The role of Beringia in human adaptation to Arctic conditions based on results of genomic studies of modern and ancient populations by B. A. Malyarchuk

“…The adaptation of Amerindian ancestors to high latitudes and cold climates is supported by genomic data showing that adaptive genetic variants in Native Americans are associated with various metabolic pathways: melanin production processes in the skin, hair and eyes, the functioning of the cardiovascular system, energy metabolism and immune response characteristics. …”
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Risk factor assessment of prediabetes and diabetes based on epidemic characteristics in new urban areas: a retrospective and a machine learning study by Li Xu, Xiangcheng Sun, Ning Wang, Yiyi Wang, Yan Li, Chuan Zhang

“…Risk factor assessment in different states suggested that early risk factors for diabetes pathogenesis were associated with aging, metabolic disorders and obesity, and the consequent risk factors for disease progression were liver, cardiovascular and kidney dysfunction. Our machine learning model was used for disease risk estimation. …”
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Central Aortic Pressure and Arterial Stiffness in Parkinson’s Disease: A Comparative Study by Mehmet Balal, Meltem Demirkiran, Saime Paydas

“…Background. Cardiovascular autonomic dysfunction, which leads to hemodynamic disorders, is commonly observed in patients with Parkinson’s disease (PD). …”
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Effects of brain renin- angiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension by L. O. Klimov, M. A. Ryazanova, L. A. Fedoseeva, A. L. Markel

“…The renin-angiotensin system (RAS) is one of the main systems regulating arterial pressure and water-salt homeostasis of the body and is involved in the pathogenesis of cardiovascular diseases. Angiotensin peptides – products of enzymatic hydrolysis of angiotensinogen – can be synthesized not only in the blood stream, but also in tissues, including various regions  of the brain. …”
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Insulin versus Lipid Emulsion in a Rabbit Model of Severe Propranolol Toxicity: A Pilot Study by Martyn Harvey, Grant Cave, Daniel Lahner, Jan Desmet, Gaynor Prince, Gary Hopgood

“…Beta-blocker overdose may result in intractable cardiovascular collapse despite conventional antidotal treatments. …”
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Trans fatty acids and saturated fatty acids in margarines and spreads in Kazakhstan: Study period 2015–2021 by Kainaubek Toshtay, Ali Auyezov, Seitkhan Azat, Rosa Busquets

“…The strong cause effect between TFA and cardiovascular diseases urges Kazakhstan and other countries to reduce TFA in commercial products. …”
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Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise by Giuseppe Lippi, Gian Luca Salvagno, Elisa Danese, Cantor Tarperi, Gian Cesare Guidi, Federico Schena

“…These results may have implications for definition of reference ranges and antidoping testing, and may also contribute to explaining the relationship between endurance exercise and mortality, since previous studies reported that RDW and MPV may be significantly associated with cardiovascular disease.…”
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Photofunctional Co-Cr Alloy Generating Reactive Oxygen Species for Photodynamic Applications by Kang-Kyun Wang, Bong-Jin Kim, Mi Hee Lee, Byeong-Ju Kwon, Dong Hoon Choi, Jong-Chul Park, Yong-Rok Kim

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Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases by Muneo Yamaguchi, Shintaro Nakao, Mitsuru Arima, Iori Wada, Yoshihiro Kaizu, Feng Hao, Shigeo Yoshida, Koh-hei Sonoda

“…Its involvement in various diseases, particularly cancer and cardiovascular disease, has been elucidated, and ROCK inhibitors have already been applied clinically for cerebral vasospasm and glaucoma. …”
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To what extent is socioeconomic status associated with not taking up and dropout from cardiac rehabilitation: a population-based follow-up study by Thomas Maribo, Christina M Stapelfeldt, Marie Louise Svendsen, Birgitte Bitsch Gadager, Maiken Bay Ravn, Sanne Moeller Palner

“…The objective of this study was to examine whether indicators of SES are associated with not taking up and dropout from CR.Design A population-based, follow-up study.Setting Hospitals and primary healthcare centres in the Central Denmark Region.Participant Patients diagnosed with ischaemic heart disease (IHD) in the hospital and referred for rehabilitation in the primary healthcare setting from 1 September 2017 to 31 August 2018 (n=2018).Variables Four SES indicators (education, disposable family income, occupation and cohabitant status) were selected because of their established association with cardiovascular health and CR utilisation. Patients were followed up regarding no uptake of or dropout from CR in the primary healthcare setting.Statistical methods The associations between the four SES indicators and either no uptake or dropout from CR were analysed using logistic regression with adjustment for age, sex, nationality and comorbidity.Results Overall, 25% (n=507) of the referred patients did not take up CR and 24% (n=377) of the participators dropped out the CR. …”
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Deep learning for the classification of atrial fibrillation using wavelet transform-based visual images by Ling-Chun Sun, Chia-Chiang Lee, Hung-Yen Ke, Chih-Yuan Wei, Ke-Feng Lin, Shih-Sung Lin, Hsin Hsiu, Ping-Nan Chen

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Tailoring the Ablative Strategy for Atrial Fibrillation: A State-of-the-Art Review by Zefferino Palamà, Martina Nesti, Antonio Gianluca Robles, Antonio Scarà, Silvio Romano, Elena Cavarretta, Maria Penco, Pietro Delise, Mariano Rillo, Leonardo Calò, Luigi Sciarra

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Characteristics and Demographics of Patients Requiring Emergent Air Medical by Anna Van Tuyl, Mark Quilon, Trevor Dudley, Olivia Grant, Neha Rao, Paul Barbara, David S. Kugler, Kaitlin C. McLoone-Cepin, Josh Greenstein, Barry Hahn

“…Frequent indications for transfer were nontraumatic neurologic (37%), pulmonary or respiratory (13%), trauma (12%), and cardiovascular (12%). Most patients were not ventilated before transport (71%). …”
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Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in the Patients with Euthyroid Hashimoto's Thyroiditis by Hacer Nur RESBER, Mumtaz TAKIR, Cundullah TORUN

“…Patients with diabetes, cardiovascular disease, chronic inflammatory disease, and malignancy were excluded from the study. …”
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Transplantation of Rat Mesenchymal Stem Cells Overexpressing Hypoxia-Inducible Factor 2α Improves Blood Perfusion and Arteriogenesis in a Rat Hindlimb Ischemia Model by Weifeng Lu, Xiaoli Chen, Yi Si, Shichai Hong, Zhengyu Shi, Weiguo Fu

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Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer’s disease by administration through an intranasal route by Anne-Claire Groo, Thomas Curel, Aurélie Malzert-Fréon, Line Séguy, Ophélie Bento, Sophie Corvaisier, Thomas Culerier, Romain Legrand, Noëlle Callizot, Alexandre Henriques, Georgia Culley, Sylvie Claeysen, Christophe Rochais, Patrick Dallemagne

“…Indeed, even if the latter is more selective than other β2-mimetics towards bronchial β2-AR, cardiovascular effects (tachycardia, arrhythmias…) could occur upon cardiac β1-AR activation. …”
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Educational intervention on high blood pressure aimed at childbearing age women from a doctor's office. Nuevitas, 2020-2023 by Mayra Pérez Basulto, Arvelio Adán Sánchez, Julio Michel Arias Manganelly, Olenis Alicia Aldana Ramos, Sheela Yalis Armenteros Salgado, Maigret Calderón Cruz

“…<p><strong>Foundation</strong>: high blood pressure constitutes a cardiovascular system disease, in addition to being considered a major modifiable risk factor by the World Health Organization; and a serious health problem to be solved throughout the world. …”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…The progression of CKD leads to significant complications, including cardiovascular disease, anemia, and metabolic bone disorders. …”
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Short-Term Health Impact Assessment of Urban PM10 in Bejaia City (Algeria) by Fatima Benaissa, Cara Nichole Maesano, Rezak Alkama, Isabella Annesi-Maesano

“…We used Health Impact Assessment (HIA) to analyze the impact on a given population’s health outcomes in terms of all-causes mortality and respiratory and cardiovascular hospitalizations attributable to short-term exposure to particulate matter less than 10 μm diameter (PM10) in Bejaia city, for which health effects of air pollution have never been investigated. …”
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Options of dyslipidemia treatment at non-alcoholic fatty liver disease by M. V. Mayevskaya, M. A. Morozova

“…In large clinical trials it was demonstrated that the dyslipidemia significantly increases cardiovascular risks and worsens life expectancy in these patients. …”
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