Targeting compensatory proliferation signals in oral cancer by Loganathan Kavitha, Vijayashree Priyadharsini J, Anitha P, Paramasivam A

“…Apoptosis is an orchestrated phenomenon that regulates cell populations in physiological and pathological conditions. Carcinogenesis involves a state of disequilibrium between cell proliferation and cell death. …”
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Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions by Yuichiro Shimizu, Yasuhiro Uchimura, Naoshi Dohmae, Hisato Saitoh, Fumio Hanaoka, Kaoru Sugasawa

“…These results point to importance of physical interactions for stimulation of DNA glycosylases by XPC and have implications in the molecular mechanisms underlying mutagenesis and carcinogenesis in XP-C patients.…”
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Survival Analysis by Penalized Regression and Matrix Factorization by Yeuntyng Lai, Morihiro Hayashida, Tatsuya Akutsu

“…Furthermore, 80% of selected genes have been reported to correlate with carcinogenesis or lymphoma. Through NMF we found that DLBCL patients can be divided into 4 groups clearly, and it implies that DLBCL may have 4 subtypes which have a little different survival patterns. …”
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Standard: Human gastric organoids by Fan Hong, Ronghui Tan, Ting Wang, Nanshan Zhong, Hongling Zhao, Rui-hua Xu, Lin Shen, Yingbin Liu, Xuebiao Yao, Dongxi Xiang, Lijian Hui, Jianping Xiong, Dong Gao, Bing Zhao, Zhifeng Miao, Jie Hao, Yong Li, Shijun Hu, Boqiang Fu, Guoqiang Hua, Lei Wang, Zhao-Lei Zeng, Chong Chen, Jianmin Wu, Changlin Wang, Chunnian Wang, Xianbao Zhan, Chen Song, Chunping Yu, Yingying Yang, Gengming Niu, Yalong Wang, Tongbiao Zhao, Ye-Guang Chen

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Study of morphology with assessment of expression of proliferation marker Ki67 antigen and P53 protein in lesions of gall bladder by Ojasvi Ramesh, Mamta Gupta, Sanjay Kaushik, Seema Acharya, Brijesh Thakur, Aparna Bhardwaj

“…The results emphasize the potential of Ki-67 and p53 as biomarkers of carcinogenesis in gall bladder carcinoma.…”
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The Effect and Related Mechanism of Action of Astragalus Compatible with Curcumin against Colon Cancer Metastasis in Mice by Jiafei Wu, Decai Tang

“…Colon cancer (CC) is the third most common tumor worldwide. Colon carcinogenesis is strongly linked to inflammation. The initiation and progression of colon cancer may be influenced by epigenetic processes. …”
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Secretion of One Adipokine Nampt/Visfatin Suppresses the Inflammatory Stress-Induced NF-κB Activity and Affects Nampt-Dependent Cell Viability in Huh-7 Cells by Yi-Ching Lin, Hui-Chung Wu, Chen-Chung Liao, Yi-Chih Chou, Shwu-Fen Pan, Chi-Ming Chiu

“…However, its function in chronic inflammation and carcinogenesis in hepatocellular carcinoma (HCC) has not been well-defined. …”
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Differential Downregulation of E-Cadherin and Desmoglein by Epidermal Growth Factor by Miquella G. Chavez, Christian A. Buhr, Whitney K. Petrie, Angela Wandinger-Ness, Donna F. Kusewitt, Laurie G. Hudson

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Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice by Qin Chen, Krishna M. Sinha, Benoit de Crombrugghe, Ralf Krahe

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Implication of protein post translational modifications in gastric cancer by Houji Song, Mingze Zhang, Chengwang Guo, Xi Guo, Yuqi Ma, Yuntao Ma, Yuntao Ma

“…The diverse realm of PTM and PTM crosstalk is linked to many critical signaling events involved in neoplastic transformation, carcinogenesis and metastasis. This review provides a comprehensive overview of the impact of PTM on the occurrence and progression of GC. …”
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Differential Effects of Calorie Restriction and Exercise on the Adipose Transcriptome in Diet-Induced Obese Mice by Karrie E. Wheatley, Leticia M. Nogueira, Susan N. Perkins, Stephen D. Hursting

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Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

“…In this review, we aim to highlight the dual role of inflammasomes and proinflammatory cytokines during carcinogenesis paired with the distinguished effects of miRNAs upon inflammation cascades during tumor growth and progression.…”
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The study of the regulatory region of the Drosophila melanogaster Notch gene by new methods of directed genome editing by O. V. Andreyenkov, E. I. Volkova, N. G. Andreyenkova, S. A. Demakov

“…In humans, mutations in the Notch gene cause several hereditary diseases and carcinogenesis. Studies of the regulatory zone of the Notch gene in D. melanogaster have been conducted for several decades. …”
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Human TCR repertoire in cancer by Lin Chen, Yuan Hu, Bohao Zheng, Limei Luo, Zhenzhen Su

“…We explore the TCR repertoire in health and cancer, and discuss the implications of TCR repertoire analysis in understanding carcinogenesis, cancer progression, and treatment. Results The TCR repertoire analysis has enormous potential for monitoring the emergence and progression of malignancies, as well as assessing therapy response and prognosis. …”
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Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence by Patrycja Kozubek, Julia Kuźniar, Magdalena Czaja, Hanna Sitka, Urszula Kochman, Jerzy Leszek

“…They have been shown to affect carcinogenesis by modifying the expression of host genes through their functions as enhancers and promoters. …”
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Meta-Analysis and Systematic Review of the Role of Appendectomy in the Pathogenesis of Colorectal Cancer by M.I. A. Nezhad, N. P. Yabandeh

“…Given the potential for physiological alterations in the gastrointestinal tract following appendix removal, which may influence carcinogenesis, we embarked on a systematic review and meta-analysis to explore the possible association between appendectomy and the subsequent risk of colorectal cancer (CRC).Methods. …”
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Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells by Anda Huna, Kristine Salmina, Elina Jascenko, Gunars Duburs, Inna Inashkina, Jekaterina Erenpreisa

“…A positive link between DDR, self-renewal, and senescence signalling is initiated in the cells overcoming the tetraploidy barrier, indicating that cellular and molecular context of induced tetraploidy during this period of presenescence is favourable for carcinogenesis.…”
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Curcumin mimics of potential chemoprevention with NQO1 induction properties by Dalia R. Aboshouk, Ahmed R. Hamed, Siva S. Panda, Mohamed S. Bekheit, M. Adel Youssef, Adel S. Girgis

“…Abstract Chemoprevention is one of the accessible strategies for preventing, delaying or reversing cancer processing utilizing chemical intervention of carcinogenesis. NAD(P)H quinone oxidoreductase 1 (NQO1) is a xenobiotic metabolizing cytosolic enzyme/protein with important functional properties towards oxidation stress, supporting its ability in detoxification/chemoprotective role. …”
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Small Bowel Adenocarcinoma as the Cause of Gastrointestinal Bleeding in Celiac Disease: A Rare Malignancy in a Common Disease by Jaleh Fallah, Maxwell Eyram Afari, Alfredo C. Cordova, Adam J. Olszewski, Taro Minami

“…Small bowel carcinomas occurring in the context of celiac disease appear to be associated with higher rates of microsatellite instability than sporadic tumors, although other specific genomic abnormalities and mechanisms of carcinogenesis in celiac disease remain unknown. Conclusion. …”
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System Review about Function Role of ESCC Driver Gene KDM6A by Network Biology Approach by Jihua Ran, Hui Li, Huiwu Li

“…Fifty-five pathways are statistically involved in the network and most of them are functionally related to the processes of cell cycle, gene expression, and carcinogenesis. The biology themes of clusters 1, 2, and 3 are chromatin modification, regulation of gene expression by transcription factor complex, and control of cell cycle, respectively. …”
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