Cytokine Reduction in the Treatment of Joint Conditions by J. D. Sipe, J. Martel-Pelletier, I. G. Otterness, J.-P. Pelletier

“…The destruction of joints caused by rheumatoid arthritis and osteoarthritis is characterized by an imbalance of enzyme catalysed cartilage breakdown and regeneration. A complex cytokine network perpetuates joint conditions by direct regulation of metalloproteases, by indirect recruitment of cells that secrete degradative enzymes, and by inhibition of reparative processes. …”
Get full text

Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa by Nelson Bergonse Neto, Lianna Ferrari Jorge, Julio C. Francisco, Bruna Olandoski Erbano, Barbara Evelin Gonçalves Barboza, Larissa Luvison Gomes da Silva, Marcia Olandoski, Katherine Athayde Teixeira de Carvalho, Luiz Felipe Pinho Moreira, Jose Rocha Faria Neto, Eltyeb Abdelwahid, Luiz Cesar Guarita-Souza

“…Histological analysis revealed immature cartilage, pseudostratified ciliated epithelium, and connective tissue in 54.5% (p=0.018) of the SIS group, while no cartilaginous regeneration was observed in the control group. …”
Get full text

Mesenchymal Stem Cells and Cardiovascular Disease: A Bench to Bedside Roadmap by Manuel Mazo, Miriam Araña, Beatriz Pelacho, Felipe Prosper

“…Mesenchymal progenitors, owing to their availability, ease of manipulation, and therapeutic potential, have become one of the most attractive options for the treatment of a wide range of diseases, from cartilage defects to cardiac disorders. Moreover, their immunomodulatory capacity has opened up their allogenic use, consequently broadening the possibilities for their application. …”
Get full text

Fat Graft Myringoplasty versus Chemical Cauterization in Small Tympanic Membrane Perforation:A Comparative Study by Vertika Tewari, Mohamed Tabrez Bahauddin Gafoor, Harendra Kumar Gautam, Azme Zehra, Priyali Singh

“…A variety of autografts have been used for closure of tympanic membrane perforation such as perichondrium. temporalis fascia, cartilage fat, platelet rich plasma, and chemical cauterization. …”
Get full text

Matrix Gla Protein Binds to Fibronectin and Enhances Cell Attachment and Spreading on Fibronectin by Satoru Ken Nishimoto, Miyako Nishimoto

“…MGP is a calcification inhibitor of arteries and cartilage. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. …”
Get full text

ATP-Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells by Wen Du, Daimo Guo, Wei Du

“…Mesenchymal stem cells (MSCs) present in multiple tissues can self-renew and differentiate into multiple lineages including the bone, cartilage, muscle, cardiac tissue, and connective tissue. …”
Get full text

Insight in Hypoxia-Mimetic Agents as Potential Tools for Mesenchymal Stem Cell Priming in Regenerative Medicine by Agata Nowak-Stępniowska, Paulina Natalia Osuchowska, Henryk Fiedorowicz, Elżbieta Anna Trafny

“…These agents are not studied so wildly as hypoxia but, considering the low cost and ease of use, are believed to find application as pretreatment of many diseases such as ischemic heart disease and myocardial fibrosis and promote cardiac and cartilage regeneration. The knowledge of MSC priming is critical in evaluating safety procedures and use in clinics. …”
Get full text

Correction of Anophthalmic Enophthalmos with a Three-Staged Procedure: Two Case Reports by Tomohiro Minagawa, Ryuta Shioya, Takeshi Yamao, Chigusa Sato, Taku Maeda

“…Accordingly, a three-staged procedure was performed on the second patient, including autologous augmentation of the eye socket, correction of lower eyelid retraction with a cartilage graft, and a frontalis sling procedure to correct upper eyelid ptosis.…”
Get full text

Poly(vinyl alcohol) Hydrogels: The Old and New Functional Materials by Menghan Wang, Jianzhong Bai, Kan Shao, Wenwei Tang, Xueling Zhao, Donghai Lin, Shan Huang, Cheng Chen, Zheng Ding, Jiayi Ye

“…PVA-based hydrogels have been widely investigated in drug carriers, articular cartilage, wound dressings, tissue engineering, and other intelligent materials, such as self-healing and shape-memory materials, supercapacitors, sensors, and other fields. …”
Get full text

MLL4 regulates postnatal palate growth and midpalatal suture development by Jung-Mi Lee, Hunmin Jung, Bruno de Paula Machado Pasqua, Yungki Park, Qinghuang Tang, Shin Jeon, Shin Jeon, Soo-Kyung Lee, Jae W. Lee, Hyuk-Jae Edward Kwon

“…Genome-wide mRNA expression analysis of the midpalatal suture tissue revealed that MLL4 is essential for the timely expression of major cartilage development genes, such as Col2a1 and Acan, at birth. …”
Get full text

Gold Finger: Metal Jewellery as a Disease Modifying Antirheumatic Therapy! by T. Hlaing, S. Ramteke, K. Binymin

“…The disease can progress rapidly causing joint swelling and damaging cartilage and bone around the joints resulting in severe deformities. …”
Get full text

Narrative Review and Guide: State of the Art and Emerging Opportunities of Bioprinting in Tissue Regeneration and Medical Instrumentation by Jaroslava Halper

“…Bioprinting is suitable for printing tissues using living or viable components, such as collagen scaffolding, cartilage components, and cells, and also for printing parts of structures, such as teeth, using artificial man-made materials that will become embedded in vivo. …”
Get full text

Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis by Yinzi Xin, Wei Wang, Enyu Mao, Hefeng Yang, Song Li

“…The mechanism of temporomandibular joint osteoarthritis (TMJOA), which leads to the final erosion of cartilage and subchondral bone, has been widely demonstrated, but still not clearly elucidated. …”
Get full text

A Quantitative Study on the Trachea of the Red Sokoto (Maradi) Goat (Capra hircus) by O. Byanet, J. A. Bosha, B. O. Onoja

“…The results showed that tracheas were extended from the cricoid cartilage of larynx to the hilus of the lungs, where they were divided into the right and left bronchi. …”
Get full text

The Relationship between Osteoporosis and Osteoarthritis of the Knee: A Report of 2 Cases with Suspected Osteonecrosis by Akira Horikawa, Naohisa Miyakoshi, Yoichi Shimada, Hiroyuki Kodama

“…Pathological examination of the resected femoral condyle and proximal tibia showed almost intact joint cartilage, healing of the collapsed subchondral bone, and significant trabecular bone loss. …”
Get full text

Laryngeal Fracture after Blunt Cervical Trauma in Motorcycle Accident and Its Management by Nuno Ribeiro-Costa, Pedro Carneiro Sousa, Diogo Abreu Pereira, Paula Azevedo, Delfim Duarte

“…CT-scan demonstrated displaced fracture of the cricoid and thyroid cartilage. The patient was submitted to tracheostomy and the fracture was surgically repaired. …”
Get full text

Autoantibodies as Diagnostic Markers and Mediator of Joint Inflammation in Arthritis by Qinghua Fang, Jiaxin Ou, Kutty Selva Nandakumar

“…Interplay between several molecules (cytokines, chemokines, proteases, and inflammatory mediators) culminates in causing damage to the articular cartilage and bones. In addition, autoantibodies are proven to be useful disease markers for RA, and different diagnostic tools are being developed for early diagnosis of the clinical disease. …”
Get full text

Calcified Leiomyoma of the Distal Forearm in a Child: A Case Report and Review of Literature by Nadeeke Nidhan Perera, Sunil Ranjith Wijayasinghe, Karuna Dissanayake, Jerard Fernando, Ethige Tharushi De Silva

“…MRI also confirmed a well-defined soft tissue lesion with areas of calcifications. A diagnosis of a cartilage-forming lesion or a peripheral nerve sheath tumour was suggested. …”
Get full text

Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering by Yuting Li, Hao Meng, Yuan Liu, Bruce P. Lee

“…The ability for fibrin to cure in situ has been exploited to develop injectable scaffolds for the repair of damaged cardiac and cartilage tissues. Additionally, fibrin gel has been utilized as a cell carrier to protect cells from the forces during the application and cell delivery processes while enhancing the cell viability and tissue regeneration. …”
Get full text

Hamster and Murine Models of Severe Destructive Lyme Arthritis by Erik Munson, Dean T. Nardelli, Brian K. Du Chateau, Steven M. Callister, Ronald F. Schell

“…This arthritis involves focal bone erosion and destruction of articular cartilage. Hamsters and mice are animal models that have been utilized to study articular manifestations of Lyme borreliosis. …”
Get full text