The mutational spectrum of NRAS gene discovers a novel frameshift mutation (E49R) in Saudi colorectal cancer patients by Mahmood Rasool, Absarul Haque, Mohammed Alharthi, Abdulrahman Sibiany, Mohammed Saad Alamri, Samer Mohammed Hassan Alqarni, Irfan A. Rather, Adeel G. Chaudhary, Sajjad Karim, Peter Natesan Pushparaj

“…Abstract Colorectal cancer (CRC) is a major health problem the world face currently and one of the leading causes of death worldwide. CRC is genetically heterogeneous and multiple genetic aberrations may appear on course of the disease throughout patient’s lifetime. …”
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Impact of patient compliance with inhaler therapy on chronic obstructive pulmonary disease severity: a rural tertiary care perspective by Nandakishore K. S., Preethiraj Ballal, Anirudha Katipalla, Shruthi Rai P., Supreetha T., Dixith T., Sanjay Srinivas, Shree Dhanusha, Pramod Pujar, Sushmitha Sudeesh, Vignesh T. M.

“…Abstract Background Inhaled medications have been the cornerstone of treatment for the exacerbations as well as stable chronic obstructive pulmonary disease (COPD) which is one of the leading cause of deaths in the recent times. Inadequate knowledge on handling of inhalers leads to noncompliance which in turn results in increased hospital visits limelighting the negative impact on the morbidity status. …”
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Public knowledge of early stroke symptoms in the Vilnius region by A. Atkočiūnas, M. Mačionytė, R. Mameniškienė

“…Stroke remains one of the most common causes of death and disability in the world. The evident decline in disabling outcomes can be attributed to the increasing use of reperfusion therapies. …”
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Improving the predictive capability of Framingham Risk Score for the risk of myocardial infarction based on coronary artery calcium score in healthy Singaporeans by Ching Yee Ivory Yeo, John Carson Jr Allen, Weiting Huang, Wei Ying Tan, Siew Ching Kong, Khung Keong Yeo

“…Introduction: Cardiovascular disease was the top cause of deaths and disability in Singapore in 2018, contributing extensively to the local healthcare burden. …”
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Perceptual Disturbances and Disorders in the ICD-11: An Overview and a Proposal for Systematic Classification by Berthold Langguth, Michael Landgrebe, Dirk De Ridder

“…The International Classification of Diseases (ICD) has been developed and edited by the World Health Organisation and represents the global standard for recording health information and causes of death. The ICD-11 is the eleventh revision and came into effect on 1 January 2022. …”
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CT Findings and Mortality in Patients with Nontraumatic Intracerebral Hemorrhage by Pedro Juan Barrios Fuentes, José Luis Bernal Muñoz, Marcos Félix Osorio Pagola, Anagalys Ortega Alvelay, Liliana Teresa Caneiro González

“…<strong>Background: </strong>Cerebrovascular disease is among the leading causes of death in developed countries. Intracerebral hemorrhage contributes a significant number of these deaths. …”
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Investigation of non-alcoholic steatohepatitis in labidochromis caeruleus and xiphophorus hellerii by Mustafa Ünal Boyraz, Muhammet Yaşar Dörtbudak, Muhammet Bahıttin Dörtbudak

“…The aim of this study, upon the discovery that these species died by showing various clinical signs in optimum conditions and standard feding conditions, was to investigate the causes of death and to determine the problems that may be encountered in the field.…”
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Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization by Yanhong Liu, Yunqi Hua, Xiaoe Jia

“…Background: Stroke causes substantial death and disability worldwide, challenging healthcare systems and impacting patients' lives. …”
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VCAM-1 Promotes Angiogenesis of Bone Marrow Mesenchymal Stem Cells Derived from Patients with Trauma-Induced Osteonecrosis of the Femoral Head by Regulating the Apelin/CCN2 Pathway by Yiming Shao, Lei Sun, Baodong Ma, Ranran Jin, Yueyao Ban, Ruibo Li, Jianfa Wang, Hongkai Lian, Han Yue

“…Trauma-induced osteonecrosis of the femoral head (TI-ONFH) is a pathological process in which the destruction of blood vessels supplying blood to the femoral head causes the death of bone tissue cells. Vascular cell adhesion molecule 1 (VCAM-1) has been shown to have potent proangiogenic activity, but the role in angiogenesis of TI-ONFH is unclear. …”
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The link between spreading depolarization and innate immunity in the central nervous system by Kadir Oguzhan Soylu, Muge Yemisci, Hulya Karatas

“…Abstract Spreading depolarization (SD) is a complex event that induces significant cellular stress in the central nervous system, leading to a robust inflammatory response without causing cell death in healthy tissues which may be called as neuro-parainflammation. …”
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Epidemiology of Pancreatic Carcinoma in Canada: 1931 to 1985 by Anthony Ayiomamitis

“…It is among the 10 leading causes of death from cancer and the 10 leading sites of newly diagnosed cases for a number of age groups. …”
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A Model Study of Building Seismic Damage Information Extraction and Analysis on Ground-Based LiDAR Data by Fan Yang, Xintao Wen, Xiaoshan Wang, Xiaoli Li, Zhiqiang Li

“…Earthquake disasters can have a serious impact on people’s lives and property, with damage to buildings being one of the main causes of death and injury. A rapid assessment of the extent of building damage is essential for emergency response management, rescue operations, and reconstruction. …”
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IDMPF: intelligent diabetes mellitus prediction framework using machine learning by Leila Ismail, Huned Materwala

“…Diabetes is a chronic disease and one of the 10 causes of death worldwide. It is expected that the total number of diabetes will be 700 million in 2045; a 51.18% increase compared to 2019. …”
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A Review on The Impact of Thermal Stress on Fish Biochemistry by Manoj Kumar Pati, Mohammad Aftabuddin, Prasun Roychowdhury

“…Cumulative effects of thermal stress induce oxidative stress, causing cell death, organ failure, and mortality. Stressors increase the energy demand, prompting changes in hormonal, enzymatic, and biomolecular responses. …”
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Congenital Heart Disease Diagnosed Prenatally in Cienfuegos. 10 Year Study by Nancy González Vales, Rossana Isabel Jiménez Arias, María Antonia Ocaña, Nicolás Ramón Cruz Pérez, Julio César Martínez Santana, Jan Oneil González Ramos

“…<br /><strong>Conclusions:</strong> congenital heart disease currently continues to be one of the main causes of death in the first year of life.…”
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Knowledge and Attitudes of the Inhabitants of a Rural Canton about the Prevention of Colorectal Cancer by Carlos David Castañeda Guillot, Blanca Cristina Estrella López, Diego Fernando Vaca Sánchez

“…<strong>Foundation:</strong> colorectal cancer is one of the main causes of death from cancer in Ecuador, both in men and women. …”
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Molecular identification of Newcastle disease virus isolated on the poultry farm of the Moscow Oblast in summer of 2022 by А. А. Treshchalina, А. А. Rtishchev, Е. Yu. Shustova, А. V. Belyakova, A. S. Gambaryan, Е. Yu. Boravleva

“…It was found that the average death time of developing chicken embryos, infected with a minimum infectious dose, was 52 hours, which is typical for the velogenic pathotype. The virus caused 100% death in six-week-old chickens after oral infection and 100% death in all contact chickens, including those kept in cages at a distance, which proves the high level of pathogenicity and contagiousness of the recovered isolate and its ability to transmit both via fecal-oral and aerosols–borne routes. …”
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Therapeutic Adherence in Patients with Arterial Hypertension by Liens Hernández Quintero, Diana Amelia Crespo Fernández, Liliet Trujillo Cruz, Liliana María Hernández Quintero, Marcia Azcuy Pérez

“…<strong>Background:</strong> arterial hypertension is presented worldwide as one of the main causes of death and disability. Lack of adherence to treatment is one of this disease great problems. …”
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Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Neuroinflammation and neuronal cell death are leading causes of death in the elderly and underlie various neurodegenerative diseases. …”
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Predatory bacteria can intensify lung-injury in a multidrug-resistant Acinetobacter baumannii pneumonia model in rat by Zeinab Mohsenipour, Farzaneh Kianian, Behnaz Jahanbin, Hamid Reza Abtahi, Tooba Ghazanfari, Maryam Edalatifard, Saeid Amanpour, Mikael Skurnik, Parya Arazi, Mohammad Mehdi Feizabadi, Mohammad Mehdi Feizabadi

“…IntroductionRespiratory tract infection caused by antibiotic-resistant bacteria are one of the most important causes of death worldwide. Therefore, in this study, we investigated the possibility of using predatory bacteria to improve the Acinetobacter baumannii pneumonia model in rat.MethodsMultidrug-resistant (MDR) A. baumannii clinical strain was used to induce pneumonia. …”
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