Gel-Based Autologous Chondrocyte Implantation in a Patient with Noncontained Osteochondral Knee Defect at 9-Year Follow-Up by Ujjval Deliwala, Sumit Jain Sethia

“…Osteochondritis dissecans (OCD) is a disorder of the subchondral bone affecting the adjacent articular cartilage that may lead to cartilage and bone fragment detachment. …”
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Superior Thyroid Cornu Anatomical Variation Causing Globus Pharyngeous and Dysphagia by Jiannis K. Hajiioannou, Vasiliki Florou, Panagiotis Kousoulis

“…Rare case presentation of thyroid cartilage variation causing globus sensation and dysphagia. …”
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Vitamin D Receptor Genetic Variations May Associate with the Risk of Developing Late Fracture-Related Infection in the Chinese Han Population by Xing-qi Zhao, Kun Chen, Hao-yang Wan, Si-ying He, Han-jun Qin, Bin Yu, Nan Jiang

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The Effects of Morus alba and Acacia catechu on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee by Douglas S. Kalman, Susan J. Hewlings

“…Early intervention with UP1306 aimed at reducing bone and cartilage degradation through reported inhibition of catabolic proinflammatory pathways may help to prevent joint cartilage damage. …”
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Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis by Qinghua Fang, Chun Zhou, Kutty Selva Nandakumar

“…Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic, epigenetic, and environmental factors affecting the articular joints contributing to cartilage and bone damage. Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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A Rare Case of Malignant Tumor of the Larynx with Good Prognosis: Laryngeal Chondrosarcoma by Abderrahim Elktaibi, Issam Rharrassi, Nabil Hammoune, Youssef Darouassi, Mohammed Amine Hanine, Haddou Ammar

“…Laryngeal chondrosarcoma is a rare laryngeal tumor that most frequently originates from the cricoid cartilage. The majority of lesions are low grade and the distinction from benign chondromas must be made. …”
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Current Perspectives in Mesenchymal Stem Cell Therapies for Osteoarthritis by Baldur Kristjánsson, Sittisak Honsawek

“…In this review the history and early uses of MSCs in cartilage regeneration are reviewed and different approaches in current trends are explained and evaluated.…”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…Second-look arthroscopy was performed 12 months postoperatively, and the cartilage repair was assessed with the criteria of the International Cartilage Repair Society (ICRS). …”
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Relationship between insertions of the tibialis anterior and peroneus longus and first tarsometatarsal joint degeneration by Kodai Sakamoto, Mutsuaki Edama, Tomoki Hirai, Hirotake Yokota, Ryo Hirabayashi, Chie Sekine, Tomonobu Ishigaki, Makoto Komiya, Taku Toriumi, Ikuo Kageyama

“…The severity of articular cartilage degeneration was assessed in five stages using the International Cartilage Repair Society scale. …”
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Multiscale correlations between joint and tissue-specific biomechanics and anatomy in postmortem ovine stifles by Aritra Chatterjee, Zachary Robert Davis, Timothy Lescun, Deva D. Chan

“…Further, the viscoelastic properties of the tendons and ligaments correlate positively with joint laxity forces; however, no such correlations were observed for the cartilage and menisci. We also found weak inverse correlation between tissue viscoelasticity and T 2 * for MCL; and positive correlations for cartilage and menisci, LCL and PCL respectively. …”
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Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis by Yang Sun, Sanmao Su, Mengjun Li, Ang Deng

“…Hematoxylin–eosin (HE) and safranin O-fast Green (S–O) staining were utilized to access cartilage damage. Ki67 expression in cartilage was detected using immunohistochemistry (IHC). …”
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Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D by Hugo Fabre, Maxime Ducret, Olivier Degoul, Jonathan Rodriguez, Emeline Perrier-Groult, Elisabeth Aubert-Foucher, Marielle Pasdeloup, Céline Auxenfans, Colin McGuckin, Nico Forraz, Frédéric Mallein-Gerin

“…Mesenchymal stem cells (MSCs) represent alternative candidates to chondrocytes for cartilage engineering. However, it remains difficult to identify the ideal source of MSCs for cartilage repair since conditions supporting chondrogenic induction are diverse among published works. …”
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The Interplay of Aging and PANoptosis in Osteoarthritis Pathogenesis: Implications for Novel Therapeutic Strategies by Liu S, Zhang G, Li N, Wang Z, Lu L

“…In OA, dysregulated apoptosis, necroptosis, and pyroptosis, particularly in chondrocytes, exacerbate cartilage damage. Apoptosis, mediated by the JNK pathway, reduces chondrocyte density, while necroptosis and pyroptosis, involving RIPK-1/RIPK-3 and the NLRP3 inflammasome, respectively, amplify inflammation and cartilage destruction. …”
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The associations of physical activity patterns and the triglyceride-glucose index in US adults: a secondary data analysis of NHANES (2007–2018) by JinYe Zhang, YiLin Yang, HaoNan Zheng, BoWen Bai, QianKun Yang, Li Zhang, YuTong Zhao, Jing Luo, Bin Yu

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An Unexpected Complication after Headless Compression Screw Fixation of an Osteochondral Fracture of Patella by Suavi Aydoğmuş, Tahir Mutlu Duymuş, Tolga Keçeci

“…We recommend that the screw heads be embedded to a depth of at least 3 mm below the cartilage surface. Further clinical studies need to examine the variation in cartilage thickness in the fracture fragment.…”
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Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation by Donghyun Kang, Jeeyeon Lee, Geunho Yook, Sehan Jeong, Jungkwon Shin, Mi-Sung Kim, Yi-Jun Kim, Hyeryeon Jung, Jinsung Ahn, Tae Woo Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Won Ho Yang, Yong-ho Lee, Jin Won Cho, Eugene C. Yi, Chanhee Kang, Jin-Hong Kim

“…Abstract UDP-GlcNAc serves as a building block for glycosaminoglycan (GAG) chains in cartilage proteoglycans and simultaneously acts as a substrate for O-GlcNAcylation. …”
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miR-3960 from Mesenchymal Stem Cell-Derived Extracellular Vesicles Inactivates SDC1/Wnt/β-Catenin Axis to Relieve Chondrocyte Injury in Osteoarthritis by Targeting PHLDA2 by Peng Ye, Zhanhu Mi, Daihao Wei, Pengcheng Gao, Mei Ma, Haibo Yang

“…Osteoarthritis (OA) is a serious disease of the articular cartilage characterized by excessive inflammation. …”
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Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells by Yeri Alice Rim, Yoojun Nam, Narae Park, Hyerin Jung, Yeonsue Jang, Jennifer Lee, Ji Hyeon Ju

“…In the context of chondrogenic propensity, CBMC-derived hiPSCs can be a fairly good candidate cell source for cartilage regeneration. The differentiation of hiPSCs into chondrocytes may help develop “cartilage in a dish” in the future. …”
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The Urodele Limb Regeneration Blastema: The Cell Potential by Kenyon S. Tweedell

“…Many specialized cells, bone, cartilage, muscle, and Schwann cells, at the injury site undergo dedifferentiation to a progenitor state and maintain their cell lineage as they redifferentiate in the regenerate. …”
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