Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health by Vincent J. Miller, Frederick A. Villamena, Jeff S. Volek

“…Impaired mitochondrial function often results in excessive production of reactive oxygen species (ROS) and is involved in the etiology of many chronic diseases, including cardiovascular disease, diabetes, neurodegenerative disorders, and cancer. …”
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Hip Fracture Mortality: Is It Affected by Anesthesia Techniques? by Saffet Karaca, Egemen Ayhan, Hayrettin Kesmezacar, Omer Uysal

“…We hypothesized that combined peripheral nerve block (CPNB) technique might reduce mortality in hip fracture patients with the advantage of preserved cardiovascular stability. We retrospectively analyzed 257 hip fracture patients for mortality rates and affecting factors according to general anesthesia (GA), neuraxial block (NB), and CPNB techniques. …”
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The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation by Wenqian Yu, Wenqian Yu, Siyuan Sun, Siyuan Sun, Qiang Fu

“…Metabolic syndrome (Mets) is an important contributor to morbidity and mortality in cardiovascular, liver, neurological, and reproductive diseases. …”
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Anti-Hyperlipidemic Effect of Zinc complex of Betulinic acid in High Fat Diet- Induced Hyperlipidemia by Mehwish Tayyab, Adnan Jehangir, Farhana Ayub, Nimra Ijaz, Sameer Ahmed`, Attiya Munir

“… Background: Hyperlipidemia is considered a modifiable risk factor for cardiovascular disease and atherosclerosis. Drugs of first choice, Statins, despite being well tolerable, are accompanied by many adverse effects. …”
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Potential Association of the Oral Microbiome with Trimethylamine N-Oxide Quantification in Mexican Patients with Myocardial Infarction by Paulina Hernández-Ruiz, Alma R. Escalona Montaño, Luis M. Amezcua-Guerra, Héctor González-Pacheco, Elena Niccolai, Amedeo Amedei, María M. Aguirre-García

“…One of them is the oral microbiota translocation into the bloodstream, liver, and gut, promoting a host dysbiosis and triggering the presence of some metabolites such as trimethylamine N-oxide (TMAO), known as a risk marker for cardiovascular disease, and especially the myocardial infarction (MI). …”
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Preimplantation Genetic Diagnosis in Marfan Syndrome by N. F. Vlahos, O. Triantafyllidou, N. Vitoratos, C. Grigoriadis, G. Creatsas

“…Marfan syndrome (MFS) is a systemic hereditable disorder of the connective tissue with mainly cardiovascular manifestations, such as aortic dilatation and dissection. …”
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Epidemiological Research Advances in Vascular Calcification in Diabetes by Haipeng Yao, Zhen Sun, Guangyao Zang, Lili Zhang, Lina Hou, Chen Shao, Zhongqun Wang

“…The incidence of vascular calcification in patients with diabetes is much higher than that in nondiabetic patients, representing a critical cause of cardiovascular events in patients with diabetes. Because basic research on the clinical transformation of vascular calcification has yet to be conducted, this study systematically expounds on the risk factors for vascular calcification, vascular bed differences, sex differences, ethnic differences, diagnosis, severity assessments, and treatments to facilitate the identification of a new entry point for basic research and subsequent clinical transformation regarding vascular calcification and corresponding clinical evaluation strategies.…”
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Rare but Not so Rare? The Evolving Spectrum of Whipple's Disease by John M Conly, B Lynn Johnston

“…However, digestive symptoms are often preceded for months or years by other symptoms, the most common being arthralgia, although cardiovascular, neurological or pulmonary involvement may be more prominent at times. …”
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Aquaporin-2 in the early stages of the adenine-induced chronic kidney disease model. by Lucas H Oronel, Maria Ortiz, Carolina Yarza, Sofía Gayone, Carlos Davio, Mónica Majowicz, Maria Florencia Albertoni Borghese

“…Moreover, CKD is associated with impaired life quality, increased risk for cardiovascular diseases, and reduced life expectancy. …”
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Blood Pressure Control at Rest and during Exercise in Obese Children and Adults by Konstantina Dipla, George P. Nassis, Ioannis S. Vrabas

“…The hemodynamic responses to exercise have been studied to a great extent over the past decades, and an exaggerated blood pressure response during an acute exercise bout has been considered as an indicator of cardiovascular risk. Obesity is a major factor influencing the blood pressure response to exercise since evidence indicates that the arterial pressure response to exercise is exacerbated in obese compared with lean adults. …”
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Role of Matrix Metalloproteinase-2 in the Development of Atherosclerosis among Patients with Coronary Artery Disease by Nazirah Samah, Azizah Ugusman, Adila A. Hamid, Nadiah Sulaiman, Amilia Aminuddin

“…There was a significant association between MMP-2 levels and cardiovascular disease with MMP-14 levels, which is a pro-MMP-2 activator. …”
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Physiological Stimulation of the Synthesis of Preelastic Fibers in the Dermis of a Patient with Fibrosis by Jose Maria Pereira de Godoy, Lívia Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy, Dalisio de Santi Neto

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Aneurysm of Upper Limb Arteries in Children: Report of Five Cases by Ildar Nurmeev, Dmitry Osipov, Bruce Okoye

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CONGENITAL HEART DEFECT IN A PREGNANT WOMAN (CLINICAL CASE) by Елена Валентиновна Гришкевич, Алена Васильевна Иванникова, Елена Николаевна Орлова, Елена Владимировна Рудаева, Светлана Ивановна Елгина, Кира Борисовна Мозес, Елена Германовна Рудаева

“…The number of women with cardiovascular pathology planning and carrying a pregnancy does not decrease. …”
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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? by Kristina Harris, Amira Kassis, Geneviève Major, Chieh J. Chou

“…Recent research has shown that gut bacteria play a role in metabolic disorders such as obesity, diabetes, and cardiovascular diseases. The mechanisms by which the gut microbiota affects metabolic diseases are by two major routes: (1) the innate immune response to the structural components of bacteria (e.g., lipopolysaccharide) resulting in inflammation and (2) bacterial metabolites of dietary compounds (e.g., SCFA from fiber), which have biological activities that regulate host functions. …”
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Diabetes and Stroke Prevention: A Review by Jonathan Hewitt, Luis Castilla Guerra, María del Carmen Fernández-Moreno, Cristina Sierra

“…More encouragingly, active management of other cardiovascular risk factors has been demonstrated to prevent stroke disease and improve outcome following a stroke in the diabetic person. …”
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Qualitative and Quantitative Evaluation of Chemical Constituents from Shuanghuanglian Injection Using Nuclear Magnetic Resonance Spectroscopy by Ziyan Wang, Zuoyuan Wang, Miaomiao Jiang, Jing Yang, Qingfen Meng, Jianli Guan, Maoling Xu, Xin Chai

“…Guided by the approach of network pharmacology, the potential activities were briefly predicted for seven primary metabolites except for formic acid, such as anti-inflammation, antioxidation, and cardiovascular protection. The focused primary metabolites were quantified by a proton nuclear magnetic resonance (1H-NMR) method, which was verified with good linearity and satisfactory precision, repeatability, stability, and accuracy (except for myo-inositol with mean recovery at 135.78%). …”
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Transvestism Recognized in Ehlers-Danlos Syndrome: Report of Two Cases by Hiroki Ishiguro, Naomi Honobe, Takefumi Suzuki, Mariko Tamai, Takaya Nakane

“…Ehlers-Danlos syndrome (EDS) comprises a series of rare hereditary connective tissue diseases characterized by musculoskeletal, skin, and cardiovascular involvements. EDS may be associated with physical as well as psychological pain that can lead to psychiatric problems. …”
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Sitagliptin: a potential drug for the treatment of COVID-19? by Bardaweel Sanaa K., Hajjo Rima, Sabbah Dima A.

“…We conclude that sitagliptin may be beneficial for the treatment of COVID-19 disease, either as monotherapy or in combination with other therapies, especially for diabetic patients and patients with pre-existing cardiovascular conditions who are already at higher risk of COVID-19 mortality.…”
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Association between Hypertension and Periodontitis: Possible Mechanisms by Xin-Fang Leong, Chun-Yi Ng, Baharin Badiah, Srijit Das

“…Hypertension is one of the major risk factors for cardiovascular diseases. Oxidative stress and endothelial dysfunction are among the critical components in the development of hypertension. …”
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