Mesenchymal Stem Cells in Renal Fibrosis: The Flame of Cytotherapy by Quan Zhuang, Ruoyu Ma, Yanshuang Yin, Tianhao Lan, Meng Yu, Yingzi Ming

“…MSCs are pluripotent adult stem cells that can differentiate into various types of tissue lineages, such as the cartilage (chondrocytes), bone (osteoblasts), fat (adipocytes), and muscle (myocytes). …”
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The Role of Anatomical Imaging and Intraoperative Neuromonitoring (IONM) for Successful Prediction of a Nonrecurrent Laryngeal Nerve by Hiroki Kuwazoe, Keisuke Enomoto, Daichi Murakami, Naoko Kumashiro, Saori Takeda, Muneki Hotomi

“…After separating the connective tissue on the thyroid capsule from the right side of the trachea to the inferior pole laterally, the NRLN running across the level of the inferior margin of the cricoid cartilage was identified by using IONM 0.5 mA stimulation. …”
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Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research by Satoru Morikawa, Takehito Ouchi, Shinsuke Shibata, Takumi Fujimura, Hiromasa Kawana, Hideyuki Okano, Taneaki Nakagawa

“…In contrast, mesenchymal stem cells (MSCs) are easily accessible in adults, have similar potential for self-renewal, and can differentiate into skeletal tissues, including bones and cartilage. Therefore, MSCs may represent good sources of stem cells for clinical use. …”
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Robotic-Assisted Total Knee Arthroplasty for Distal Femur Fracture with Lateral Knee Osteoarthritis by Takao Kaneko, Tadashi Igarashi, Shu Yoshizawa, Kazutaka Takada, Hiroyasu Ikegami, Yoshiro Musha

“…RA TKA could determine osteotomy and implant placement by predicting the postoperative patient’s soft tissue balance for no medial loosening and lateral contracture. The arthritic cartilage and bone were then methodically removed using the handheld sculptor. …”
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Cryopreserved Umbilical Cord Mesenchymal Stem Cells Show Comparable Effects to Un-Cryopreserved Cells in Treating Osteoarthritis by Bo Yan, Huixin Chen, Li Yan, Qiang Yuan, Le Guo

“…In vivo, UC-MSCs and C-MSCs exhibited similar cartilage-repairing effects by attenuating pain and alleviating pathological changes in OA rat joints. …”
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Intervertebral disc regeneration – Is it possible? by Dragos Schiopu, Arnaud Devriendt, Clara Van Vyve, Tamas S. Illes

“…Objective: The aim of this study was to evaluate disc metabolism after decreasing the axial load through surgery by assessing the glycosaminoglycan content through a non-invasive method—delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC). Methods: Sixteen patients with mono-segmental disc degeneration (L4-L5 or L5-S1) who underwent posterior lumbar spine fixation with intervertebral distraction of 2 consecutive vertebrae using monoaxial transpedicular screws and lyophilized allograft to achieve segmental fusion, and who had a follow-up period of at least 2 years, were included in this study. …”
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Candidate antirheumatic genotherapeutic plasmid constructions have low immunogenicity by T. S. Nepomnyashchikh, T. V. Tregubchak, S. N. Yakubitskiy, O. S. Taranov, R. A. Maksyutov, S. N. Shchelkunov

“…In the course of RA the degenerative changes occur in cartilage surfaces of affected joints and also in subchondral bone tissue, joints get deformed and lose their mobility. …”
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Detection and Severity Assessment of Temporomandibular Joint Osteoarthritic Changes in Patients with Temporomandibular Disorders Using CBCT by Kharman Khidhr Rahman, Shahen Ali Ahmed, Sarkawt Hamad Ali, Khoshee Salh Hamed

“…It involves the gradual breakdown of bone, cartilage, and surrounding soft tissues around the joints. …”
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Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference by Jingjing Kong, Yingying Yang, Shuzhen Sun, Jianli Xie, Xuefen Lin, Ping Ji

“…Some investigations suggested that the increasing expression of IL-1β secreted by synovial lining cells plays an important role in synovial inflammation and cartilage destruction in TMJ. In our previous research, the results demonstrated that TLR4 is involved in the expression of IL-1β in SFs from TMJ with lipopolysaccharide stimulation. …”
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Biochemical Characterization of Early Osteoarthritis in the Ankle by Hagen Schmal, Gian M. Salzmann, Elia R. Langenmair, Ralf Henkelmann, Norbert P. Südkamp, Philipp Niemeyer

“…Results. ICRS grading of cartilage damage, previous operations, and duration of complains were strong indicators for OA progress and showed correlations to age, clinical scores, validated KLS, and AOSS (P<0.04). …”
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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat by François Brial, Aurélie Le Lay, Claude Rouch, Edouard Henrion, Mathieu Bourgey, Guillaume Bourque, Mark Lathrop, Christophe Magnan, Dominique Gauguier

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3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications by Shanshan Han, Kexin Nie, Jingchao Li, Qingqing Sun, Xiaofeng Wang, Xiaomeng Li, Qian Li

“…The applications of 3D ENF-S in cartilage, bone, tendon, ligament, skeletal muscle, nerve, and cardiac tissue regeneration are then presented with a discussion of current challenges and future directions. …”
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Long-term outcomes after fixation of pure chondral fragment from the femoral trochlea in adolescents –three case reports- by Shuto Yamashita, Ryohei Uchida, Tomohiko Matsuo, Norimasa Nakamura, Shuji Horibe, Yukiyoshi Toritsuka

“…Radiographs showed no osteoarthritic changes and MRI showed good integration with the surrounding native cartilage and smooth surface in all cases. In all cases, Lysholm score and IKDC score were over 95, and most of KOOS were over 90. …”
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Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment by Li G, He F, Feng J, Xu G, Wu C, Qiao Y, Liu Y, Chen H, Du P, Wang J

“…In an enzymolysis model of rat OA, PAs/PF127 nanospheres significantly reduce joint space swelling in the early stages of cartilage destruction and accelerate the formation of subchondral bone and cartilaginous surface.Implication: This study offers valuable insights into the preparation of novel PA nanospheres for effective repair of OA.Keywords: procyanidin, self-assembling nanospheres, injectable, osteoarthritis treatment…”
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Histological and Immunohistochemical Evaluation of Autologous Cultured Bone Marrow Mesenchymal Stem Cells and Bone Marrow Mononucleated Cells in Collagenase-Induced Tendinitis of E... by Antonio Crovace, Luca Lacitignola, Giacomo Rossi, Edda Francioso

“…In cBMSC- and BMMNCS-treated tendons, a high expression of cartilage oligomeric matrix protein (COMP) and type I collagen, but low levels of type III collagen were revealed by immunohistochemistry, with a normal longitudinally oriented fiber pattern. …”
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Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry by Rachel J. Knobel, Naoaki Ito, Elanna K. Arhos, Jacob J. Capin, Thomas S. Buchanan, Lynn Snyder-Mackler

“…Slower walking speeds have been associated with biomarkers suggesting cartilage breakdown. The relationship between walking speed and gait symmetry after ACLR is unknown…”
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Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century by J.-F. Stoltz, N. de Isla, Y. P. Li, D. Bensoussan, L. Zhang, C. Huselstein, Y. Chen, V. Decot, J. Magdalou, N. Li, L. Reppel, Y. He

“…Different clinical applications are under study (cardiac insufficiency, atherosclerosis, stroke, bone and cartilage deterioration, diabetes, urology, liver, ophthalmology, and organ’s reconstruction). …”
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Production of Adult Human Synovial Fluid-Derived Mesenchymal Stem Cells in Stirred-Suspension Culture by Kristen D. Jorgenson, David A. Hart, Roman Krawetz, Arindom Sen

“…The chondrogenic potential of synovial fluid-derived mesenchymal stem cells (SF-MSCs) supports their use in cartilage regeneration strategies. However, their paucity in synovial fluid necessitates their proliferation in culture to generate clinically relevant quantities. …”
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Quadriceps and Hamstrings Activation Peaks Earlier as Athletes Repeatedly Hop, but There are Differences Depending on ACL Reconstruction Technique. by Einar Einarsson, Olivia Barbosa, Magnus Kjartan Gislason, Kristin Briem, Argyro Kotsifaki, Rodney Whiteley

“…# Background After Anterior Cruciate Ligament Reconstruction (ACLR) athletes face the challenge of regaining their previous competitive level while avoiding re-injury and early knee joint cartilage degeneration. Quadriceps and hamstrings strength reductions and neuromuscular alterations potentially related to risk of re-injury are present after ACLR and relate to deficits in muscle activation…”
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IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes by Yusuke Watanabe, Aki Namba, Yukiko Aida, Kazuhiro Honda, Hideki Tanaka, Naoto Suzuki, Hideo Matsumura, Masao Maeno

“…Elevated interleukin (IL)-1 concentrations in synovial fluid have been implicated in joint bone and cartilage destruction. Previously, we showed that IL-1β stimulated the expression of prostaglandin (PG) receptor EP4 via increased PGE2 production. …”
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