Disturbance of Inorganic Phosphate Metabolism in Diabetes Mellitus: Its Relevance to the Pathogenesis of Diabetic Retinopathy by H. Vorum, J. Ditzel

“…Any interruption of optimal ATP production might lead to cell injury and possible cell death, and evidence will be provided herein that such cell death does occur in diabetic retinopathy. …”
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St-N, a novel alkaline derivative of stevioside, reverses docetaxel resistance by targeting lysosomes in vitro and in vivo. by Yanxia Guo, Shikang Wang, Qun Liu, Yan Dong, Yongqing Liu

“…Taken together, these findings demonstrated that St-N reversed docetaxel resistance in vitro and in vivo by destabilizing lysosomal membranes to promote cell death, thus providing a strong rationale for applying St-N in docetaxel-resistant PCa.…”
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Effects of Cisplatin in Neuroblastoma Rat Cells: Damage to Cellular Organelles by Giada Santin, Luigi Scietti, Paola Veneroni, Sergio Barni, Graziella Bernocchi, Maria Grazia Bottone

“…The results obtained show that the cellular organelles are the target of cisPt, so their damage can induce cell death.…”
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In vitro cytotoxicity (irritant potency) of toothpaste ingredients. by Shaira R Kasi, Sanne Roffel, Mutlu Özcan, Susan Gibbs, Albert J Feilzer

“…The compound concentration resulting in 50% cell death (EC50) and 10% cell death (EC10) was determined by the MTT assay. …”
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Pharmacological targeting of caspase-8/c-FLIPL heterodimer enhances complex II assembly and elimination of pancreatic cancer cells by Corinna König, Nikita V. Ivanisenko, Vladimir A. Ivanisenko, Dagmar Kulms, Inna N. Lavrik

“…However, the effects of FLIPinB action in combination with other cell death inducers have only just begun to be elucidated. …”
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Yeast as a Tool to Study Signaling Pathways in Mitochondrial Stress Response and Cytoprotection by Maša Ždralević, Nicoletta Guaragnella, Lucia Antonacci, Ersilia Marra, Sergio Giannattasio

“…The crucial role of mitochondria in cell death is well recognized. Mitochondrial dysfunction has been associated with the death process and the onset of numerous diseases. …”
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Clinical and molecular response to alpha1‐oleate treatment in patients with bladder cancer by Farhan Haq, Samudra Sabari, Jaromir Háček, Antonín Brisuda, Ines Ambite, Michele Cavalera, Parisa Esmaeili, Murphy Lam Yim Wan, Shahram Ahmadi, Marek Babjuk, Catharina Svanborg

“…Uptake of alpha1‐oleate by the tumor triggered rapid shedding of tumor cells into the urine and cell death by an apoptosis‐like mechanism. RNA sequencing of tissue biopsies confirmed the activation of apoptotic cell death and strong inhibition of cancer gene networks, including bladder cancer related genes. …”
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Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway by Jing Chen, Jie Wu, Xiang Chen, Qian Tao, Nian Liu, Cong Peng, Can Lu, Qiuqiu Li

“…This resulted in apoptosis, pyroptosis, and immunogenic cell death in tumor cells by Clo. Furthermore, Clo-induced GSDME-mediated pyroptosis partly assists in activating T cell immunity via CCL5 and CXCL10. …”
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Multiorganelle Localization of Metallated Phthalocyanine Photosensitizer in Colorectal Cancer Cells (DLD-1 and CaCo-2) Enhances Efficacy of Photodynamic Therapy by Palesa Rose Sekhejane, Nicolette Nadene Houreld, Heidi Abrahamse

“…In conclusion, ZnPcSmix showed the ability of inducing apoptotic cell death features in PDT treated cells.…”
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Human cytomegalovirus RNA2.7 inhibits ferroptosis by upregulating ferritin and GSH via promoting ZNF395 degradation. by Mingyi Xu, Shan Ruan, Jingxuan Sun, Jianming Li, Dan Chen, Yanping Ma, Ying Qi, Zhongyang Liu, Qiang Ruan, Yujing Huang

“…The effect of RNA2.7 on other forms of cell death is still unclear. In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy by Zhichao Wang, Yuqi Tang, Quan Li

“…Abstract The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms. Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity. …”
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The DNA Replication Stress Hypothesis of Alzheimer’s Disease by Yuri B. Yurov, Svetlana G. Vorsanova, Ivan Y. Iourov

“…We propose that unscheduled and incomplete DNA replication (replication stress) destabilizes (epi)genomic landscape in the brain and leads to DNA replication “catastrophe” causing cell death during the S phase (replicative cell death). …”
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Differential Toxicity of DNA Adducts of Mitomycin C by Jill Bargonetti, Elise Champeil, Maria Tomasz

“…This difference in the cell death pathways activated by the MC and DMC is attributed to differential signaling by the DNA adducts of DMC. …”
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The Aging GABAergic System and Its Nutritional Support by Demetra J. Mills

“…Loss of calcium regulation associated with aging can lead to an excitatory cell state, primarily in the mitochondria and nerve cells, which can ultimately lead to cell death if not kept in check. A decline in GABAergic function can also be specifically tied to declines in progesterone, allopregnanolone, and DHEA levels associated with aging. …”
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Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice by Sonja Mendritzki, Saskia Schmidt, Teresa Sczepan, Xin-Ran Zhu, Daniel Segelcke, Hermann Lübbert

“…In addition, these mice exhibit astrocytic cell death in the spinal cord, accompanied by extensive gliosis and microglial activation. …”
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The mechanism underlying metastasis in triple-negative breast cancer: focusing on the interplay between ferroptosis, epithelial-mesenchymal transition, and non-coding RNAs by Ziyi Chen, Yi Zhao, Yi Zhao

“…Ferroptosis is an iron-dependent cell death form, and changes its key factor to affect the proliferation and metastasis of TNBC. …”
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Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis. by Katy Poncin, Samantha A McKeand, Hayley Lavender, Kacper Kurzyp, Odile B Harrison, Annabell Roberti, Charlotte Melia, Errin Johnson, Martin C J Maiden, David R Greaves, Rachel Exley, Christoph M Tang

“…Instead, the gonococcal Neisseria autolysis peptides (Naps) promote autolytic cell death when bacteria enter the stationary phase of growth. …”
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An Insight of Vitamin E as Neuroprotective Agents by Hui-Min Yap, Kwan-Liang Lye

“…Oxidative stress has a role in the modulation of critical cellular functions, such as apoptosis program activation, ion transport and calcium mobilization which lead to cell death. Many studies were conducted to prevent neuronal cell death caused by oxidative stress through administration of free radical scavenging antioxidant, such as vitamin E. …”
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Hyperprogressive disease induced by PD-1 inhibitor monotherapy in lung adenocarcinoma with HER2 exon 20 insertion: report of two cases and review of literature by Guangjian Yang, Linyan Tian, Yan Wang

“…Abstract Monotherapy with anti-programmed cell death protein 1 (PD-1) monoclonal antibody has been approved for the treatment of advanced non-small cell lung cancer with positive programmed cell death-ligand 1 (PD-L1) expression and oncogene wild type, which revealed survival benefit compared with chemotherapy. …”
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Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice by Seung Hee Choi, Jaechan Leem, In-Kyu Lee

“…Gemigliptin attenuated cisplatin-induced apoptotic cell death, as assessed by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling and Western blot analysis in the kidneys. …”
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