Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis by Li Zhang, Runlin Xing, Zhengquan Huang, Nongshan Zhang, Li Zhang, Xiaochen Li, Peimin Wang

“…In this study, we aimed to investigate whether synovial macrophage pyroptosis did occur and whether this form of cell death should be related to synovitis and fibrosis of KOA. …”
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Obesity-Linked Gut Microbiome Dysbiosis Associated with Derangements in Gut Permeability and Intestinal Cellular Homeostasis Independent of Diet by Ravinder Nagpal, Tiffany M. Newman, Shaohua Wang, Shalini Jain, James F. Lovato, Hariom Yadav

“…Results suggest that non-DIO-associated gut microbiome dysbiosis is associated with changes in the intestinal cell death versus cell proliferation homeostasis and functions to control tight junctions and mucous synthesis-regulating gut permeability.…”
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Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein by N. V. Ivanisenko, L. Hillert, V. A. Ivanisenko, I. N. Lavrik

“…Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC). …”
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Exploring Amanita muscaria (L.) Lam.: Cytotoxic, proapoptotic and antiferroptotic effect of acetone extract on JAR choriocarcinoma cell line by Milojević Sara D., Nikodijević Danijela D., Milutinović Milena G., Kosanić Marijana M., Petrović Nevena N., Jovanović-Krivokuća Milica G., Nacka-Aleksić Mirjana M.

“…The pharmaceutical industry has long focused on nature-derived biologically active compounds to address challenges in cancer treatment, particularly overcoming cancer cell resistance to programmed cell death, including apoptosis and ferroptosis. The cytotoxic effect of Amanita muscaria acetone extract on the JAR choriocarcinoma cell line was evaluated using MTT assay and analysis on two selected programmed cell death pathways. …”
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An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders by Mohammed Alghamdi, Doaa Alasmari, Amjad Assiri, Ehab Mattar, Abdullah A. Aljaddawi, Sana G. Alattas, Elrashdy M. Redwan

“…Citrullination is a normal reaction during cell death. Apoptosis is normally accompanied with a clearance process via scavenger cells. …”
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DLK-dependent axonal mitochondrial fission drives degeneration after axotomy by Jorge Gómez-Deza, Matthew Nebiyou, Mor R. Alkaslasi, Francisco M. Nadal-Nicolás, Preethi Somasundaram, Anastasia L. Slavutsky, Wei Li, Michael E. Ward, Trent A. Watkins, Claire E. Le Pichon

“…We find that mitochondrial fission and resultant cell death are entirely dependent on phosphorylation of dynamin related protein 1 (DRP1) downstream of DLK, revealing a mechanism by which DLK can drive apoptosis. …”
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NDUFA11 may be the disulfidptosis-related biomarker of ischemic stroke based on integrated bioinformatics, clinical samples, and experimental analyses by Sijun Li, Ningyuan Chen, Junrui He, Xibao Luo, Wei Lin

“…BackgroundProgrammed cell death plays an important role in neuronal injury and death after ischemic stroke (IS), leading to cellular glucose deficiency. …”
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Iron(ing) out parkinsonisms: The interplay of proteinopathy and ferroptosis in Parkinson's disease and tau-related parkinsonisms by Maria João da Costa Caiado, Amalia M. Dolga, Wilfred F.A. den Dunnen

“…Thus, we explore the current findings relating to the relationship of parkinsonism proteinopathy (α-synuclein in PD, and tau in PSP/CBD) paralleled to a specific form of cell death, ferroptosis. Ferroptosis is characterised by iron-induced lipid peroxidation and several markers of this pathway have been identified to control intracellular iron fluctuations. …”
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Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer by Xiaolong Liu, Pengxian Tao, He Su, Yulan Li

“…Abstract Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. …”
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RETRACTED: Environmental Impact of Pharmaceutical Pollutants: Synergistic Toxicity of Ivermectin and Cypermethrin by Davide Di Paola, Carmelo Iaria, Fabio Marino, Enrico Gugliandolo, Cristian Piras, Rosalia Crupi, Salvatore Cuzzocrea, Nunziacarla Spanò, Domenico Britti, Alessio Filippo Peritore

“…In conclusion, our study suggests that IVM and CYP show a synergistic effect at common, ineffective concentrations, promoting malformation and cell death in fish development.…”
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Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo by Yanfei Li, Dafa Shi, Haoran Zhang, Xiang Yao, Ke Ren

“…The definitive mechanisms of CI-AKI include contrast medium (CM) nephrotoxicity and CM disturbances in renal blood flow, but how the immune system responds to CM has rarely been mentioned in previous studies, and different cell death pathways have not been clearly distinguished. …”
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Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer by Wei Tan, Fangfang Dai, Qinyu Ci, Zhimin Deng, Hua Liu, Yanxiang Cheng

“…Abstract Background Cuproptosis is a novel form of cell death, acting on the tricarboxylic acid cycle in mitochondrial respiration and mediated by protein lipoylation. …”
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Differential Effects of Alpha-Particle Radiation and X-Irradiation on Genes Associated with Apoptosis by Vinita Chauhan, Matthew Howland, Jeremy Chen, Barbara Kutzner, Ruth C. Wilkins

“…Four days postexposure, cell death was measured by flow cytometry and 84 genes related to apoptosis were analyzed using real-time PCR. …”
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Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells by Eriko Sugano, Namie Murayama, Maki Takahashi, Kitako Tabata, Makoto Tamai, Hiroshi Tomita

“…We show that overexpression of Trx2 reduced cell death induced by both agents when they were present in low concentrations. …”
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Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration by Ping-Wu Zhang, Zi-He Wan, Weifeng Li, Abhishek Vats, Kunal Mehta, Laura Fan, Lingli Zhou, Sean Li, Gloria Li, Casey J. Keuthan, Cynthia Berlinicke, Cheng Qian, Noriko Esumi, Elia J Duh, Donald J. Zack

“…Retinal structure and function were evaluated by spectral-domain optical coherence tomography (SD-OCT) and electroretinography (ERG). Cell death genes were analyzed at 24 and 72 h after LD using the Mouse Pan-Cell Death Pathway PCR Array (88 genes). …”
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Alpha-adrenergic receptor agonists in terms of modern views on glaucoma monitoring and treatment by V.P. Erichev, S.Yu. Petrov, A.V. Volzhanin, D.M. Safonova, T.V. Yaremenko, S.A. Kazaryan

“…Brimonidine prevents ganglionic cell death in glaucomatous optic neuropathy. Several in vitro and in vivo studies describe the mechanism of preventing mitochondrial dysfunction and excitotoxic retinal cell damage in ischemia. …”
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Ferroptosis and its relationship with cancer by Chuanchao Su, Yiwen Xue, Siyu Fan, Xin Sun, Qian Si, Zhen Gu, Jingfei Wang, Runzhi Deng

“…Marked by iron buildup and lipid peroxidation, ferroptosis is a relatively new regulatory cell death (RCD) pathway. Many diseases like cancer, myocardial ischemia-reperfusion injury (MIRI), neurological disorders and acute renal failure (AKI) are corelated with ferroptosis. …”
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Potato Physiological Disorders - Brown Center and Hollow Heart by Chad M. Hutchinson

“…Brown center is characterized by a region of cell death in the pith of the tuber which results in brown tissue. …”
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression by Michala Prause, Christopher Michael Mayer, Caroline Brorsson, Klaus Stensgaard Frederiksen, Nils Billestrup, Joachim Størling, Thomas Mandrup-Poulsen

“…In conclusion, JNK1 mediates INS-1 cell death associated with increased Myc expression. …”
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Physicochemical properties, structure, growth-promoting and antioxidant activities of Glycyrrhiza leaf polysaccharides modified by fermentation by Juan Du, Yuan Wang, Xia Li, Zhalaga, Na Liu, Wenwen Wang, Jingwei Qi, Xiaoli Fan, Xiaoping An

“…FGLP exhibited superior protective effects against lipid peroxidation and cell death induced by AAPH. Graphical Abstract…”
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