Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus by Fangyuan Yang, Yi He, Zeqing Zhai, Erwei Sun

“…This review briefly discusses different forms of programmed cell death pathways and lay particular emphasis on inflammatory cell death pathways such as NETosis, pyroptosis, and necroptosis and their roles in the inflammatory and immune responses in SLE.…”
Get full text

Multifaceted roles of ninjurin1 in immunity, cell death, and disease by Lili Zhu, Yunfei Xu, Yunfei Xu

Subjects: Get full text

GSK-3𝜷: A Bifunctional Role in Cell Death Pathways by Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, Dinesh Thotala

Get full text

DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma by Ze Qian, Yifan Jiang, Yacong Wang, Yu Li, Lin Zhang, Xiaofeng Xu, Diyu Chen

“…Sustained overexpression of ACADS not only suppressed the proliferation, migration, and invasion of HCC cells but also promoted immunogenic cell death (ICD) via the upregulation of calreticulin. …”
Get full text

Annexin A5–Functionalized Nanoparticle for Multimodal Imaging of Cell Death by Rui Zhang, Miao Huang, Min Zhou, Xiaoxia Wen, Qian Huang, Chun Li

“…Techniques for visualizing cell death can provide noninvasive assessment of both disease states and response to therapeutic intervention. …”
Get full text

Silver nanoparticle induced immunogenic cell death can improve immunotherapy by Ara Sargsian, Xanthippi Koutsoumpou, Hermon Girmatsion, Can Egil, Kiana Buttiens, Carla Rios Luci, Stefaan J. Soenen, Bella B. Manshian

Subjects: Get full text

Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

“…Recent Findings. Beta cell death is the final event in a series of mechanisms that, up to date, have not been entirely clarified; it represents the pathophysiological mechanism in the natural history of diabetes mellitus. …”
Get full text

“Dead Cells Talking”: The Silent Form of Cell Death Is Not so Quiet by Richard Jäger, Howard O. Fearnhead

“…After more than twenty years of research, the molecular events of apoptotic cell death can be succinctly stated; different pathways, activated by diverse signals, increase the activity of proteases called caspases that rapidly and irreversibly dismantle condemned cell by cleaving specific substrates. …”
Get full text

Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

“…Summary: In multiple sclerosis (MS), inflammation of the central nervous system results in demyelination, neuroaxonal injury, and cell death. However, the molecular signals responsible for injury and cell death in neurons are not fully characterized. …”
Get full text

Microscopic Photosensitization: A New Tool to Investigate the Role of Mitochondria in Cell Death by May-Ghee Lum, Tetsuhiro Minamikawa, Phillip Nagley

“…Active involvement of mitochondria in cell death has been well-documented, but local apoptotic signaling between subsets of mitochondria has been poorly explored to date. …”
Get full text

Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice by Daniel E. Maidana, Sara Pastor Puente, Catherine Wang, Shivam Chandra, Lucia Gonzalez-Buendia, Eleftherios Paschalis Ilios, Andrius Kazlauskas, Demetrios G. Vavvas

“…Notably, late-stage analysis demonstrates higher photoreceptor cell death in the TS approach, paralleled by increased subretinal infiltration of CD11b + cells. …”
Get full text

The Interplay Between Viral Infection and Cell Death: A Ping-Pong Effect by Alireza Nourazarian, Hadi Yousefi, Cigir Biray Avci, Behrouz Shademan, Emad Behboudi

“…Programmed cell death (PCD) is a well-studied cellular mechanism that plays a critical role in immune responses, developmental processes, and the maintenance of tissue homeostasis. …”
Get full text

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice by José Belizário, Luiz Vieira-Cordeiro, Sylvia Enns

“…Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome based on genetic analysis of knockout mice.…”
Get full text

Correction: Silver nanoparticle induced immunogenic cell death can improve immunotherapy by Ara Sargsian, Xanthippi Koutsoumpou, Hermon Girmatsion, Can Egil, Kiana Buttiens, Carla Rios Luci, Stefaan J. Soenen, Bella B. Manshian

Get full text

Advances in non-apoptotic regulated cell death: implications for malignant tumor treatment by Yizheng Zhang, Shiqi Yi, Mingyuan Luan

Subjects: “…regulated cell death…”
Get full text

Bio-mimetic strategies to re-activate apoptotic cell death for cancer treatments by Andrea Venerando, Denise Lovison, Rossella De Marco

Get full text

The Bloom Syndrome Protein BLM Is Selectively Cleaved during Apoptotic Cell Death by Oliver Bischof, Sanjeev Galande, Terumi Kohwi-Shigematsu, Judith Campisi, Anne Dejean

Get full text

Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells by Claire Pecqueur, Lisa Oliver, Kristell Oizel, Lisenn Lalier, François M. Vallette

Get full text

Overview of Cell Death Mechanisms Induced by Rose Bengal Acetate-Photodynamic Therapy by Elisa Panzarini, Valentina Inguscio, Luciana Dini

“…Indeed, RBAc exerts long-term phototoxicity through activation of both caspase-independent and- dependent apoptotic pathways and autophagic cell death. In particular, this latter cell death type may promote cell demise when apoptotic machinery is defective. …”
Get full text

Multiple programmed cell death patterns predict the prognosis and drug sensitivity in gastric cancer by Qiying Song, Shihe Liu, Di Wu, Aizhen Cai

Subjects: Get full text