Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project by Luigi Sciarra, Saverio Iacopino, Giuseppe Arena, Claudio Tondo, Paolo Pieragnoli, Giulio Molon, Massimiliano Manfrin, Antonio Curnis, Antonio Dello Russo, Giovanni Rovaris, Giuseppe Stabile, Leonardo Calò, Gabriele Boscolo, Roberto Verlato

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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…There is scarce information about the relationships between postoperative pulmonary hemodynamics, inflammation, and outcomes in pediatric patients with congenital cardiac communications undergoing surgery. We prospectively studied 40 patients aged 11 (8–17) months (median with interquartile range) with a preoperative mean pulmonary arterial pressure of 48 (34–54) mmHg who were considered to be at risk for postoperative pulmonary hypertension. …”
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Common Risk Factors of Myocardial Infarction and Some Socio Demographic Characteristics in Sulaimani City by Bayan Omar Sharif, Samir Y. Lafi

“…The current study’s main aims were to explore the potential association between several predisposing factors and heart attack in Sulaimani, Iraq, and to some socio demographic in this participant. 165 contributors who were attending to the Cardiac Specialty Hospital, (Coronary Care Unit), and they were definitely diagnosed as having MI participated in the current study between 2015 and 2016; in Sulaimani, Iraq.  …”
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Evaluation of 30-day mortality in patients undergoing gastrointestinal endoscopy in a tertiary hospital: a 3-year retrospective survey by Philippe Bichard, Jean-Louis Frossard, Laurent Spahr, Nicolas Goossens, Olivier Chatelanat, Laurent Bochatay, Caroline Bastid

“…Major causes of death were oncological progression (72/251; 28.68%), cardiopulmonary failure or cardiac arrest of unkown origin (62/251; 24,7%) and liver failure (20/251; 7.96%). …”
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Diagnosis of Coxiella burnetii endocarditis by using nanopore targeted sequencing: a case report by Xinsheng Yan, Qimei Wei, Tingting Liu, Dong Wang, Zhenlu Zhang

“…Case presentation The present study reports the case of a 57-year-old male patient who was admitted with a diagnosis of severe aortic stenosis. Cardiac computed tomography (CT) angiography revealed a diastolic aortic valve malformation with significant leaflet thickening, calcification and pseudoaneurysm formation, the etiology of which was considered to be due to infectious possibilities. …”
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Evaluation and Optimization Research on the Spatial Distribution of Automated External Defibrillators Based on a Genetic Algorithm: A Case Study of Central Urban District of Nanjin... by Ge Shi, Jiahang Liu, Chuang Chen, Jingran Zhang, Jinghai Xu, Yu Chen, Jiaming Na, Wei Chen

“…Automated external defibrillators (AEDs) are portable emergency medical devices critical for resuscitating individuals experiencing sudden cardiac arrest. The installation of AEDs in public spaces is essential for enhancing society’s emergency response capabilities. …”
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Assessment of Clinical Features in HIV-Infected Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention in China by Ying Liu, Yongfu Chen, Yiwei Hao, Jing Xiao, Bei Li, Leidan Zhang, Junyan Han, Hongxin Zhao

“…In addition, the risk of major adverse cardiac and cerebrovascular events at 1 year was similar in both groups. …”
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Daily Chronic Intermittent Hypobaric Hypoxia Does Not Induce Chronic Increase in Pulmonary Arterial Pressure Assessed by Echocardiography by Jeremias Götschke, Pontus Mertsch, Nikolaus Kneidinger, Diego Kauffmann-Guerrero, Jürgen Behr, Rudolf Maria Huber, Frank Reichenberger, Katrin Milger

“…LA echocardiography showed normal right and left cardiac dimensions and function in all subjects. Systolic PAP (sPAP) and tricuspid annular plane systolic excursion (TAPSE) at rest were similar in both groups. …”
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Causal Inference for Hypertension Prediction With Wearable E lectrocardiogram and P hotoplethysmogram Signa... by Ke Gon g, Yifan Chen, Xinyue Song, Zhizhong Fu, Xiaorong Ding

“…Hypertension can be detected in a timely manner with cardiac signals, such as through an electrocardiogram (ECG) and photoplethysmogram (PPG) , which can be observed via wearable sensors. …”
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Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…This can lead to myocardial fibrosis and apoptosis and thus eccentric cardiac hypertrophy and impaired contractile function. …”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…The animals were anaesthetized and sacrificed to obtain blood by cardiac puncture. Preliminary phytochemical analysis of CA showed the content of tannins (5.72±0.00), saponins (12.49±0.021), alkaloids (17.45 ±0.65), flavonoids  (23.72 ±0.02), cyanogenic glycosides (0.75 ±0.10) and phytate (1.97 ±0.06). …”
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A Cocktail Method for Promoting Cardiomyocyte Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells by Qing Gao, Maojuan Guo, Xijuan Jiang, Xiantong Hu, Yijing Wang, Yingchang Fan

“…Real-time qPCR and Western blotting analyses showed that cTnT, alpha-cardiac actin, mef-2c, Cx43, and GSK-3beta expression increased while beta-catenin expression decreased. …”
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The Impact of Smoking on Clinical Outcomes after Percutaneous Coronary Intervention in Women Compared to Men by Seyyed Saeed Mohammadi, Mohammad Javad Zibaeenezhad, Mehrab Sayadi, Soorena Khorshidi, Ehsan Hadiyan, Iman Razeghian-Jahromi

“…Participants were followed up seeking for major adverse cardiac events (MACE) including revascularization (PCI or coronary artery bypass grafting), myocardial infarction, and coronary death in three time intervals according to the time of index PCI (short term: up to 24 hours, mid-term: 24 hours to less than 6 months, and long term: more than 6 months). …”
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Synthesized 18-Lead Electrocardiogram in Diagnosing Posterior Stemi-Equivalent Acute Coronary Syndrome in Patients with NSTEMI by Tomoki Horie, Rikuta Hamaya, Tomoyo Sugiyama, Hidenori Hirano, Masahiro Hoshino, Yoshihisa Kanaji, Tetsumin Lee, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta

“…After adjustment for confounders, sV7-9 STE was significantly associated with a 308% (95% CI: 78–834%) increase in peak high-sensitivity cardiac troponin I (p=0.001). Conclusions. SV7-9 STE had sole preprocedural diagnostic utility in detecting LCx STEMI-equivalent ACS with greater myocardial damage among patients with 12 ECG-based NSTEMI. …”
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Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…The animals were anaesthetized and sacrificed to obtain blood by cardiac puncture. Preliminary phytochemical analysis of CA showed the content of tannins (5.72±0.00), saponins (12.49±0.021), alkaloids (17.45 ±0.65), flavonoids  (23.72 ±0.02), cyanogenic glycosides (0.75 ±0.10) and phytate (1.97 ±0.06). …”
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Model for End-Stage Liver Disease Score Predicts the Mortality of Patients with Coronary Heart Disease Who Underwent Percutaneous Coronary Intervention by You Chen, Min Han, Ying-Ying Zheng, Feng Zhu, Aikebai Aisan, Tunike Maheshati, Yi-Tong Ma, Xiang Xie

“…The primary endpoint was long-term mortality including all-case mortality (ACM) and cardiac mortality (CM). Secondary endpoints included bleeding events, readmission, major adverse cardiovascular events (MACE), major adverse cardiovascular, and cerebrovascular events (MACCE). …”
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Psychometric Validation of the German Version of the Rapid Assessment of Physical Activity (RAPA): A Secondary Analysis of Cross‐Sectional Survey Data by Hannah McGowan, Rik Crutzen, Tari Topolski, Stefan Tino Kulnik

“…Methods We conducted a psychometric validation of a new German translation of the RAPA by performing a secondary analysis of survey data from 234 former cardiac rehabilitation patients (mean [SD] age 69 ± 11 years, 23% female) in Austria. …”
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A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation by Shuhua Luo, Menglin Tang, Lei Du, Lina Gong, Jin Xu, Youwen Chen, Yabo Wang, Ke Lin, Qi An

“…Extracorporeal circulation (ECC) is necessary for conventional cardiac surgery and life support, but it often triggers systemic inflammation that can significantly damage tissue. …”
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Mitochondrial trifunctional protein deficiency caused by a deep intronic deletion leading to aberrant splicing by Thomas Cassini, Sarah Silverstein, Molly Behan, Cynthia J. Tifft, May Christine Malicdan, David R. Adams, Undiagnosed Diseases Network, Sun‐Young Ahn, Debra S. Regier

“…Abstract Trifunctional protein deficiency (TFP) is a disorder of fatty acid beta‐oxidation associated with metabolic, cardiac, and liver dysfunction in severe forms. We present two siblings diagnosed by newborn screening and confirmed by biochemical testing at birth. …”
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Cost-Effectiveness of the Prenatal Detection of Congenital Heart Diseases: A Systematic Literature Review by Darío Londoño Trujillo, Paula A. Castro García, Kristian K. Rojas López, Karen J. Moreno-Medina, María T. Dominguez Torres, Rodolfo J. Dennis Verano, Nestor F. Sandoval Reyes

“…In addition to perinatal morbidity and mortality, it entails long-term consequences such as multiple surgeries, prolonged hospitalizations, lifelong cardiac follow-up, reduced quality of life, risk of heart failure, and premature mortality in adulthood. …”
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