Mutational Analysis of KCNQ1 Gene in Type 2 Diabetes Mellitus: A Case-control Study by Ankush Ganjewar, Ishwar B Bagoji, Sharan Badiger, Rudragouda B Bulagouda, Gurushnatappa Kadakol

“…Introduction: KCNQ1 (Potassium voltage-gated channel subfamily Q member 1) gene encodes for pore-forming subunit of a voltage-gated K+ channel that is essential for the depolarisation phase of the action potential in cardiac muscle. KCNQ1 is also associated with impaired insulin secretion in Type 2 Diabetes Mellitus (T2DM), suggesting that this impairment might underlie the diabetes susceptibility conferred by rs151290, which is associated with 30-min C-peptide levels during an Oral Glucose Tolerance Test (OGTT) and first-phase insulin secretion. …”
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A Hemodynamic-Based Evaluation of Applying Different Types of Coronary Artery Bypass Grafts to Coronary Artery Aneurysms by Haoran Wang, Hitomi Anzai, Youjun Liu, Aike Qiao, Jinsheng Xie, Makoto Ohta

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TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes by Wenrui Sun, Jianchao Zhang, Shuang Li, Wanrong Fu, Yangyang Liu, Mengduan Liu, Jianzeng Dong, Xiaoyan Zhao, Xiaowei Li

“…Results TAB2 disruption had no impact on the cardiac differentiation of iPSCs and led to confirmed TAB2 deficiency in human iPSC-derived cardiomyocytes (hiPSC-CMs). …”
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Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients by Cheng-An Chiu, Teng-Hung Yu, Wei-Chin Hung, Li-Fen Lu, Fu-Mei Chung, I-Ting Tsai, Chih-Ying Yang, Chia-Chang Hsu, Yung-Chuan Lu, Jer-Yiing Houng, Yau-Jiunn Lee, Chao-Ping Wang

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The Long-Term Change of Arrhythmias after Transcatheter Closure of Perimembranous Ventricular Septal Defects by Hongyan Zheng, Aiwen Lin, Li Wang, Yukai Xu, Zhiwei Zhang

“…Close attention should be paid to the changes of cardiac function in patients with CLBBB after VSD closure, and the severity of such arrhythmia should be taken seriously and reexamined.…”
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Catlet scoring system as a new predictor for in-stent restenosis in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting st... by Juan Wang, Mingchao Zhang, Weipeng Gan, Mingxing Xu, JiaYan Zhou, Lingfei Yang, Yongsheng Ke

“…Preliminary studies have demonstrated its superiority over the the Synergy between percutaneous coronary intervention with Taxus and Cardiac Surgery (SYNTAX) score with respect to outcome predictions for acute myocardial infarction (AMI) patients. …”
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Emergency Laparotomy in the Critically Ill: Futility at the Bedside by Niels D. Martin, Sagar P. Patel, Kristen Chreiman, Jose L. Pascual, Benjamin Braslow, Patrick M. Reilly, Lewis J. Kaplan

“…Mortality by admitting service was cardiac 71.4% (n=42), medical 70% (n=30), ACS 42% (n=50), and other 36.4% (n=22) services. …”
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Distinct phenotypes of patients and healthcare resource utilization after hospitalization for COVID-19: an observational study by Claire Marant Micallef, Manon Belhassen, Florence Ader, Valeria Martinez, Eric Van Ganse, Marjorie Bérard, Mélanie Née, Mikhail Dziadzko, Frédéric Aubrun

“…Four clusters were characterized by older patients and high proportions of comorbidities, i.e. cancer (cluster 3), mental disorders (cluster 4), cardiac insufficiency (cluster 5) and respiratory failure (cluster 6). …”
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Surgical treatment of patients with renal cell cancer complicated by specific (tumor) and non-specific thrombosis of the inferior Vena cava by N. V. Vorobev, F. S. Ashyrova, M. P. Golovashchenko, L. O. Petrov, A. D. Kaprin

“…This article presents a clinical case of surgical treatment of a patient with renal cell cancer complicated by massive specific (tumor) and non-specific thrombosis in the presence of reduced parenchymalexcretory function of the contralateral kidney and severe cardiac pathology. Goal: to share experience and demonstrate the results of successful surgical treatment of renal cell carcinoma.…”
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Early experience of Sacubitril–Valsartan in heart failure with reduced ejection fraction in real‐world clinical setting by Charlotte Nordberg Backelin, Michael Fu, Charlotta Ljungman

“…The patients who were initiated were younger (65 years), more often had dilated cardiomyopathy (31%), more often were on guideline‐directed medical therapy, and had a higher frequency of cardiac resynchronization therapy and implantable cardioverter–defibrillator compared with the patients who did not receive Sac/Val. …”
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Using a digital health intervention “INTERCEPT” to improve secondary prevention in coronary heart disease (CHD) patients: protocol for a mixed methods non-randomised feasibility st... by Catriona Jennings, Irene Gibson, Marissa Corcoran, John William McEvoy, Lis Neubeck, Lisa Hynes, Faisal Sharif, David Wood, Andrew W Murphy, Molly Byrne

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Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe by Lucinda A. Harris, Stephanie L. Hansel, Elizabeth Rajan, Komandoor Srivathsan, Robert Rea, Michael D. Crowell, David E. Fleischer, Shabana F. Pasha, Suryakanth R. Gurudu, Russell I. Heigh, Arthur D. Shiff, Janice K. Post, Jonathan A. Leighton

“…The presence of an implantable electromechanical cardiac device (IED) has long been considered a relative contraindication to the performance of video capsule endoscopy (CE). …”
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Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time by André Luiz Musmanno Branco Oliveira, Gabriel Dias Rodrigues, Gabriel Dias Rodrigues, Bruno Moreira Silva, Philippe de Azeredo Rohan, Pedro Paulo da Silva Soares

“…Pulse oxygen saturation (SpO2), R-R intervals, cardiac output, blood pressure (BP), and ventilatory data were continuously recorded during spontaneous breathing. …”
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Changes in oxygen uptake kinetics after exercise caused by differences in loading pattern and exercise intensity by Yuri Ichikawa, Tomoko Maeda, Tetsuya Takahashi, Kohei Ashikaga, Shiori Tanaka, Yuki Sumi, Haruki Itoh

“…Submaximal exercise tests may be considered as convenient methods for evaluating exercise tolerance in patients with cardiac failure.…”
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Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

“…Abstract Background Fulminant myocarditis (FM), a critical cardiac disease, is characterised by atypical initial symptoms and rapid progression and tends to lead to cardiomyocyte degeneration or necrosis. …”
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Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting by Murat Selçuk, Tufan Çınar, Faysal Şaylık, Selami Doğan, Ismail Selçuk, Ahmet L. Orhan

“…Objective: Inflammation plays an important role in the initiation of postoperative atrial fibrillation (PoAF) in individuals undergoing cardiac surgery, Thus, this study aimed to investigate the predictive value of the systemic immune inflammation index (SII) to develop PoAF in such patients. …”
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Dexamethasone Prophylaxis in Pediatric Open Heart Surgery Is Associated with Increased Blood Long Pentraxin PTX3: Potential Clinical Implications by Franco Lerzo, Giuseppe Peri, Andrea Doni, Paola Bocca, Fabio Morandi, Angela Pistorio, Anna Maria Carleo, Alberto Mantovani, Vito Pistoia, Ignazia Prigione

“…Dexamethasone prophylaxis in pediatric patients undergoing CPB for cardiac surgery is associated with a significant increase of blood PTX3 that could contribute to decreasing inflammatory parameters and improving patient clinical outcome.…”
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Correction: HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

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Genetic Analysis of in Korean Patients Associated with Atrioventricular Conduction Block by Hyoung Seob Park, Yoon Nyun Kim, Young Soo Lee, Byung Chun Jung, Sang Hee Lee, Dong Gu Shin, Yongkeun Cho, Myung Hwan Bae, Sang Mi Han, Myung Hoon Lee

“…We enrolled 113 patients with AVB and 80 normal controls with no cardiac symptoms. DNA was isolated from the peripheral blood, and all exons (exon 2-exon 28) except the untranslated region and exon-intron boundaries of the SCN5A gene were amplified by multiplex PCR and directly sequenced using an ABI PRISM 3100 Genetic Analyzer. …”
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The experience of bodily image for patients with left ventricular assist device by Irena Milaniak, Emilia Witkowska, Marta Cebula, Paulina Tomsia, Grzegorz Wasilewski, Izabela Górkiewicz-Kot, Sylwia Wiśniowska-Śmiałek, Michał Kaleta, Karol Wierzbicki, Karol Wierzbicki

“…IntroductionMechanical Cardiac Support and Left Ventricular Assist Devices (LVAD) have been demonstrated to prolong Heart Failure patients' survival and improve their quality of life. …”
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