Arteriovenous Malformation in the Auricle in a 59-Year-Old Woman by Junhui Jeong

“…AVM in the ear should be managed carefully because the skin is thin in the ear, the cartilage could be involved, and progressive growth or inappropriate management could cause bleeding, infection, and cosmetic problems such as deformity. …”
Get full text

Hydrogen Supplementation of Preservation Solution Improves Viability of Osteochondral Grafts by Takuya Yamada, Kentaro Uchida, Kenji Onuma, Jun Kuzuno, Masanobu Ujihira, Gen Inoue, Bunpei Sato, Ryosuke Kurokawa, Rina Sakai, Masashi Takaso

“…Our findings demonstrate that OCTs preserved in DMEM supplemented with hydrogen are a promising material for the repair of large cartilage defects in the clinical setting.…”
Get full text

Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells by Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang

“…Although mesenchymal stem cells (MSCs) derived extracellular vesicles (EVs) are promising for promoting cartilage regeneration, their clinical application is limited by inconsistent therapeutic effects and insufficient targeting capabilities. …”
Get full text

Single-cell transcriptomics reveals novel chondrocyte and osteoblast subtypes and their role in knee osteoarthritis pathogenesis by Yuan Liu, Wacili Da, Ming-Jie Xu, Chao-Xin Xiao, Tao Deng, Sheng-Liang Zhou, Xiao-Ting Chen, Yao-Jia Zhou, Li Tang, Yong Nie, Yi Zeng, Hui-Qi Xie, Bin Shen

“…The pathogenesis of KOA is complex for being a multifactorial disease affecting the entire joint, with remodeling of subchondral bone playing a key role in the degeneration of the overlying cartilage. Therefore, this study constructed a bipedal postmenopausal KOA mouse model to better understand how the interplay between subchondral bone remodeling and cartilage degeneration contributes to KOA development. …”
Get full text

Xenoimplantation of an Extracellular-Matrix-Derived, Biphasic, Cell-Scaffold Construct for Repairing a Large Femoral-Head High-Load-Bearing Osteochondral Defect in a Canine Model by Yang Qiang, Zhao Yanhong, Peng Jiang, Lu Shibi, Guo Quanyi, Ma Xinlong, Xia Qun, Xu Baoshan, Zhao Bin, Wang Aiyuan, Zhang Li, Xu Wengjing, Zeng Chao

“…The scaffolds were fabricated using cartilage and bone ECM as a cartilage and bone layer, respectively. …”
Get full text

The potential of urinary miR-200c-3p as a biomarker of fluorosis in rats by Ailin Li, Jian Wang, Xinyue Meng, Xu Ma, Ying Liu, Hanying Li, Zhe Mo, Rui Zhang, Lei Wu, Shirui Yan, Paula Fiorella Chacon Campoverde, Gazala Zafar, Yongzheng Ma, Wenjun Que, Zhe Li, Tuo Wang, Korto Fatti Tarnue, Junrui Pei

“…This study aimed to evaluate the time-dose-effect relationship of miR-200c-3p in plasma, urine and cartilage of rats with drinking water fluorosis, and to explore its potential as a biomarker. …”
Get full text

Metaplastic Carcinoma of the Breast with Squamous Differentiation: A Case Report from the University Teaching Hospital of Kigali (CHUK), Rwanda by Delphine Uwamariya, Carine Nyampinga, Anne Yvette Nsenguwera, Belson Rugwizangoga

“…Morphologically, it is characterized by the differentiation of neoplastic epithelium into epithelial or mesenchymal-looking elements like squamous cells, spindle cells, cartilage, or bone and has poor prognosis with its triple negative status.…”
Get full text

A Case Report and Literature Review of Bilateral Cervical Chondrocutaneous Branchial Remnants by Yuehua He, Huiling Zhu, Hang Ji, Weining Huang, Zhongrong Liu

“…The pathological report following surgical resection revealed that the lesion was located in the dermis and consisted primarily of hyaline cartilage tissue enclosed by a fibrous capsule, with few local vascular proliferations. …”
Get full text

Shoulder Dislocation in Children. A Case Presentation by Eduardo García Pérez, Yovanny Ferrer Lozano, Yanett Morejón Trofimova

“…In pediatric age, epiphysis fractures are more common that the sprains  or dislocations due to the presence of bone tissue that can undergo a greater elastic deformation, a thick periosteum, stabilizer and ligaments with greater resistance to breakage than growth cartilage. We report the case of a white skinned male of 2 years old that was treated in our department because of a right scapulohumeral dislocation. …”
Get full text

A Case of First Branchial Cleft Fistula Presenting with an External Opening on the Root of the Helical Crus by Sung Il Cho

“…Complete excision of the tract, including the cuff of surrounding cartilage, was performed. Histopathology revealed a fistular tract lined with squamous epithelium. …”
Get full text

Lateral Decubitus 360° Capsular Release for Treatment of Recalcitrant End-Stage Adhesive Capsulitis by Juan Bernardo Villarreal-Espinosa MD, Rodrigo Saad Berreta BA, Richard Danilkowicz MD, Udit Dave BS, Melissa Carpenter BS, Jorge Chahla MD, PhD, Nikhil N. Verma MD

“…Additionally, risk of cerebral hypoperfusion and iatrogenic injury to the cartilage surfaces while instrumenting the joint is diminished. …”
Get full text

Characterization of a chemically induced osteoarthritis model in zebrafish by Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie

“…Abstract Osteoarthritis (OA) is characterized by the progressive degeneration of the synovial joint, leading to irreversible damage to articular cartilage and subchondral bone. While animal models have advanced our understanding of OA, numerous unresolved issues still remain. …”
Get full text

Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold... by Takuya Yamada, Kentaro Uchida, Kenji Onuma, Gen Inoue, Jun Aikawa, Shotaro Takano, Hiroyuki Sekiguchi, Hisako Fujimaki, Masayuki Miyagi, Masashi Takaso

“…Osteochondral allografting is a promising option for the treatment of large cartilage defects. However, because the cell viability of osteochondral tissues (OCTs) gradually reduces during storage at 4°C, methods for maintaining the cell viability of fresh OCTs are needed to improve transplantation outcomes. …”
Get full text

New Insights on Properties and Spatial Distributions of Skeletal Stem Cells by Jun-qi Liu, Qi-wen Li, Zhen Tan

“…Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. …”
Get full text

Laryngeal Chondrosarcoma as a Rare Cause of Subglottic Stenosis by Kerem Kökoğlu, Özlem Canöz, Serap Doğan, Emrah Gülmez, İmdat Yüce, Sedat Çağlı

“…It is developed from cricoid cartilage largely. Patients have laryngeal CS complaint of respiratuvar distress, dysphonia, and dysphagia generally. …”
Get full text

Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases by Vani Krishnamurthy, Sheela Devi C. Shivalingiah, Sunila Ravishankar, Gubbanna V. Manjunath

“…The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.…”
Get full text

Extraosseous Intradural Chondrosarcoma of the Cervical Spine: A Case Report with Brief Review of Literature by Elizabeth Presutto, Sejal Patel, Joseph Fullmer, Sajeev Ezhapilli

“…Mesenchymal chondrosarcoma (MCS) is a malignant cancer of the cartilage that accounts for less than 1% of all chondrosarcomas and typically occurs within the bone. …”
Get full text

Ostéochondronécroses articulaires by Silvia Boccone, Rosa Boano, Enzo Fulcheri, Emma Rabino Massa

“…Osteochondronecrosis is a generic term which defines lesions of vascular origin in the joints, characterized by localized cartilage detachment and associated with or subsequent to localized subchondral bone necrosis. …”
Get full text

IMPACT OF ORTHODONTIC DYSFUNCTIONS ON THE DEVELOPMENT OF JOINT OSTEOARTHRITIS by Oleg Solomon, Norina Consuela Forna, Doriana Agop Forna, Irina Adriana Beuran, Diana Cornea, Kamel Earar

“…Osteoarthritis is a chronic degenerative condition that affects the articular cartilage, leading to pain, dysfunction and decreased quality of life. …”
Get full text

Diagnostic performance of point-of-care ultrasonography (POC-US) in haemophilia joint health: a comparative study with MRI by Duseja Yash, Kashyap Arnav, Dutta Anupam, Borpatragohain Dhrubajyoti, Dhal Bhabani, Borboruah Luish

“…Aims: The study aimed to assess the diagnostic performance of point-of-care ultrasonography (POC-US) compared to magnetic resonance imaging (MRI) in detecting synovial hypertrophy, cartilage abnormality, and bony abnormality among people with haemophilia (PWH) treated at Assam Medical College Hospital.…”
Get full text