated with the chloroform extract and AO/EB dual staining indicated apoptotic cell death. An analysis of ADME properties of compounds obtained in GC-MS analysis of the chloroform extract showed that compounds such as Cyclododecanol, Sulfurous acid hexyl octyl ester, 2,4-Ditert-Butylphenol and 1,2-benzenedicarboxylic acid had favourable physicochemical and drug-likeness characteristics. …”
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Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease by Ylva Tranæus Lindblad, Ľubomíra Tóthová, Peter Celec, Karolina Kublickiene, Peter Bárány, Milan Chromek

“…Extracellular or cell-free DNA (exDNA) originates from virtually all tissues, being released during cell death, and stimulates the innate immune system. …”
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Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon by Prathiksha Srikanthan, Suresh Malakondaiah, Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

“…This editorial aims to review the current genetic and molecular data of OSCC treatment with an emphasis on the Programmed cell death protein 1 (PD-1)/ligand PD-L1 pathway and novel biomarkers. …”
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Polystyrene Nanoplastics Elicit Multiple Responses in Immune Cells of the <i>Eisenia fetida</i> (<i>Savigny</i>, 1826) by Huijian Shi, Yaoyue Wang, Xiangxiang Li, Xiaoyang Wang, Yuntao Qi, Shaoyang Hu, Rutao Liu

“…The difficulty of the NP in causing cell death by disrupting the plasma membrane was demonstrated by the results of the lactate dehydrogenase release assays in relation to cell necrosis. …”
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Herbicide Widespread: The Effects of Pethoxamid on Nonalcoholic Fatty Liver Steatosis In Vitro by Anna Virginia Adriana Pirozzi, Antonietta Stellavato, Chiara Schiraldi, Mariateresa Giuliano

“…Based on our data, we can argue that NAFLD hepatic cells react to pethoxamid trying detoxifying strategies, ready to undergo cell death to avoid further degeneration. Downregulation of cytochrome can lead to the hypothesis that pethoxamid should not induce herbicide resistance.…”
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Dioscin from Polygonatum sibiricum induces apoptosis and autophagy in Ishikawa human endometrial cancer cell and in vivo by Xiaoli Li, Runhui Ma, Zhijing Ni, Wei Wang, Kiran Thakur, Jianguo Zhang, Zhaojun Wei

“…The high-throughput sequencing data indicated that dioscin not only promoted apoptosis, including decrease of poly ADP-ribose polymerase (PARP) and B-cell lymphoma-2 (Bcl-2) and increase of c-PARP and Bcl-2-associcated agonist of cell death (Bad), but also induced autophagy, including increase of autophagic lysosomes and LC3Ⅱ/LC3Ⅰ ratio. …”
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A Review on The Impact of Thermal Stress on Fish Biochemistry by Manoj Kumar Pati, Mohammad Aftabuddin, Prasun Roychowdhury

“…Cumulative effects of thermal stress induce oxidative stress, causing cell death, organ failure, and mortality. Stressors increase the energy demand, prompting changes in hormonal, enzymatic, and biomolecular responses. …”
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