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Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway
Published 2025-01-01“…Xiao Luo,1,2,* Ling Chen,2,* Jingsong Xu,1 Juxiang Li1 1Department of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, People’s Republic of China; 2Department of Cardiovascular Medicine, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang No. 1 People’s Hospital, Jiujiang, Jiangxi, 332000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Juxiang Li, Department of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1, Minde Road, Donghu District, Nanchang, Jiangxi, 330000, People’s Republic of China, Tel +86 15707923841, Email ndefy87008@ncu.edu.cnObjective: To explore the effect of Naoxintong (NXT) on warfarin anticoagulation therapy and its potential mechanism.Methods: TCSMP, SwissTargetprediction, SuperPred, SEA, and Batmanic-TCM were used to search for active ingredients and targets of NXT and warfarin; the DisGENT database was used to find disease targets of coagulation disorders. …”
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