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601
Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy
Published 2020-06-01“…HF and its concomitant diagnoses, as well as all CM diagnoses, were collected from the national inpatient, outpatient, and cause of death registries. Risk estimates were calculated by Cox‐proportional hazards models while adjusting for potential confounders. …”
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602
Behavioral risk factors and socioeconomic inequalities in ischemic heart disease mortality in the United States: A causal mediation analysis using record linkage data.
Published 2024-09-01“…<h4>Background</h4>Ischemic heart disease (IHD) is a major cause of death in the United States (US), with marked mortality inequalities. …”
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603
Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway
Published 2020-01-01“…Brain injury is the leading cause of death following cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). …”
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604
The Explo’Santé mixed methods protocol: an interventional research school health promotion project in France
Published 2025-01-01“…Abstract Background According to WHO, “noncommunicable diseases (NCDs) kill 41 million people” annually, as the primary cause of death globally. WHO’s Global Action Plan for the prevention and control of NCDs 2013–2020 (extended) tackles this issue and its implications regarding inequalities between countries and populations. …”
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605
Relationship between iron deficiency and severity of tuberculosis: Influence on T cell subsets
Published 2025-02-01“…Summary: Tuberculosis (TB) remains a leading cause of death globally, with nearly half of TB patients experiencing iron deficiency. …”
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606
Fabrication and Characterization of Chitosan-Polyethylene Glycol (Ch-Peg) Based Hydrogels and Evaluation of Their Potency in Rat Skin Wound Model
Published 2021-01-01“…Thermal burns are a major cause of death and suffering around the globe. They can cause debilitating, life-altering injuries as well as lead to significant psychological and financial consequences. …”
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607
Clinical Characteristics and Outcomes of Deep Vein Thrombosis in Relation to Location: A Retrospective Analysis Study
Published 2025-01-01“…Background: Deep vein thrombosis (DVT) is a leading cause of death disability. DVT can be classified based on the location and extent of the clot into isolated distal DVT (iDDVT), isolated proximal DVT (iPDVT), or mixed DVT. …”
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608
Causes and determinants of infant mortality using verbal autopsy and social autopsy methods in a rural population of Odisha: a community-based matched case-control study
Published 2025-01-01“…We selected an equal number of alive infants matched with cases in a 1:1 ratio with regard to age, gender and residential address.Outcome measures We conducted the verbal autopsy using the Sample Registration System verbal autopsy tool, where the cause of death ascertainment was done by two independently trained physicians followed by adjudication by one senior trained physician in case of conflicts. …”
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609
Hubungan Kadar Laktat Dehidrogenase dengan Stadium Limfoma Maligna Non Hodgkin di Rumah Sakit Dr. M. Djamil Padang periode Desember 2009 sampai Maret 2013
Published 2014-05-01“…Changing patterns of disease can be seen from the increased incidence of cancer as a cause of death in Indonesia in the last 10 years, ie from 12th to 6th order. …”
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610
Early onset neonatal bloodstream infections in South African hospitals
Published 2025-01-01“…Abstract Background Neonatal sepsis is a leading cause of death in low- and middle- income countries (LMIC). …”
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611
Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation
Published 2025-01-01“…Obesity, the fifth leading cause of death globally and linked to chronic low-grade inflammation and development of numerous severe pathologies, is a major public health problem. …”
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612
Peripheral versus central cannulation of VA-ECMO for primary graft dysfunction after heart transplantation: A systematic review and meta-analysis
Published 2025-02-01“…Background: Severe primary graft dysfunction (PGD) after heart transplantation (HT) is a major cause of death and requires veno-arterial extracorporeal membrane oxygenation (VA-ECMO). …”
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613
Is the Use of Tourniquets More Advantageous than Other Bleeding Control Techniques in Patients with Limb Hemorrhage? A Systematic Review and Meta-Analysis
Published 2025-01-01“…<i>Background and Objectives:</i> Trauma, particularly uncontrolled bleeding, is a major cause of death. Recent evidence-based guidelines recommend the use of a tourniquet when life-threating limb bleeding cannot be controlled with direct pressure. …”
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614
Estimating Trends in Cardiovascular Disease Risk for the EXPOSE (Explaining Population Trends in Cardiovascular Risk: A Comparative Analysis of Health Transitions in South Africa a...
Published 2025-01-01“… BackgroundCardiovascular diseases (CVDs) are the leading cause of death globally. Demographic, behavioral, socioeconomic, health care, and psychosocial variables considered risk factors for CVD are routinely measured in population health surveys, providing opportunities to examine health transitions. …”
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615
Excessive activation of JAK-STAT signaling contributes to inflammation induced by acute Vibrio infection in shrimp
Published 2025-12-01“…Uncontrolled immune responses resulting from overactivated cellular signaling pathways, leading to inflammation and tissue injury, are a major cause of death in pathogen-infected individuals. This phenomenon has been well studied in mammals but is less explored in invertebrates. …”
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616
Smart design in biopolymer-based hemostatic sponges: From hemostasis to multiple functions
Published 2025-03-01“…Uncontrolled hemorrhage remains the leading cause of death in clinical and emergency care, posing a major threat to human life. …”
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617
E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis
Published 2025-04-01“…Introduction: Tobacco use is the leading cause of death in the U.S., and American Indian/Alaska Native people have high rates of tobacco-related diseases. …”
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618
Radiation to all macroscopic sites of tumor permits greater systemic antitumor response to in situ vaccination
Published 2023-01-01“…Tumor growth, overall survival, and cause of death were measured. Flow cytometry was used to evaluate immune population changes in both tumors.Results Abscopal effects of local ISV were amplified by delivering as little as 2–6 Gy of EBRT to the secondary tumor. …”
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619
Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor‐Associated Macrophage
Published 2025-01-01“…Abstract Liver metastasis is the major cause of death in colorectal cancer (CRC) due to the lack of effective treatment. …”
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620
Occupational exposures and coronary heart disease in the Hamburg City Health Study (HCHS) – a cross-sectional study
Published 2025-01-01“…Abstract Background Coronary heart disease (CHD) is the leading cause of death among adults in Germany. There is evidence that occupational exposure to particulate matter, noise, psychosocial stressors, shift work and high physical workload are associated with CHD. …”
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