N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy by Sheng Wang, Chunyan Wang, Fuxia Yan, Tingting Wang, Yi He, Haobo Li, Zhengyuan Xia, Zhongjun Zhang

“…NAC significantly attenuated I/RI-induced increases in oxidative stress and cardiac apoptosis, prevented postischemic autophagy formation in diabetes, and reduced postischemic myocardial infarction (all p<0.05). …”
Get full text

Efek Loading Statin Intensitas Tinggi Sebelum Intervensi Koroner Perkutan pada Pasien Sindrom Koroner Akut: Systematic Review by Cokorda Istri Padmi Suwari, Mutiara Claudia

“…</p><p><strong>Keywords</strong>:  acute coronary syndrome, major adverse cardiac events, percutaneous coronary intervention</p><p> </p></div>…”
Get full text

Serum biochemical profile in case of cardiorenal syndrome in cats with hypertrophic cardiomyopathy by Yu. A. Vatnikov, E. D. Sotnikova, V. I. Kuznetsov, A. A. Razumova, I. V. Shchurov, O. A. Petrukhina, A. A. Rudenko

“…Cardiorenal syndrome is typically defined as dysfunction of a primarily intact kidney under the influence of a complex of pathogenetic damaging factors that arise against the background of an underlying cardiac disease. The purpose of the work is to study the biochemical profile of blood serum in cats with cardiorenal syndrome arising against the background of hypertrophic cardiomyopathy. …”
Get full text

Variation in clinical and patient‐reported outcomes among complex heart failure with preserved ejection fraction phenotypes by Kelsey M. Flint, Sanjiv J. Shah, Eldrin F. Lewis, David P. Kao

“…Rate of the TOPCAT primary outcome (cardiovascular death, aborted cardiac arrest, or heart failure hospitalization) differed by HFpEF phenotype (P < 0.001) but not by treatment arm within each HFpEF phenotype. …”
Get full text

The Effect Of Demographic Factors And Comorbidities On Ejection Fraction Outcome In Acute Myocardial Infarction Patients by Kausar Malik, Faiza Batool, Shazia Siddiq, Lubna Meraj

“…All patients aged 18 or more admitted with acute myocardial infarction confirmed by clinical, ECG findings and cardiac biomarkers were included in the study and patients with pre-existing valvular heart disease, previous history of myocardial infarction and history of cardiac surgery were excluded from the study. …”
Get full text

Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation by Min Yu, Shilin Wei, Xueyang Shen, Junjie Ying, Dezhi Mu, Xiangyang Wu, Yongnan Li

Get full text

Lysophosphatidylethanolamine improves diastolic dysfunction by alleviating mitochondrial injury in the aging heart by Guiwen Xu, Wei Xiao, Pengqi Sun, Yuanjun Sun, Xinyu Yang, Xiaomeng Yin, Yang Liu

“…Echocardiography was used to assess cardiac diastolic function in adult and aging mice treated with lysophosphatidylethanolamine (LPE) or saline. …”
Get full text

Examining anti-inflammatory therapies in the prevention of cardiovascular events: protocol for a systematic review and network meta-analysis of randomised controlled trials by George A Wells, Kevin Emery Boczar, Sheojung Shin, Kathryn A Bezzina, Aishwarya Geejo, Alexander Liam Pearson, Saba Shahab, Christophe A Fehlmann, Sarah Visintini, Rob Beanlands

“…The primary outcomes will include major adverse cardiac events (MACE), and each individual component of MACE (myocardial infarction, stroke and cardiovascular death). …”
Get full text

Memahami Patofisiologi dan Aspek Klinis Syok Hipovolemik: Update dan Penyegar by Hardisman Hardisman

“…These conditions lead to decreasing of venous return and cardiac output that cause inadequate oxygen delivery and perfusion. …”
Get full text

Association of Serum Myeloid Cells of Soluble Triggering Receptor-1 Level with Myocardial Dysfunction in Patients with Severe Sepsis by Fei Tao, Liangshan Peng, Juan Li, Yiming Shao, Liehua Deng, Huaguo Yao

“…Serum levels of sTREM-1, NT-proBNP, APACHE II score, SOFA score, cardiac index, cardiac function index, global ejection fraction, and left ventricular contractility index were measured on days 1, 3, and 7 after admission to ICU. …”
Get full text

Comparison between Rocuronium and Atracurium Effect on Blood Pressure during General Anaesthesia in Baghdad Hospital by Adel Amen Hama, Noor Faris Hoobi, Sara Emad Majeed

“…This could be cautiously in the patients with preexisting cardiac or cerebral pathology or elderly or hypertension. …”
Get full text

Clinical profile and outcomes in patients with moderate to severe aortic stenosis with or without concomitant chronic kidney disease by Jinghao Nicholas Ngiam, Ching-Hui Sia, Nicholas Wen Sheng Chew, Tze Sian Liong, Zi Yun Chang, Chi Hang Lee, Wen Ruan, Edgar Lik-Wui Tay, William Kok-Fai Kong, Huay Cheem Tan, Tiong-Cheng Yeo, Kian Keong Poh

“…Conclusion: Concomitant CKD in patients with moderate to severe AS was associated with increased mortality, more frequent admissions for cardiac failure and a lower incidence of aortic valve replacement.…”
Get full text

Positive feedback loop involving AMPK and CLYBL acetylation links metabolic rewiring and inflammatory responses by Wenke Wang, Boquan Wu, Mingjun Hao, Sichong Chen, Ruiting Cong, Wenjie Wu, Pengbo Wang, Qiaoyi Zhang, Pengyu Jia, Yuequn Song, Bo Liu, Siyao Qu, Jian-Fei Pei, Da Li, Naijin Zhang

“…Furthermore, CLYBL hypoacetylation decreased monocyte infiltration, thereby alleviating cardiac remodeling. These findings suggest that the AMPK-CLYBL acetylation positive feedback loop serves as a metabolic switch driving inflammatory response and inhibiting CLYBL-K154 acetylation may offer a promising therapeutic strategy for inflammatory response-related disorders.…”
Get full text

First report of hypoplastic left heart syndrome in 3p- syndrome and review of candidate genes by Ana Kalise Böttcher, Monique Banik Siqueira, Natasha Malgarezi, Marcela Rodrigues Nunes, Rafaella Mergener, Luisa Pigatto Kalil, Patrícia Trevisan, Paulo Ricardo Gazzola Zen

“…Comments: We identified an indirect relation between gene CAV3 and hypoplastic left heart syndrome due to its strong association with cardiomyopathies and isolated cardiac defects. Furthermore, the cytogenetic band from our case is new information for the delimitation of a critical cardiac region on 3p syndrome, a discussion that has been ongoing since 1986. …”
Get full text

Effects of Dust Storms and Climatological Factors on Mortality and Morbidity of Cardiovascular Diseases Admitted to ED by Behcet Al, Mustafa Bogan, Suat Zengin, Mustafa Sabak, Seval Kul, M. Murat Oktay, Hasan Bayram, Ertan Vuruskan

“…There was no significant association of cardiac related mortality and coinciding presence of a dust storm or higher recorded temperature. …”
Get full text

Sarco(endo)plasmic Reticulum Ca2+-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene by Angel Zarain-Herzberg, Georgina Alvarez-Fernandez

“…The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform. …”
Get full text

The Protective Effect of Beraprost Sodium on Diabetic Cardiomyopathy through the Inhibition of the p38 MAPK Signaling Pathway in High-Fat-Induced SD Rats by Jie Li, Li Peng, Hong Du, Yangtian Wang, Bin Lu, Yixin Xu, Xiaozhen Ye, Jiaqing Shao

“…After 8 weeks, we explored the role of the p38 MAPK signaling pathway in inflammation, oxidative stress, cardiac morphology, and myocardial apoptosis. Results. …”
Get full text

Mechanical Thrombectomy System for the Treatment of Intermediate-Risk Acute Pulmonary Embolism: The CLEAR Study by Wenguang Zhang, Tao Hu, Song Ding, Zhouming Wang, Tao Zhang, Hongyao Hu, Xin Fang, Honggang Pang, Mingjin Guo, Bo Yu, Hui Zhuang, Nuofu Zhang, Baoshi Han, Qiguang Wang, Mingzhi Cai, Kuan Wang, Pingfan Guo, Bin Xu, Peiliang Fang, Shengxian Tu, Yi Jiang, Hongyu Shi, Zhenwen Yang, Xinwei Han, Hongyan Tian, Jun Pu, Xiaoming Zhang

“…One patient experienced clinical deterioration within 48 hours, and none experienced major AEs, device-related pulmonary vascular injury, cardiac injury, or major bleeding within 48 hours. …”
Get full text

Elevated Troponin Serum Levels in Adult Onset Still’s Disease by Carlo Umberto Manzini, Lucio Brugioni, Michele Colaci, Maurizio Tognetti, Amelia Spinella, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…These observations suggest that early myocardial injury might be underestimated or entirely overlooked in patients with AOSD; routine cardiac assessment including troponin evaluation should be mandatory in all patients with suspected AOSD.…”
Get full text

Abdominal Aortic Occlusion and the Inflammatory Effects in Heart and Brain by Jun Xu, Sijie Li, Alexandra Wehbe, Xunming Ji, Yong Yang, Yu Yang, Linhui Qin, Feng-Yong Liu, Yuchuan Ding, Changhong Ren

“…AAO did not induce cell necrosis or apoptosis in cardiac or neurologic tissue, but it can cause inflammation in the serum, brain, and heart.…”
Get full text