Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for... by Joan G Meeder, Frits H M Van Osch, Robert T A Willemsen, Braim M Rahel, Lisa D S Frenk, Cees B de Vos, Fabiana G Prestigiacomo, Marcel J W Janssen, Arnoud W van 't Hof

“…Introduction Ischaemic heart disease is the single most common cause of death worldwide. Traditionally, distinguishing patients with cardiac ischaemia from patients with less alarming disease, in prehospital triage of chest pain, is challenging for both general practitioners and ambulance paramedics. …”
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Assessing the Risk Factors of Violent and Non-violent Suicide Attempt Methods: A Population-based Cross-sectional Study by Amin Moradi, Ehsan Mosafarkhani, Fateme Nikbakht, Zahra Amiri, Ali Vafaee Najar

“…It is the fourth-leading cause of death among young people between the ages of 15 and 29. …”
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Using verbal and social autopsy approaches to understand why neonates die in rural settings: a case study of a remote rural district in Uganda by Peter Waiswa, Rornald Muhumuza Kananura, Dinah Amongin, Joseph Akuze, Jacquellyn Nambi Ssanyu, Felix Kizito

“…The primary causes of death were birth asphyxia (42.4%), low birth weight/prematurity (18.6%), other perinatal causes (12.8%) and neonatal sepsis (9.3%). …”
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Maternal death audit in Rwanda 2009–2013: a nationwide facility-based retrospective cohort study by Jeroen van Dillen, Felix Sayinzoga, Leon Bijlmakers, Fidele Ngabo, Victor Mivumbi, Koos van der Velden

“…Health system failures were identified as the main responsible factor for the majority of cases (61.0%); in 30.3% of the cases, the main factor was patient or community related.Conclusions The facility-based maternal death audit approach has helped hospital teams to identify direct and indirect causes of death, and their contributing factors, and to make recommendations for actions that would reduce the risk of reoccurrence. …”
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Nursing knowledge in cardio-oncology: results of an international learning needs-assessment survey by Anecita Fadol, Geraldine Lee, Valerie Shelton, Kelly C. Schadler, Asma Mohammed Younus, Mary Stuart, Lisa Nodzon, Edith Pituskin

“…In some cancer types, cardiovascular disease now competes with recurrent cancer as the cause of death. Traditional care models, in which the cardiologist or oncologist assess patients individually, do not address complex cancer and cardiovascular needs. …”
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ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data by P.P. Zinych, V.M. Pushkarev, N.I. Levchuk, M. Tronko

“…Metastases are the leading cause of death from malignant tumors. The metastatic process involves the exit of cancer cells from the primary tumor into the blood or other transport system, colonization and proliferation in a distant organ. …”
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Control of hypercapnia and mortality in home mechanical ventilation: the population-based DISCOVERY study by Andreas Palm, Magnus Ekström, Össur Emilsson, Karin Ersson, Mirjam Ljunggren, Josefin Sundh, Ludger Grote

“…Study design and methods Population-based cohort study of adult patients starting HMV in the Swedish Registry for Respiratory Failure (Swedevox) during 1996–2022 cross-linked with the National Cause of Death registry. Mortality risk factors were analysed using crude and multivariable Cox regression models, including adjustments for anthropometrics, comorbidities, the underlying diagnosis causing chronic hypercapnic respiratory failure (CRF) and the control of hypercapnia (PaCO2 ≤6.0 kPa) at follow-up. …”
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Dynamic Changes in Parameters of Complete Blood Count Predict Disease Severity and Prognosis in Patients with COVID-19; A Prospective Study by Toktam Alirezaei, Mahdi Baratnia, Rama Bozorgmehr, Yasamansadat Keshmiri, Faezeh Ebrahimpour, Maryam Arefnia, Mohammadali Ghodsirad

“…Background: The pandemic of the coronavirus disease 2019 (COVID-19) is a major cause of death worldwide; thus, disease prediction is important. …”
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Extrapolating Prognostic Factors of Primary Curative Resection to Postresection Recurrences Hepatocellular Carcinoma Treatable by Radiofrequency Ablation by Hui Ma, Zhongchen Li, Jia Yuan, Lan Zhang, Xiaoying Xie, Xin Yin, Rongxin Chen, Zhenggang Ren

“…Recurrence after curative resection for hepatocellular carcinoma (HCC) is a major cause of death from this disease. Factors of primary curative resection are available and potential in the prognosis of follow-up treatment. …”
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Sex differences in the time trends of sepsis biomarkers following polytrauma by Cédric Niggli, Philipp Vetter, Jan Hambrecht, Hans-Christoph Pape, Ladislav Mica

“…Abstract Sepsis is a major cause of death in polytrauma patients, with delayed antibiotics increasing mortality. …”
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Pola Kejadian ISPA pada Balita di Wilayah Kerja Puskesmas Anak Air Padang Tahun 2012 by Aidil Rahman Novesar, Eryati Darwin, Finny Fitry Yani

“…</p><p>Kata kunci: ISPA, bayi, pola kejadian, distribusi</p><p> </p><p>Abstract<br />Acute Respiratory Infection (ARI) is still an issue regarding the importance of public health, because it cause high death rates, in a scale 1 from 4. Every child was estimated having 3 - 6 episodes of ARI every year. …”
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The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling by Zhenyu Zhang, Yina Gao, Yuanyuan Qian, Bowen Wei, Kexin Jiang, Zhiwei Sun, Feifan Zhang, Mingming Yang, Salem Baldi, Xiaoqi Yu, Yunfei Zuo, Shuangyi Ren

“…Abstract Liver metastasis is a common cause of death in colorectal cancer (CRC) patients, but epigenetic remodeling and metabolic reprogramming for CRC liver metastasis remain unclear. …”
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Gut mycobiome alterations and network interactions with the bacteriome in patients with atherosclerotic cardiovascular disease by Guangming Su, Ping Huang, Dan Liu, Guorui Xing, Ruochun Guo, Shenghui Li, Shao Fan, Lin Cheng, Qiulong Yan, Wei Yang

“…Our findings offer a thorough understanding of the link between the gut mycobiome and ACVD progression, which is vital for directing future therapeutic research.IMPORTANCEACVD is a leading cause of death and morbidity worldwide. While the role of the gut microbiome in ACVD development is recognized, the contribution of the gut mycobiome remains largely unexplored. …”
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The Link between Overweight/Obesity and Noncommunicable Diseases in Ethiopia: Evidences from Nationwide WHO STEPS Survey 2015 by Bedilu Alamirie Ejigu, Fentanesh Nibret Tiruneh

“…Noncommunicable diseases (NCDs) are the leading cause of death worldwide. Each year, 15 million adults die from NCDs; more than 85% of these premature deaths occur in low- and middle-income nations. …”
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Private sector delivery of care for maternal and newborn health: trends over a decade in the Indian state of Bihar by G. Anil Kumar, Sibin George, Moutushi Majumder, S. Siva Prasad Dora, Md Akbar, Tanmay Mahapatra, Rakhi Dandona

“…Birth asphyxia was the leading cause of death in 2016 (37.8%) and 2020–2021 (33.9%) followed by preterm delivery and neonatal pneumonia; a statistically significant reduction was seen in meningitis/sepsis between 2016 and 2020–2021 (77.8%; 95% CI = − 145.4 to − 10.1). …”
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Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival by Bárbara Mora-Lagos, María Elena Reyes, Lorena Lobos-Gonzalez, Matías del Campo, Kurt Buchegger, Louise Zanella, Ismael Riquelme, Carmen Gloria Ili, Priscilla Brebi

“…Abstract Background Gastric cancer (GC) is a significant cancer-related cause of death worldwide. GC’s most used chemotherapeutic regimen is based on platinum drugs such as cisplatin (CDDP). …”
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Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006. by Gamji Rabiu Abu-Ba'are, Osman Wumpini Shamrock, Darcey Rodriguez, George Rudolph Kofi Agbemedu, LaRon E Nelson

“…Among adolescents, HIV/AIDs remains a significant cause of death globally [1-4]. Given the unique stages in human development, adolescents have been shown to fall within a sexually active phase. …”
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Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia by Elena Markaryan, Matthew Dodd, Stephen Allen, Carol Howell, Angela Allen, Paul Rahden, Abdoulie Fatty, Momodou Lamin Jobarteh, Abdoulwahab Sallah, Ebrahim Jaiteh, Doreen Umoh, Fanta Bass, Radovan Hnatič

“…Background Diarrhoea remains a leading cause of death in children. An intestinal adsorbent may reduce diarrhoea duration and severity.Methods Randomised controlled feasibility trial with two phases: phase 1 (0–4 hours and double-blind) and phase 2 (up to 5 days and open-label). 50 children aged 6–59 months with acute diarrhoea presenting with no or some dehydration to the emergency paediatric unit and outpatient clinic at Edward Francis Small Teaching Hospital, Banjul, The Gambia were randomised to either standard treatment (oral rehydration fluid and zinc) or standard treatment with polymethylsiloxane polyhydrate for up to 5 days.Results Recruitment was completed in 7 months. …”
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Bone Marrow-Derived Multipotent Stromal Cells Attenuate Inflammation in Obliterative Airway Disease in Mouse Tracheal Allografts by Alicia Casey, Fabian Dirks, Olin D. Liang, Hakima Harrach, Katharina Schuette-Nuetgen, Kristen Leeman, Carla F. Kim, Craig Gerard, Meera Subramaniam

“…Obliterative bronchiolitis (OB) remains the most significant cause of death in long-term survival of lung transplantation. …”
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Tuberculosis healthcare service disruptions during the COVID-19 pandemic in Brazil, India and South Africa: A model-based analysis of country-level data. by Abigail K de Villiers, Muhammad Osman, Claudio J Struchiner, Anete Trajman, Dheeraj Tumu, Vaibhav V Shah, Guilherme L Werneck, Layana C Alves, Megha Choudhary, Sunita Verma, Sanjay K Mattoo, Sue-Ann Meehan, Urvashi B Singh, Anneke C Hesseling, Florian M Marx

“…Tuberculosis (TB) is the leading infectious disease cause of death worldwide. In recent years, stringent measures to contain the spread of SARS-CoV-2 have led to considerable disruptions of healthcare services for TB in many countries. …”
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