Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use by Yu Zhang, Ke Qiu, Jianjun Ren, Yu Zhao, Ping Cheng

“…Therefore, targeting human papillomaviruses and decoding molecular mechanisms by which human papillomaviruses drive carcinogenesis are of great necessity to better treat human papillomaviruses-related cancers. …”
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Changes in Lysine Methylation Contribute to the Cytotoxicity of Curcumin in Colon Cancer Cells by Roberta Santarelli, Paola Currà, Michele Di Crosta, Roberta Gonnella, Maria Saveria Gilardini Montani, Mara Cirone

“…Epigenetic abnormalities play a critical role in colon carcinogenesis, making them a promising target for therapeutic interventions. …”
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The role of PM2.5 exposure in lung cancer: mechanisms, genetic factors, and clinical implications by Chi-Yuan Chen, Kuo-Yen Huang, Chin-Chuan Chen, Ya-Hsuan Chang, Hsin-Jung Li, Tong-Hong Wang, Pan-Chyr Yang

“…This review summarizes the current understanding of how exposure to PM2.5 induces lung carcinogenesis and accelerates lung cancer development. …”
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Obesity, dietary interventions and microbiome alterations in the development and progression of prostate cancer by Shaun Trecarten, Michael A. Liss, Jill Hamilton-Reeves, John DiGiovanni

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Asbestos Induces Reduction of Tumor Immunity by Naoko Kumagai-Takei, Megumi Maeda, Ying Chen, Hidenori Matsuzaki, Suni Lee, Yasumitsu Nishimura, Junichi Hiratsuka, Takemi Otsuki

“…However, regarding bad prognosis of mesothelioma, medical approaches to ensure the recognition of the biological effects of asbestos and the pathological mechanisms of asbestos-induced carcinogenesis, as well as clinical trials to detect the early stage of mesothelioma, should result in better preventions and the cure of these malignancies. …”
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New insights into N6-methyladenosine in hepatocellular carcinoma immunotherapy by Mengran Li, Mengran Li, Hu Tian, Yanshuang Zhuang, Zili Zhang, Zili Zhang

“…In this study, we examine how m6A dysregulation affects hepatocellular carcinoma (HCC), with a particular emphasis on how it contributes to immunological evasion and carcinogenesis. We also investigate its potential as a novel therapeutic target, providing new perspectives on potential therapeutic approaches meant to enhance clinical results for patients with HCC.…”
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Integrative bioinformatics and immunohistochemical analysis unravel the prognostic significance and immunological implication of LIMCH1 in breast cancer: a retrospective study by Xin Yu, Bei Li, Wenge Li, Jingping Yuan, Shengrong Sun, Juanjuan Li

“…The functional annotations revealed pathways related to carcinogenesis and metabolic reconfiguration, thus suggesting the role of LIMCH1 in tumour progression. …”
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Neuroscience of cancer: unraveling the complex interplay between the nervous system, the tumor and the tumor immune microenvironment by Qibo Huang, Bai Hu, Ping Zhang, Ye Yuan, Shiwei Yue, Xiaoping Chen, Junnan Liang, Zhouping Tang, Bixiang Zhang

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A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets by Xinghao Fu, Feihong Ji, Qi He, Xinguang Qiu

“…In addition, the functional mechanism of YY1 also involves viral carcinogenesis and ribonucleic acid (RNA) metabolism related functions. …”
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Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma by Shu-Qin Jia, Jian-Jun Ren, Pei-De Dong, Xing-Kai Meng

“…Human hepatocellular carcinogenesis may be based on transformation of HPCs, not HSCs, through the formation of the transitional cells (hepatocyte-like cells and bile ductal cells).…”
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The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis by Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin, Jan A. Plock

“…However, it is pertinent and critical to question whether these cells could promote any residual tumor cells to proliferate, differentiate, or metastasize or even induce de novo carcinogenesis. Thus far, preclinical and clinical study findings are discordant. …”
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Prophylactic Role of Averrhoa carambola (Star Fruit) Extract against Chemically Induced Hepatocellular Carcinoma in Swiss Albino Mice by Ritu Singh, Jyoti Sharma, P. K. Goyal

“…These results demonstrate that ACE prevents the DENA/CCl4 induced adverse physical and biochemical alterations during hepatic carcinogenesis in mice. This study suggests the prophylactic role of Averrhoa carambola against hepatocellular carcinoma in mice; therefore, it could be employed for the further screening as a good chemopreventive natural supplement against cancer.…”
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Development and validation of a prognostic signature of breast cancer based on drug absorption, distribution, metabolism and excretion (ADME)-related genes by Zhixuan Wu, Yangyang Guo, Liangchen Qu, Xiaowu Wang, Hewei Zhang

“…Abstract The individual variation of carcinogenesis and drug response is influenced by the absorption, distribution, metabolism, and excretion (ADME) of drugs. …”
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ppENK Gene Methylation Status in the Development of Pancreatic Carcinoma by Lixin Yang, Hong Yang, Jingnan Li, Jianyu Hao, Jiaming Qian

“…Inhibition of ppENK expression by a change in its methylation status plays an important role in pancreatic carcinogenesis. ppENK methylation is thus an important molecular event that distinguishes pancreatic carcinoma tissue from normal pancreatic tissue. …”
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Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats by Yashiro Motooka, Hideaki Tanaka, Yuki Maeda, Misako Katabuchi, Tomoji Mashimo, Shinya Toyokuni

“…Exon 11 constitutes a region where pathogenic variants (PVs) accumulate, and mutations in this region are known to contribute to carcinogenesis. However, the impact of the heterozygous PVs of BRCA2 exon 11 on the life quality beyond cancer risk, including male fertility, remains unclear. …”
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POTENCY OF SOURSOP LEAF EXTRACT AND CURCUMIN WITH MAGNETIC AND MUCUS-PENETRATING NANOPARTICLE AS COLORECTAL CANCER ALTERNATIVE THERAPY by Faiza Rahma Ebnudesita, Ayik Rochyatul Jannah, Savira Butsainah Dienanta, Reny I'tishom

“…Curcumin also plays a role in the inhibition of nuclear factor κ-light-chain-enhancer of activated B (NF-κB) cells, thus inhibits carcinogenesis. For drug delivery, magnetic nanoparticles and mucus-penetrating nanoparticles could be used. …”
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Kidney and gallbladder stones and the risk of prostate cancer: Results from the EPICAP study. by Melissa Sawaya, Emilie Cordina-Duverger, Pierre-Jean Lamy, Brigitte Trétarre, Florence Menegaux

“…Chronic inflammation has emerged as a potential factor in prostate carcinogenesis. We investigated the role of kidney and gallbladder stones and the risk of prostate cancer.…”
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PSMA2 promotes chemo- and radioresistance of oral squamous cell carcinoma by modulating mitophagy pathway by Chun-I Wang, Cheng-Yi Chen, Ting-Wen Chen, Chun-Chia Cheng, Shu-Wen Hong, Tsung-You Tsai, Kai-Ping Chang

“…Furthermore, we confirmed that PSMA2 regulates cell cycle, mitochondrial dysfunction, and mitophagy, thereby contributing to carcinogenesis and resistance. Notably, mitophagy inducer exhibit antitumor effects in PSMA2-overexpressing OSCC xenograft mouse model. …”
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RNA binding protein ALYREF regulates ferroptosis to facilitate LUAD growth and metastasis via promoting SLC7A11 mRNA stability by Yanni Chen, Ting Zhao, Hao Chen, Jun Chen, Weili Han

“…Abstract Ferroptosis is of great significance in carcinogenesis as it interconnects with a multiplicity of biological processes. …”
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Antimutagenic Effect of Hibiscus sabdariffa L. Aqueous Extract on Rats Treated with Monosodium Glutamate by Ana Carla Guidini Valentini Gheller, Jacqueline Kerkhoff, Gerardo Magela Vieira Júnior, Kleber Eduardo de Campos, Marina Mariko Sugui

“…Under the conditions tested, H. sabdariffa L. presented a protective effect to CPA-induced damage to DNA of the treated animals, and it is a potential candidate as a chemopreventive agent against carcinogenesis.…”
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