The association of systemic immune-inflammation index with incident breast cancer and all-cause mortality: evidence from a large population-based study by Yu Li, Yu Li, Meng Yu, Ming Yang, Jingqi Yang

“…The Systemic Immune-Inflammation Index (SII), a novel marker derived from routine blood counts, has been suggested as a predictor of all-cause mortality and cardiovascular mortality. However, its predictive value in a nationwide representative population, particularly for breast cancer incidence and mortality, is not well-established.MethodsThis study aimed to assess the association of SII and the risk of breast cancer incidence and all-cause mortality in breast cancer patients within the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. …”
Get full text

CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

Get full text

Polymorphisms in the Glucagon-Like Peptide 1 Receptor (GLP-1R) Gene Are Associated with the Risk of Coronary Artery Disease in Chinese Han Patients with Type 2 Diabetes Mellitus: A... by Xiaowei Ma, Ran Lu, Nan Gu, Xiaowei Wei, Ge Bai, Jianwei Zhang, Ruifen Deng, Nan Feng, Jianping Li, Xiaohui Guo

“…Glucagon-like peptide 1 (GLP-1) bestows protective effects upon the cardiovascular system through direct cardiovascular interactions or by improvements to metabolic function. …”
Get full text

Comparative Efficacy and Safety of Cardio-Renoprotective Pharmacological Interventions in Chronic Kidney Disease: An Umbrella Review of Network Meta-Analyses and a Multicriteria De... by Ioannis Bellos, Smaragdi Marinaki, Pagona Lagiou, Vassiliki Benetou

“…GLP1a and ns-MRA were also associated with significant reductions in cardiovascular and kidney-specific composite outcomes. …”
Get full text

Metabolic Syndrome May Not be a Good Predictor of Coronary Artery Disease in the Iranian Population: Population-Specific Definitions are Required by Mahmoud Ebrahimi, Seyyed Mohammad Reza Kazemi-Bajestani, Majid Ghayour-Mobarhan, Mohsen Moohebati, Roghaye Paydar, Mohsen Azimi-Nezhad, Habib Ollah Esmaily, Gordon A. A. Ferns

Get full text

Prophylactic ECMO Support during Elective Coronary Percutaneous Interventions in High-Risk Patients: A Single-Center Experience by Claudiu Ungureanu, Marc Blaimont, Hugues Trine, Pierre Henin, Romain Courcelle, Yves Laurent, Patrick Van Ruyssevelt, Caroline Lepièce, Vincent Huberlant

“…Primary endpoints were in-hospital and 3- year major adverse cardiovascular and cerebrovascular event (MACCE) rates. …”
Get full text

Clinical Validation of the Defining Characteristics of the Nursing Diagnosis ‘Activity Intolerance’ in Patients With Acute Coronary Syndrome by Diana Isabel Cáceres Rivera, Luz Mileyde Jaimes Rojas, Luisa Yaneth Cristancho Zambrano, Jennifer Vanesa Acosta Barón, Diana Ivonne Cañon Gómez, Lyda Z. Rojas

Get full text

Sex-Specific Differences in the Pathophysiology of Hypertension by Hannah Zhang, Pawan K. Singal, Amir Ravandi, Inna Rabinovich-Nikitin

Get full text

Marcadores bioquímicos de aterosclerosis subclínica en pacientes con diabetes mellitus tipo 2 by Caridad Osorio Sosa, Leonar Luis Nápoles Acosta, Alfredo Salvador Vallés Gamboa, Alberto Caballero Laguna

“…<br /><strong>Conclusiones:</strong> hubo una relación directa entre los valores alterados de la proteína C reactiva de alta sensibilidad y el riesgo cardiovascular global en los pacientes estudiados.…”
Get full text

Sex Disparity in Characteristics, Management, and In-Hospital Outcomes of Patients with ST-Segment Elevated Myocardial Infarction: Insights from Henan STEMI Registry by Shan Wang, You Zhang, Qianqian Cheng, Datun Qi, Xianpei Wang, Zhongyu Zhu, Muwei Li, Junhui Zhang, Dayi Hu, Chuanyu Gao, On behalf of Henan STEMI registry study group

“…Women experienced worse in-hospital outcomes, and age and cardiovascular risk factors were major factors influencing sex-related differences. …”
Get full text

Evolving Bioprosthetic Tissue Calcification Can Be Quantified Using Serial Multislice CT Scanning by B. Meuris, H. De Praetere, W. Coudyzer, W. Flameng

Get full text

Virgin and photo-degraded microplastics induce the activation of human vascular smooth muscle cells by Elisa Persiani, Antonella Cecchettini, Sofia Amato, Elisa Ceccherini, Ilaria Gisone, Agnese Sgalippa, Chiara Ippolito, Valter Castelvetro, Tommaso Lomonaco, Federico Vozzi

“…Increasing evidence shows that MPs impact vascular function, with recent studies finding MPs in atheromas linked to cardiovascular events. Since vascular smooth muscle cells (VSMCs) are crucial to maintaining vascular function, this study examined how MPs activate VSMCs, leading to cardiovascular diseases like atherosclerosis and vascular calcification. …”
Get full text

The Role of Angiotensin Antagonism in Coronary Plaque Regression: Insights from the Glagovian Model by Abdul H. Alkatiri, Doni Firman, Amir A. Alkatiri, Paskalis I. Suryajaya, Albert Sudharsono

“…The benefit of antagonizing the effect of the renin angiotensin aldosterone system (RAAS), notably by the use of angiotensin-converting enzyme inhibitor (ACEi) and angiotensin II type 1 receptor blocker (ARB) for coronary artery disease (CAD), has been demonstrated in multiple studies, which may be attributed to their ability to inhibit the deleterious effect of RAAS to the cardiovascular system. It is well known that angiotensin II (Ang II) plays a vital role in atheromatous plaque formation and progression through multiple pathways, including inflammatory and arterial remodeling aspects. …”
Get full text

Prevalence of Microalbuminuria in Adult Patients with Sickle Cell Disease in Eastern Saudi Arabia by Ahmed M. Alkhunaizi, Adil A. Al-Khatti, Mansour A. Alkhunaizi

“…In addition to the renal consequences, MA is linked to cardiovascular complications. Periodic screening and early detection of MA allow early intervention that may reduce the risk of progression to advanced renal failure and cardiovascular diseases. …”
Get full text

Long-term outcomes of radiofrequency ablation and cyanoacrylate closure for treatment of small saphenous veins by Ahmet Kayan, Ali Fuat Karacuha, Nur Dikmen, Cagdas Baran, Mustafa Sirlak

Get full text

Peripherally Embolizing Aortic Thrombus: The Work-Up, Management, and Outcome of Primary Aortic Thrombus by Ramy Mando, Robert Gemayel, Ashish Chaddha, Julian J. Barbat, Elvis Cami

Get full text

Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome by P. Stiefel, A. J. Vallejo-Vaz, S. García Morillo, J. Villar

“…Aldosterone facilitates cardiovascular damage by increasing blood pressure and through different mechanisms that are independent of its effects on blood pressure. …”
Get full text

Notch Regulation of Hematopoiesis, Endothelial Precursor Cells, and Blood Vessel Formation: Orchestrating the Vasculature by Vincenza Caolo, Daniel G. M. Molin, Mark J. Post

Get full text

Growth Differentiation Factor 15 and Risk of Death in Haemodialysis Patients by Christelle Calen, Seraina Von Moos, Pietro Cippà, Alexandre Mebazaa, Mattia Arrigo

“…Noninvasive identification of haemodialysis patients at high risk of cardiovascular events and death might improve their outcome. …”
Get full text

E. Coli cytotoxic necrotizing factor-1 promotes colorectal carcinogenesis by causing oxidative stress, DNA damage and intestinal permeability alteration by Michela Tozzi, Alessia Fiore, Sara Travaglione, Francesca Marcon, Gabriella Rainaldi, Elena Angela Pia Germinario, Ilenia Laterza, Simona Donati, Daniele Macchia, Massimo Spada, Omar Leoni, Maria Cristina Quattrini, Donatella Pietraforte, Sofia Tomasoni, Filippo Torrigiani, Ranieri Verin, Paola Matarrese, Lucrezia Gambardella, Francesca Spadaro, Maria Carollo, Agostina Pietrantoni, Francesca Carlini, Concetta Panebianco, Valerio Pazienza, Filomena Colella, Donatella Lucchetti, Alessandro Sgambato, Antonella Sistigu, Federica Moschella, Marco Guidotti, Olimpia Vincentini, Zaira Maroccia, Mauro Biffoni, Roberta De Angelis, Laura Bracci, Alessia Fabbri

Get full text