Exploring Novel Non-Operative Treatments for Osteoarthritis: An Examination of Innovative Therapies by Piotr Robert Bakuła, Kamila Jałocha, Joanna Zygadło

Subjects: “…cartilage regeneration…”
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Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells by Qi-Ming Huang, You-Qiong Zhuo, Zhong-Xin Duan, Yin-lin Long, Jia-Nan Wang, Zhou-hang Zhang, Shao-Yong Fan, Yong-Ming Huang, Ke-Yu Deng, Hong-Bo Xin

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Development of quality indicators for hand osteoarthritis care – Results from an European consensus study by Daniel H. Bordvik, Yeliz Prior, Rachael Bamford, Francis Berenbaum, Mathilda Björk, Thalita Blanck, Barbara Slatkowsky Christensen, Krysia Dziedzic, John Edwards, Nazemin Gilanliogullari, Carol Graham, Ida K. Haugen, Margreet Kloppenburg, Hellen Laheij, Marco J.P.F. Ritt, Tanja Stamm, Anne Therese Tveter, Nina Østerås, Ingvild Kjeken

“…Osteoarthritis and Cartilage Open…”
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Symptoms indicative of early knee osteoarthritis after ACL reconstruction: descriptive analysis of the SHIELD cohort by Anna Cronström, May Arna Risberg, Martin Englund, Dorthe B. Strauss, Paul Neuman, Carl Johan Tiderius, Eva Ageberg

“…Osteoarthritis and Cartilage Open…”
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Clinical phenotypes and associated factors in knee osteoarthritis in an African black population by Charles Sougué, Malick Diallo, Yannick Laurent Tchenadoyo Bayala, Ismaël Ayouba Tinni, Fulgence Kaboré, Wendlassida Joelle Stéphanie Zabsonré Tiendrebeogo, Patrick Wendpouiré Hamed Dakouré, Dieu-Donné Ouedraogo

“…Osteoarthritis and Cartilage Open…”
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Association of walking cadence to changes in knee pain and physical function: The multicenter osteoarthritis study by Khara A. James, Tuhina Neogi, David T. Felson, Patrick Corrigan, Cara L. Lewis, Irene S. Davis, Kathryn L. Bacon, James C. Torner, Cora E. Lewis, Michael C. Nevitt, Joshua J. Stefanik

“…Osteoarthritis and Cartilage Open…”
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Do cognitive bias and heuristics influence improvement in knee pain in patients with knee osteoarthritis treated with open label placebo? The CHIPS study - An exploratory study usi... by Tommy Kok Annfeldt, Elisabeth Ginnerup-Nielsen, Eva Elisabeth Wæhrens, Lene Vase, Lars Erik Kristensen, Tanja Schjødt Jørgensen

“…Osteoarthritis and Cartilage Open…”
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Effect of glucagon-like peptide-1 receptor agonists in osteoarthritis: A systematic review of pre-clinical and human studies by Jacinta Cheng, Tia Solomon, Mahnuma Estee, Flavia M. Cicuttini, Yuan Z. Lim

“…Osteoarthritis and Cartilage Open…”
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Study on the protective effect of naringin-regulated lncRNA GAS5 against mitochondrial apoptosis in osteoarthritic chondrocytes by LIN Qin, ZHU Yingkai, LIN Yanming, LAN Shujie, CHEN Changxing, FU Changlong

“…Magnetic resonance imaging and ultrasound were used to identify the success of modeling; histopathological changes in rat articular cartilage were assessed using toluidine blue and saffron O staining; changes in the levels of lncRNA GAS5 in rat cartilage tissues after naringin intervention were detected by Real-time PCR; Western blot detected Caspase-3, Bax, MMP-13 and Cyt-C in rat cartilage tissues. …”
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Adipose-Derived Stem Cells Cocultured with Chondrocytes Promote the Proliferation of Chondrocytes by Jie Shi, Jiulong Liang, Bingyu Guo, Yu Zhang, Qiang Hui, Peng Chang, Kai Tao

“…Articular cartilage injury and defect caused by trauma and chronic osteoarthritis vascularity are very common, while the repair of injured cartilage remains a great challenge due to its limited healing capacity. …”
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Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants by Margo Tuerlings, Evelyn Houtman, Elisa J.H. Muusers, Janneke Simon, Maurice W. de Haan, Ilja Boone, Yolande F.M. Ramos, Rachid Mahdad, Ingrid Meulenbelt

“…Abstract Objective To explore IL11 co-expression profiles in our previously reported RNA-sequencing dataset of OA articular cartilage, in interaction with IL6, and to investigate the effects of hrIL11 administration as potential therapeutic strategy for OA articular cartilage using our biomimetic aged human osteochondral explant model of OA. …”
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Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study by Joonas Sirola, Anna-Kaisa Koistinen, Kari Salovaara, Toni Rikkonen, Marjo Tuppurainen, Jukka S. Jurvelin, Risto Honkanen, Esko Alhava, Heikki Kröger

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DAMPs Synergize with Cytokines or Fibronectin Fragment on Inducing Chondrolysis but Lose Effect When Acting Alone by Lei Ding, Joseph A. Buckwalter, James A. Martin

“…Injured cartilage-conditioned culturing medium containing a mixture of DAMPs was employed as a control. …”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA.…”
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Herbal remedies as a potential alternative therapy for arthritis by Disha Trivedi, Riya Jayapal Roja, Eva Künnemann

“…These are marked by specific molecular patterns and immunological pathways that lead to chondrolysis and destruction of cartilage. Natural plant substances can influence these pathways and help to break out of the vicious cycle and to find a way for stopping the disease or even to regenerate and heal injured cartilage. …”
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Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy by Ronaldo J. F. C. do Amaral, Henrique V. Almeida, Daniel J. Kelly, Fergal J. O’Brien, Cathal J. Kearney

“…The ideal cell type to be used for cartilage therapy should possess a proven chondrogenic capacity, not cause donor-site morbidity, and should be readily expandable in culture without losing their phenotype. …”
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Acute Traumatic Injury of the Larynx by K. O. Kragha

“…Two case histories are presented: (1) case history A: a 53-year-old male, after motor vehicle accident, fractured the mid anterior thyroid cartilage and both aspects of the cricoid cartilage; however, this patient was asymptomatic from the above fractures; and (2) case history B: a 41-year-old male who sustained trauma to the chest, neck, and left arm after being struck by a large lead pipe which fractured the left aspect of the cricoid cartilage was symptomatic. …”
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Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects by Henning Madry, Liang Gao, Hermann Eichler, Patrick Orth, Magali Cucchiarini

“…A bone marrow clot forms within the cartilage defect either as a result of marrow stimulation or during the course of the spontaneous repair of osteochondral defects. …”
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Synergistic Effects of FGF-18 and TGF-β3 on the Chondrogenesis of Human Adipose-Derived Mesenchymal Stem Cells in the Pellet Culture by Liangjie Huang, Lingxian Yi, Chunli Zhang, Ying He, Liangliang Zhou, Yan Liu, Long Qian, Shuxun Hou, Tujun Weng

“…Cell-based therapy serves as an effective way for cartilage repair. Compared with a limited source of autologous chondrocytes, adipose-derived stem cells (ADSCs) are proposed as an attractive cell source for cartilage regeneration. …”
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Corrigendum to “New Issues in the Management of Osteoporosis” by Joonas Sirola, Manuel Diaz Curiel, Risto Honkanen, Jun Iwamoto

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