Nasogastric Tube Feeding-Induced Esophageal Bezoar: Case Description by Jad A. Degheili, Mikhael G. Sebaaly, Ali H. Hallal

“…A 69-year-old male presented following cardiac arrest postmyocardial infarction. Patient sustained anoxic brain injury after resuscitation, rendering him ventilator dependant along with nasogastric tube feeding, initially. …”
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Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications: insights from a national cohort study by Muhammad Shahzil, Ammad Javaid Chaudhary, Saad Javaid, Vishali Moond, Gokturk Tepe, Muhammad Saad Faisal, Muhammad Ali Khaqan, Anas Kutait

“…Secondary outcomes showed patients with AP-CE had a significantly increased risk of serious complications, particularly cardiac arrest (aOR 64.24; 95% CI 24.27–170.02), and higher hospital resource utilization. …”
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Efficacy and Safety of High-dose versus Standard-dose Prazosin in Paediatric Scorpion Envenomation: A Single-blinded Randomised Controlled Study by Apoorva Gayatri Abbadi, Hidaytullah R Bijapure, Chandrika R Doddihal, Bhavana B Lakhkar, Y Rohith, VJ Prakash, Kumar BM Prasanna, Mallanagouda Patil

“…As children have a small body surface area, they are prone to more serious cardiac, respiratory and neurological complications. …”
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The HFA‐PEFF score identifies ‘early‐HFpEF’ phenogroups associated with distinct biomarker profiles by Michiel T.H.M. Henkens, Anne‐Mar vanOmmen, Sharon Remmelzwaal, Gideon B. Valstar, Ping Wang, Job A.J. Verdonschot, Mark R. Hazebroek, Leonard Hofstra, Vanessa P.M. vanEmpel, Joline W.J. Beulens, Hester M. denRuijter, Stephane R.B. Heymans

“…Methods and results Subjects referred to the Cardiology Centers of the Netherlands, location Utrecht, with non‐acute possibly cardiac‐related symptoms (such as dyspnoea or fatigue) were prospectively enrolled in the HELPFul cohort (N = 507) and were included in the current analysis. …”
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Thoraco-abdominal normothermic regional perfusion does not restore cerebral blood flow or electrical activity despite collateral supra-aortic blood flow in a porcine model by Matthieu Glorion, MD MSc, Joel Neves Briard, MD MSc, Louise Roquebert, Sabina Pizzi, Ahmed Menaouar, PhD, Mélanie Borie, MSc, Manon Robert, MSc, Dang Khoa Nguyen, MD PhD, Michaël Chassé, MD PhD, Basil Nasir, MD, Pasquale Ferraro, MD, Shant Der Sarkissian, PhD, MBA, Pierre-Emmanuel Noly, MD PhD, Nicolas Noiseux, MD PhD

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Bisphenol S exposure interrupted human embryonic stem cell derived cardiomyocytes differentiation through ER-NF-κB/ERK signaling pathway by Yongru Zhou, Lin Tian, Liang Wang, Wenjing Wu, Baofang Liang, Wei Xiong, Lishi Zhang, Xiaomeng Li, Jinyao Chen

“…Bisphenol S (BPS) has been put into production as a wide range of Bisphenol A (BPA) alternatives, while little is known regarding its cardiac developmental toxicity. To explore the effect of BPS on cardiomyocyte differentiation and its mechanism, our study established the human embryonic stem cell-cardiomyocyte differentiation model (hESC-CM), which was divided into early period of differentiation (DP1:1–8d), anaphase period of differentiation (DP2:9–16d) and whole stage of differentiation (DP3:1–16d) exposed to human-related levels of BPS. …”
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Functional Improvement Trajectories After Surgery (FIT After Surgery) study: protocol for a multicentre prospective cohort study to evaluate significant new disability after major... by E Jacobsohn, Duminda N Wijeysundera, Gerald Lebovic, M Davis, Martine T E Puts, Shabbir M H Alibhai, Karim S Ladha, C Wong, Daniel I McIsaac, C Hanley, T Barnes, G Lorello, N Siddiqui, P Serrano, Tyler R Chesney, S Choi, J Van Vlymen, D Sussman, D Macdonald, P Jüni, Emily Hladkowicz, C David Mazer, M Bosch, CD Mazer, A Jerath, J Pazmino-Canizares, E Kennedy, R Spence, V Lyon, Alice C Wei, Julian F Daza, Sahar Ehtesham, Janet M van Vlymen, DN Wijeysundera, KS Ladha, JF Daza, G Mattina, E Hladkowicz, M Tessier, S Ehtesham, S Nnorom, SMH Alibhai, M Puts, G Lebovic, TR Chesney, AC Wei, S Drozdz, M Louridas, RH Breau, M Lalu, S Abdellatif, S Gagne, E Duceppe, K Zarnke, D Dumerton, M Karizhenskaia, H El Beheiry, F Bonazza, A Zahavich, M Thorleifson, S L Russell, H Bagry, SY MacDonell, J Dale-Gandar, L Kaustov, A Fleet, E Al Azazi, M Parotto, S A McCluskey, H Poonawala, D Dillane, Di McIsaac, S Avramescu, S Shabeen

“…We propose that postoperative disability is an important patient-centred outcome to measure intermediate-to-long recovery after major surgery in older adults.Methods and analysis The Functional Improvement Trajectories After Surgery (FIT After Surgery) study is a multicentre cohort study of 2000 older adults (≥65 years) having major non-cardiac surgery. Its objectives are to characterise the incidence, trajectories, risk factors and impact of new significant disability after non-cardiac surgery. …”
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Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy by Xuehui Fan, Guoqiang Yang, Yinuo Wang, Haojie Shi, Katja Nitschke, Katherine Sattler, Mohammad Abumayyaleh, Lukas Cyganek, Philipp Nuhn, Thomas Worst, Bin Liao, Gergana Dobreva, Daniel Duerschmied, Xiaobo Zhou, Ibrahim El-Battrawy, Ibrahim Akin

“…Methods Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) were treated with epinephrine (Epi) or exosomes (Exo) from Epi-treated human cardiac microvascular endothelial cells (HCMECs) or Exo derived from HCMECs transfected with miR-126-3p. …”
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Role and prognostic value of growth differentiation factor 15 in patient of heart failure with preserved ejection fraction: insights from the PURSUIT-HFpEF registry by Tetsuhisa Kitamura, Shungo Hikoso, Takahisa Yamada, Yoshio Yasumura, Akito Nakagawa, Toshihiro Takeda, Hirota Kida, Akihiro Sunaga, Tomoharu Dohi, Katsuki Okada, Daisaku Nakatani, Yasushi Matsumura, Yasushi Sakata, Shunsuke Tamaki, Takaharu Hayashi, Yoshiharu Higuchi, Masaharu Masuda, Mitsutoshi Asai, Toshiaki Mano, Hisakazu Fuji, Daisaku Masuda, Shizuya Yamashita, Masami Sairyo, Yusuke Nakagawa, Haruhiko Abe, Yasunori Ueda, Kunihiko Nagai, Masamichi Yano, Masami Nishino, Jun Tanouchi, Yoh Arita, Shinji Hasegawa, Takamaru Ishizu, Minoru Ichikawa, Yuzuru Takano, Eisai Rin, Tetsuya Watanabe, Shiro Hoshida, Masahiro Izumi, Hiroyoshi Yamamoto, Hiroyasu Kato, Kazuhiro Nakatani, Mayu Nishio, Keiji Hirooka, Takahiro Yoshimura, Akihiro Tani, Yasushi Okumoto, Yasunaka Makino, Katsuomi Iwakura, Yoshiyuki Kijima, Takashi Kitao, Masashi Fujita, Koichiro Harada, Masahiro Kumada, Osamu Nakagawa, Ryo Araki, Takayuki Yamada, Fusako Sera, Kei Nakamoto, Hidetaka Kioka, Tomohito Ohtani, Nobuyuki Ogasawara, Yukinori Shinoda, Koichi Tachibana, Yohei Sotomi, Taiki Sato, Yuji Yasuga, Toshinari Onishi, Kazunori Kashiwase, Ryu Shutta, Masahiro Seo, Yuki Matsuoka, Yasuhiro Akazawa, Daisuke Sakamoto

“…GDF15 significantly correlated with cardiac burden, anaemia, renal dysfunction and inflammation. …”
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Magnetic Resonance Imaging in a Patient with a Dual Chamber Pacemaker by Lynne Martina Millar, Andrew George Robinson, Maurice Thomas O'Flaherty, Niall Eames, Nicola Johnston, Gary Heyburn

“…This has become increasingly difficult in clinical practice as insertion of pacemakers and implantable cardiac defibrillators is at an all time high. Here we outline a case where a 71-year-old male patient with a permanent pacemaker needed to have an MRI scan to ascertain the aetiology of his condition and help guide further management. …”
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Successful Damage Control Resuscitation with Resuscitative Endovascular Balloon Occlusion of the Aorta in a Pediatric Patient by Yoonjung Heo, Sung Wook Chang, Dong Hun Kim

“…A 7-year-old male patient experienced cardiac arrest after a motor vehicle accident. After 30 minutes of cardiopulmonary resuscitation, spontaneous circulation was achieved. …”
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Postural Tachycardia Syndrome and Vasovagal Syncope: A Hidden Case of Obstructive Cardiomyopathy without Severe Septal Hypertrophy by Kenneth A. Mayuga, Natalie Ho, Robert W. Shields, Paul Cremer, L. Leonardo Rodriguez

“…However, an echocardiogram at our institution revealed obstructive cardiomyopathy without severe septal hypertrophy, with a striking increase in left ventricular outflow tract gradient from 7 mmHg at rest to 75 mmHg during Valsalva, with a septal thickness of only 1.3 cm. Cardiac MRI showed an apically displaced multiheaded posteromedial papillary muscle with suggestion of aberrant chordal attachments to the anterior mitral leaflet contributing to systolic anterior motion of the mitral valve. …”
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Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study by Hidayet Sal, Erhan Huseyin Comert, Yasin Semih Ekici, Turhan Aran

“…A fetal echogenic bowel was associated with major congenital malformations in 25 (%25) cases. Cardiac abnormality was the most prevalent (%7). First and second trimester vaginal bleeding history was found in 5 pregnant women. …”
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Numerical characterization of hemodynamics conditions near aortic valve after implantation of left ventricular assist device by Annalisa Quaini, Sunčica Čanić, David Paniagua

“…The use of LVADs has been associated with thrombus formation next to the aortic valve and close to the anastomosis region,especially in patients in which the native cardiac function isnegligible and the aortic valve remains closed.Stagnation points and recirculation zones have been implicated as the main fluid dynamics factors contributing to thrombus formation.The purpose of the present study was to develop and use computer simulations based on afluid-structure interaction (FSI) solver to study flow conditions corresponding to different strategies inLVAD ascending aortic anastomosis providing a scenario with the lowest likelihood of thrombus formation.A novel FSI algorithm was developed to dealwith the presence of multiple structures corresponding to different elastic properties ofthe native aorta and of the LVAD cannula.A sensitivity analysis of different variables was performed to assess their impact of flow conditionspotentially leading to thrombus formation.It was found that the location of the anastomosis closest to the aortic valve(within 4 cm away from the valve)and at the angle of 30$^\circ$ minimizes the likelihood of thrombus formation.Furthermore, it was shownthat the rigidity of the dacron anastomosis cannula plays almost no role in generating pathologicalconditions downstream from the anastomosis.Additionally, the flow analysis presented in this manuscriptindicates that compliance of the cardiovascular tissue acts as a natural inhibitor of pathological flow conditions conducive to thrombus formationand should not be neglected in computer simulations.…”
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Multi-Indices Quantification for Left Ventricle via DenseNet and GRU-Based Encoder-Decoder with Attention by Zhi Liu, Yunhua Lu, Xiaochuan Zhang, Sen Wang, Shuo Li, Bo Chen

“…At first, DenseNet is utilized to extract spatial features for each cardiac frame. Then, in order to take advantage of the time sequence information, the temporal feature for consecutive frames is encoded using gated recurrent unit (GRU). …”
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Bilateral Macular Roth Spots as a Manifestation of Subacute Endocarditis by Karolina Ceglowska, Katarzyna Nowomiejska, Agnieszka Kiszka, Michael J. Koss, Ryszard Maciejewski, Robert Rejdak

“…The patient underwent cardiac surgery with mechanical aortic valve implantation. …”
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Coupling of the Functional Stability of Rat Myocardium and Activity of Lipid Peroxidation in Combined Development of Postinfarction Remodeling and Diabetes Mellitus by S. A. Afanasiev, D. S. Kondratieva, T. Yu. Rebrova, R. E. Batalov, S. V. Popov

“…It was shown that in combined development of postinfarction cardiac remodeling of heart (PICR) with diabetes mellitus (DM) animal body weight decreased in less degree than in diabetic rats. …”
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Potential impact of coronaviruses upon cardiovascular system under COVID-19 pandemic by L.O. Tkachenko, O.A. Yepanchintseva, B.M. Todurov

“…A significant proportion of patients have cardiovascular disease and / or cardiac risk factors. The pathogenesis of the virus on the body, clinical manifestations of the disease, features of the course of infection in patients with cardiovascular disease are discussed. …”
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Leiomodin creates a leaky cap at the pointed end of actin-thin filaments. by Dmitri Tolkatchev, Garry E Smith, Lauren E Schultz, Mert Colpan, Gregory L Helms, John R Cort, Carol C Gregorio, Alla S Kostyukova

“…Using nuclear magnetic resonance data and molecular dynamics simulations, we generated the first atomic structural model of the binding interface between the tropomyosin-binding site of cardiac leiomodin and the N-terminus of striated muscle tropomyosin. …”
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Correlation of Inflammatory Markers and Disease Severity with Cardiovascular Autonomic Dysfunction in Indian Patients with Rheumatoid Arthritis by Mohan Babu Saminathan, Renuka Sharma, Arun Gogna, Anita Rani, Raj Kapoor

“…Since few studies are available regarding the status of cardiac autonomic function in RA, we planned to study the same in RA patients and correlate it with their level of inflammatory markers and disease severity. …”
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