Anxiety-like behavior and altered hippocampal activity in a transgenic mouse model of Fabry disease by Kai Kummer, Jeiny Luna Choconta, Marie-Luise Edenhofer, Archana Bajpai, Gopuraja Dharmalingam, Theodora Kalpachidou, David A. Collier, Michaela Kress

“…Conclusions: Our study highlights transcriptional and functional alterations in non-neuronal and neuronal cell clusters in the hippocampus of FD mice, which are suggested to be causally related to anxiety-like behavior developing as a consequence of FD pathology in mouse models of the disease and in patients.…”
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Early-life cognitively stimulating activities and late-life cognitive function in the St. Louis Baby Tooth Later Life Health Study by Andrea L. Roberts, Xinye Qiu, Kaleigh A. McAlaine, Laura T. Germine, Ran S. Rotem, Marc G. Weisskopf

“…If the associations we found are causal, increasing cognitively stimulating activities in the late teen years among those with very few activities may benefit late life cognitive health.…”
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Drug-Induced Liver Injuries (Clinical Guidelines for Physicians) by Vladimir T. Ivashkin, Andrey Yu. Baranovsky, Karina L. Raikhelson, Lyudmila K. Palgova, Marina V. Maevskaya, Elina A. Kondrashina, Natalya V. Marchenko, Tatyana P. Nekrasova, Igor G. Nikitin

“…A section on the assessment of causal relationships in the diagnosis of DILI is presented; the practical value of using the CIOMS-RUCAM scale is shown. …”
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Bifidobacterium animalis ssp. lactis BX-245-fermented milk alleviates tumor burden in mice with colorectal cancer by Chengcong Yang, Musu Zha, Lu Li, Jiaqi Qiao, Lai-Yu Kwok, Dandan Wang, Yongfu Chen

“…The current results are preliminary, and further confirmation is necessary to establish the causal relationship among probiotic milk, changes in gut microbiota, and disease alleviation.…”
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Dias-Logan syndrome with a p.Leu360Profs*212 heterozygous pathogenic variant of in a Chinese patient: A case report by Yizhuo Shu, Xiaoling Chen, Zhuoqun Wei, Chunyue Chen

“…Consequently, trio-WES analysis (parents and child) was conducted as it can identify potential new causal variants in the offspring. So far, a comprehensive understanding of the phenotypic spectrum of Dias-Logan syndrome and the impact of genotypic variation on disease severity is still lacking. …”
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Opioidergic tuning of social attachment: reciprocal relationship between social deprivation and opioid abuse by Julia A. Galiza Soares, Samantha N. Sutley-Koury, Matthew B. Pomrenze, Matthew B. Pomrenze, Jason M. Tucciarone

“…This review addresses the apparent bidirectional causal relationship between social deprivation and opioid addiction susceptibility, investigating the role of opioid transmission in attachment bond formation and prosocial behavior. …”
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Characterization of the Collagen Extraction Manufacturing Process Using Markov Chains and Artificial Neural Networks by Rosa Trasvina-Osorio, Sergio Alonso-Romero, Juan de Anda-Suarez, Valentin Calzada-Ledesma, Javier Yanez-Mendiola, Luis Fernando Villanueva-Jimenez, Erick Rojas-Mancera

“…Modelling a process requires a priori knowledge of the possible causal relationships between the study variables and the response, especially when the raw material is waste. …”
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Prevalence of Prediabetes, Diabetes, and Its Associated Risk Factors among Males in Saudi Arabia: A Population-Based Survey by Khaled K. Aldossari, Abdulrahman Aldiab, Jamaan M. Al-Zahrani, Sameer H. Al-Ghamdi, Mohammed Abdelrazik, Mohammed Ali Batais, Sundas Javad, Shanila Nooruddin, Hira Abdul Razzak, Ashraf El-Metwally

“…In order to evaluate the causal relationship of these factors, prospective studies are required in future.…”
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Evolution of Magnetohydrodynamic Turbulence in the Expanding Solar Wind: Residual Energy and Intermittency by Chen Shi, Nikos Sioulas, Zesen Huang, Marco Velli, Anna Tenerani, Victor Réville

“…Finally, we find that in our simulations, although the negative residual energy and intermittency grow simultaneously as the turbulence evolves, the causal relation between them seems to be weak, possibly because they are generated on different scales.…”
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Multiepitope Subunit Vaccine Design against COVID-19 Based on the Spike Protein of SARS-CoV-2: An In Silico Analysis by Hamza Arshad Dar, Yasir Waheed, Muzammil Hasan Najmi, Saba Ismail, Helal F. Hetta, Amjad Ali, Khalid Muhammad

“…The global health crisis caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, has resulted in a negative impact on human health and on social and economic activities worldwide. …”
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The Polymorphism rs2725220 Is Associated with Hyperuricemia in the Korean Population by Jae Woong Sull, Seung-Ju Yang, Soriul Kim, Sun Ha Jee

“…Several genome-wide association studies on uric acid levels have implicated the ATP-binding cassette, subfamily G, member 2 (ABCG2) gene as being possibly causal. We investigated an association between the single-nucleotide polymorphism (SNP) rs2725220 in the ABCG2 gene and uric acid levels in the Korean population. …”
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Leveraging LLMs and wearables to provide personalized recommendations for enhancing student well-being and academic performance through a proof of concept by Arfan Ahmed, Sarah Aziz, Alaa Abd-alrazaq, Rawan AlSaad, Javaid Sheikh

“…Future research, particularly with intervention groups and potentially RCT studies, is crucial to establish causal relationships and validate the recommendations’ impact. …”
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Negative perceptions toward older adults and life satisfaction among community-dwelling older citizens in Japan [version 2; peer review: 1 approved, 2 approved with reservations] by Yuho Shimizu, Hiroyuki Suzuki, Tomoki Furuya, Ai Iizuka, Keigo Hinakura, Tomoya Takahashi, Yan Li, Daichi Yamashiro, Yoshifumi Takahashi, Daisuke Cho, Susumu Ogawa, Kenichiro Sato

“…Further exploration is warranted to ascertain whether a causal relationship exists, wherein more negative perceptions of older adults diminish life satisfaction.…”
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Investigating orbital foreign device-associated malignancies: a scoping review by Jeong Hyun Ha, Jagmeet S. Arora, Jamasb J. Sayadi, Nada R. Khattab, Shannon D. Francis, Thomas M. Johnstone, Yeonji Jang, Gordon K. Lee

“…Future studies, including well-designed epidemiologic studies and scientific experiments, are warranted to elucidate the causal relationship.…”
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Detrimental effects of cadmium on male infertility: A review by Nebojša Zečević, Jovana Kocić, Milan Perović, Aleksandar Stojsavljević

“…However, new, in-depth studies are needed to confirm or reject the causal relationship of Cd with male infertility.…”
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Primary Biliary Cirrhosis-Specific Antimitochondrial Antibodies in Neonatal Haemochromatosis by Daniel S. Smyk, Maria G. Mytilinaiou, Tassos Grammatikopoulos, A. S. Knisely, Giorgina Mieli-Vergani, Dimitrios P. Bogdanos, Diego Vergani

“…The association of maternally transferred IgG1 and IgG3 subclass AMA with the appearance of liver damage in an infant with NH may suggest a causal link between antibody and liver damage.…”
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Psychological impacts of "screen time" and "green time" for children and adolescents: A systematic scoping review. by Tassia K Oswald, Alice R Rumbold, Sophie G E Kedzior, Vivienne M Moore

“…However, additional high-quality longitudinal studies and randomised controlled trials are needed to make a compelling case for causal relationships. Different developmental stages appeared to shape which exposures and outcomes were salient. …”
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Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain by Xiaojie Yue, Lei Zhu, Zhigang Zhang

“…Notably, we highlight the <i>App</i> gene, where Lacidofil^® precisely regulated the splicing of two exons causally involved in amyloid β protein-based neurodegenerative diseases. …”
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Russia’s Foreign Trade with the GCC Countries: Dynamics, Characteristics and Opportunities by L. V. Shkvarya

“…The research utilizes various methods, including comparative analysis, statistical analysis, factor analysis, as well as historical, institutional, and causal approaches.…”
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Dynamic System Simulation to Improve the Effectiveness and Efficiency of Supply Chain Performance and Behaviour on Waste Bank Resik Becik by Ratih Setyaningrum, Vida Auralita, Dwi Izzhati, Pramudi Arsiwi, Tita Thalitha

“…The study of SCOR combined with dynamic systems can identify the five dimensions and interaction variables associated with the causal loop design model. SCOR models and dynamic systems provide more effective and efficient value by creating alternative scenarios. …”
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