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Association between Genetic Instability and Helicobacter pylori Infection in Gastric Epithelial Dysplasia
Published 2012-01-01“…Coexistence of H. pylori infection and MSI might be a driving force of gastric carcinogenesis.…”
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122
High Prevalence of Human Papillomavirus in Colorectal Cancer in Hispanics: A Case-Control Study
Published 2016-01-01“…Despite evidence of HPV integration into the host genome, further mechanistic analysis examining HPV oncoprotein expression and the putative role of these oncoproteins in colorectal carcinogenesis is warranted.…”
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123
Chimeric RNA in Cancer and Stem Cell Differentiation
Published 2018-01-01“…In this review, we outline proven mechanisms through which intergenically spliced chimeric RNAs are involved in carcinogenesis. We highlight their similarity to canonical chimeric RNAs resulting from gene fusions as well as their unique qualities. …”
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124
Basal Cell Carcinoma in Type 2 Segmental Darier's Disease
Published 2012-01-01“…In addition, nonmelanoma skin cancer (NMSC) arising from DD is rarely reported; however, there may be an association between DD and risk of carcinogenesis.…”
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125
Mathematical Analysis Of A Modular Network Coordinating The Cell Cycle And Apoptosis
Published 2005-07-01“…The cell-division cycle and apoptosis are key cellular processes deregulated during carcinogenesis. Recent work of Aguda and Algar suggests a modular organization of regulatory molecular pathways linking the cellular processes of division and apoptosis. …”
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126
Spatial Positioning of RET and H4 Following Radiation Exposure Leads to Tumor Development
Published 2001-01-01“…Although it has been known for a long time that radiation exposure to the cell results in extensive DNA damage, including double strand DNA breaks, the exact mechanisms of radiation-induced carcinogenesis remain unknown. Recently, a large increase in incidence of thyroid cancer was observed in children exposed to radiation after the Chernobyl nuclear accident [1]. …”
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127
Expression of ERα, ERβ and Co-Regulator PELP1/MNAR in Colorectal Cancer: Prognostic Significance and Clinicopathologic Correlations
Published 2009-01-01“…Background: Estrogen receptor β (ERβ) is abundantly expressed in colorectal tissue, but its role in colorectal carcinogenesis remains elusive. ER novel co-regulator, proline-, glutamic acid- and leucine-rich protein 1 (PELP1/MNAR) has been characterized, but its expression in colorectal carcinomas has not been investigated.…”
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128
A bird's eye view to the homeostatic, Alzheimer and Glioblastoma attractors
Published 2025-02-01“…Dimensional reduction analysis of available data for white matter of the brain allows to locate the normal (homeostatic), Glioblastoma and Alzheimer's disease attractors in gene expression space and to identify paths related to transitions like carcinogenesis or Alzheimer's disease onset. A predefined path for aging is also apparent, which is consistent with the hypothesis of programmatic aging. …”
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129
Phototherapy in vitiligo
Published 2024-12-01“…The safety profile of phototherapy, including potential risks such as photodamage and carcinogenesis, is critically analyzed. The review underscores the importance of individualized treatment plans and ongoing research to optimize phototherapy protocols, ultimately aiming to improve the quality of life for vitiligo patients.…”
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130
Chemokines and Cytokines as Salivary Biomarkers for the Early Diagnosis of Oral Cancer
Published 2013-01-01“…Chemokines have been shown to be important in both inflammation and carcinogenesis and are able to be measured in saliva with relatively robust methods including enzyme-linked immunosorbent assays (ELISA). …”
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131
Emission Characteristics and Health Risk Assessment of Volatile Organic Compounds in Key Industries: A Case Study in the Central Plains of China
Published 2025-01-01“…The furniture manufacturing (4.55 × 10<sup>−3</sup>) and pharmaceutical (1.66 × 10<sup>−3</sup>) industries in organized emissions were at high risk of carcinogenesis, while the pharmaceutical industry in unorganized emissions (3.61 × 10<sup>−4</sup>) was at moderate risk of carcinogenesis. …”
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132
Hypoxia Induced Lnc191 Upregulation Dictates the Progression of Esophageal Squamous Cell Carcinoma by Activating GRP78/ERK Pathway
Published 2025-01-01“…Abstract Hypoxia is a typical hallmark of solid tumors and plays a crucial role in the progression of esophageal squamous cell carcinogenesis (ESCC). Nevertheless, the precise mechanisms underlying the involvement of hypoxia in tumor development remain unclear. …”
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133
A comprehensive analysis of the uterine microbiome in endometrial cancer patients - identification of Anaerococcus as a potential biomarker and carcinogenic cofactor
Published 2025-01-01“…The in vitro findings suggest its role in endometrial carcinogenesis, underscoring its potential as a target for future diagnostic and therapeutic applications.…”
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134
Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era
Published 2025-01-01“…Epigenetic alterations (such as hyper or hypo-methylation) play a meaningful role in esophageal carcinogenesis as well as the study of the tumor micro-environment, which has led to the development of novel immunological therapeutic options. …”
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135
Antioxidant Functions of the Aryl Hydrocarbon Receptor
Published 2016-01-01“…Increasing evidence points to a protective role of the AhR against carcinogenesis and oxidative stress. Herein, I will highlight data demonstrating a causal role of the AhR in the antioxidant response and present novel findings on potential AhR-mediated antioxidative mechanisms.…”
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136
Editorial: Current insights in Epigenetics and Epigenomics
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137
A Mathematical Model for DNA Damage and Repair
Published 2010-01-01“…In cells, DNA repair has to keep up with DNA damage to maintain the integrity of the genome and prevent mutagenesis and carcinogenesis. While the importance of both DNA damage and repair is clear, the impact of imbalances between both processes has not been studied. …”
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138
Exploring the Impact of Helicobacter pylori and Potential Gut Microbiome Modulation
Published 2023-01-01“…This review aims to discuss the role and effect of H. pylori in gastric carcinogenesis and gut microbiome modulation in eradicating H. pylori infection. …”
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139
Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
Published 2024-01-01“…EID assesses pathological changes to the normal composition and architecture of the skin that influence the flow of electrical current, including changes associated with inflammation, keratinocyte and melanocyte carcinogenesis, and scarring. Assessing the electrical properties of the skin across a range of frequencies and in multiple directions of current flow can provide diagnostic information to aid in the identification of pathologic skin conditions. …”
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140
Toll-Like Receptor 4 Activation in Cancer Progression and Therapy
Published 2011-01-01“…Further research of the role and mechanisms of TLR4 activation in cancer may provide novel antitumor vaccine adjuvants as well as TLR4 inhibitors that could prevent inflammation-induced carcinogenesis.…”
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