Radiation-Induced Peripheral Malignant Nerve Sheath Tumor Arising from Vestibular Schwannoma after Linac-Based Stereotactic Radiation Therapy: A Case Report and Review of Literatur... by Putipun Puataweepong, Taweesak Janwityanujit, Noppadol Larbcharoensub, Mantana Dhanachai

“…Regarding the uncertainty of carcinogenesis risk, we should still practice radiation therapy with caution, especially in the young patient with tumor predisposition syndrome. …”
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PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis by Lina Sabatino, Alessandra Fucci, Massimo Pancione, Vittorio Colantuoni

“…Its function in colon carcinogenesis has largely been debated; accumulating evidence, however, supports a role as tumor suppressor through modulation of crucial pathways in cell differentiation, apoptosis, and metastatic dissemination. …”
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Multiple Factors Determine the Oncolytic or Carcinogenic Effects of TLRs Activation in Cancer by Yingxiang Yang, Chengyue Jin, Anthony Yeo, Bo Jin

“…However, chronic inflammation is also involved in carcinogenesis. Activation of NF-ĸB inhibits apoptosis and under certain circumstances, tumor cell survival. …”
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C-Reactive Protein and Breast Cancer: New Insights from Old Molecule by Shilpa Balaji Asegaonkar, Balaji Narayanrao Asegaonkar, Unmesh Vidyadhar Takalkar, Suresh Advani, Anand Pandurang Thorat

“…Chronic inflammation is a key contributor in the development and progression of carcinogenesis. Inflammatory pathways play an important role in the causation of breast cancer. …”
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The Role of the Pathoanatomical Diagnosis «Chronic Gastritis» in the System of Personified Cancer Prevention by A. V. Kononov

“…Molecular classification of gastric cancer is considered from the standpoint of carcinogenesis cascade and WHO 2010 histological classification. …”
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Dysplasia in Inflammatory Bowel Diseases: Definition and Clinical Impact by Karel Geboes, Paul Rutgeerts

“…Additional techniques to search for genetic defects associated with carcinogenesis can help to support the diagnosis. They can identify changes in DNA content and molecular changes resulting from defects of genes controlling cell proliferation and death or tissue structure. …”
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Altered Peroxisome-Proliferator Activated Receptors Expression in Human Endometrial Cancer by Paweł Knapp, Adrian Chabowski, Agnieszka Błachnio-Zabielska, Katarzyna Jarząbek, Sławomir Wołczyński

“…Peroxisome proliferator-activated receptors (PPARs) belong to a family of nuclear hormone receptors acting as transcriptional factors, recently involved also in carcinogenesis. Present study was undertaken to evaluate the presence and subcellular localization of different PPAR isoforms (α, β, γ) in healthy endometrial tissue (n=10) and endometrial carcinoma (FIGO I, endometrioides type, G1, n=35). …”
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PTEN Gene: A Model for Genetic Diseases in Dermatology by Corrado Romano, Carmelo Schepis

“…The involvement of PTEN function in melanoma and multistage skin carcinogenesis, with its implication in cancer treatment, and the role of front office in diagnosing PHTS are the main reasons why the dermatologist should know about PTEN.…”
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Prognostic significance of ımmunhistochemical axl expression in pancreas ductal adenocarcinomas by Ozden Oz, Asuman Argon, Tulu Ayata Kebat, Ozlem Ozdemir, Savas Yakan

“…Conclusion: It was found that increased expression of Axl, which is known to increase EMT-mediated metastasis in carcinogenesis, may be an indicator of local spread and poor prognosis in PDAC patients. …”
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Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle by N. Torkamani, N. W. Rufaut, L. Jones, R. Sinclair

“…This new view provides insights into epidermal control and the possible involvement of epidermal stem cells in nonmelanoma skin carcinogenesis.…”
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The Role of PPARs in Placental Immunology: A Systematic Review of the Literature by Stefan Hutter, Julia Knabl, Ulrich Andergassen, Udo Jeschke

“…They are expressed in most human organs and their function extends from regulating metabolism, homeostasis, and carcinogenesis to immune response. In the recent years, PPARs have been identified in most reproductive tissues and in all lines of immune cells. …”
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Development of a new HPLC method for wogonin in rat plasma: Compatibility of standard and test samples by Salmani Jumah Masoud Mohammad, Wu Xue, Jacob Joe Antony, Fu Rong, Chen Baoan

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A First Report of Synchronous Intracapsular and Extracapsular Hepatic Adenoma by Murat Derebey, Ilhan Karabicak, Savas Yuruker, Gokhan Lap, Bilge Can Meydan, Murat Danaci, Kagan Karabulut, Necati Ozen

“…Ectopic liver in the gallbladder can undergo fatty change, hemosiderosis, cholestasis, cirrhosis, hemangioma, focal nodular hyperplasia, adenoma, and even carcinogenesis. The incidence of extracapsular hepatic adenoma is not known, but only two cases have been reported. …”
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A Perspective on Withania somnifera Modulating Antitumor Immunity in Targeting Prostate Cancer by Seema Dubey, Manohar Singh, Ariel Nelson, Dev Karan

“…The bioactive compounds in these supplements may serve as chemotherapeutic substances competent to inhibit or reverse the process of carcinogenesis. The role of WFA is appreciated to polarize tumor-suppressive Th1-type immune response inducing natural killer cell activity and may provide an opportunity to manipulate the tumor microenvironment at an early stage to inhibit tumor progression. …”
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Expression of Semaphorin 3F and Its Receptors in Epithelial Ovarian Cancer, Fallopian Tubes, and Secondary Müllerian Tissues by Christina D. Drenberg, Sandra Livingston, Ren Chen, Patricia A. Kruk, Santo V. Nicosia

“…While semaphorins and their receptors appear to play a role in tumor carcinogenesis, little is known about the role of semaphorin 3F (S3F) in epithelial ovarian cancer (EOC) development. …”
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Antitumoral and Anti-inflammatory Roles of Somatostatin and Its Analogs in Hepatocellular Carcinoma by Argyrios Periferakis, Georgios Tsigas, Aristodemos-Theodoros Periferakis, Ioana Anca Badarau, Andreea-Elena Scheau, Mircea Tampa, Simona Roxana Georgescu, Andreea Cristiana Didilescu, Cristian Scheau, Constantin Caruntu

“…The complexity of the treatment is also justified by the unique pathogenesis of HCC that involves intricate processes such as chronic inflammation, fibrosis, and multiple molecular carcinogenesis events. During the last three decades, multiple in vivo and in vitro experiments have used somatostatin and its analogs (SSAs) to reduce the proliferative and metastatic potential of hepatoma cells by inducing their apoptosis and reducing angiogenesis and the inflammatory component of HCC. …”
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Development of animal models to study aggressive thyroid cancers by Shovan Dutta, Jeffrey A Knauf

“…The earliest mouse models of thyroid cancer relied on hormone, radiation or chemical carcinogenesis to induce tumors. However, as our understanding of the genetic alterations driving thyroid cancer has expanded, more sophisticated genetic engineering techniques have been employed to create models with thyroid-specific expression of these driver mutations. …”
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PMEPA1 Serves as a Prognostic Biomarker and Correlates with Immune Infiltrates in Cervical Cancer by Jing Li, Wei-min Kong

“…Emerging studies have demonstrated that Prostate transmembrane protein androgen induced 1 (PMEPA1) plays crucial roles in the carcinogenesis of many developing human tumors. However, the clinical significance of PMEPA1 expression in cervical cancer (CC) and its contribution to cancer immunity have not been investigated. …”
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Immunostaining of Lgr5, an Intestinal Stem Cell Marker, in Normal and Premalignant Human Gastrointestinal Tissue by Laren Becker, Qin Huang, Hiroshi Mashimo

“…Our findings suggest that (1) Lgr5 is a potential marker of intestinal stem cells in humans and (2) loss of restriction to the stem cell niche is an early event in the premalignant transformation of stem cells and may play a role in carcinogenesis.…”
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Landscape Of HOXA Genes Methylation in Colorectal Cancer by Muhiddin Ishak, Rashidah Baharudin, Loh Teng-Hern Tan, Learn-Han Lee, Nurul-Syakima Ab Mutalib

“…Dysregulated HOXA expression influences various aspects of carcinogenesis processes. Therefore, this study aims to elucidate the methylation landscape of HOXA genes in CRC. …”
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