Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference by Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva

“…ASOs are also being studied worldwide as unique candidates for developing therapies for N-of-1 therapies. …”
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Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics by Xiaoqing Wu, Wenping Lu, Chaojie Xu, Cuihong Jiang, Zhili Zhuo, Ruipeng Wang, Dongni Zhang, Yongjia Cui, Lei Chang, Xi Zuo, Ya’nan Wang, Heting Mei, Weixuan Zhang, Mengfan Zhang, Chen Li

“…A total of 993 intersecting genes were identified as candidates for further survival analysis. Further analysis revealed that CD80 expression was positively correlated with the survival of HGSOC patients. …”
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Prevalence and associated factors of postpartum anemia after cesarean delivery in public hospitals of Awi zone, North West Ethiopia, 2023; a cross-sectional study. by Gebretsadek Habtamu, Asmare Talie, Tinsae Kassa, Dawit Misganaw Belay

“…Variables with a p-value of 0.25 or less in bivariable analysis were candidates for multivariable analysis and P-value < 0.05 in multivariable analysis was considered to declare a result as statistically significant in this study.…”
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A measure of the difference between test sets for generating controlled random tests by V. N. Yarmolik, V. V. Petrovskaya, I. Mrozek

“…It is shown that test sets, which are indistinguishable when Hamming distance is used as a measure of difference, have different values of AD(Ti, Tk) that allows to make more accurate classification of randomly generated sets as candidates for test sets.…”
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Optimizing the selection of quantitative traits in plant breeding using simulation by Rafael Augusto Vieira, Ana Paula Oliveira Nogueira, Roberto Fritsche-Neto

“…Updates including top-performing candidates, but conserving variability enhances gains and accuracy. …”
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Performance of an Electronic Health Record–Based Automated Pulmonary Embolism Severity Index Score Calculator: Cohort Study in the Emergency Department by Elizabeth Joyce, James McMullen, Xiaowen Kong, Connor O'Hare, Valerie Gavrila, Anthony Cuttitta, Geoffrey D Barnes, Colin F Greineder

“…The clinical decision support should facilitate real-time identification of patients who may be candidates for outpatient PE management.…”
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Comparative transcriptomics analysis of Zygosaccharomyces mellis under high-glucose stress by Gongliang Liu, Xinyu Bi, Changli Tao, Yongtao Fei, Sujuan Gao, Jinglong Liang, Weidong Bai

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Individual profiles of psychological suitability for police service (according to the results of the individual typological questionnaire) by V. I. Barko, V. V. Barko, O. O. Yevdokimova

“…These typical psychological profiles include fifteen variants, the study of which will help the psychologists of the National Police psychological support units to formulate scientifically sound forecasts of the success of the candidates for police officers during the psychological stage of professional selection, as well as to help police officers in conducting competitions for vacant positions, carrying out the certification procedure, etc. …”
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Biomarkers to predict the outcomes of surgical intervention for aortic dissection by Abanob G. Hanna, Fabian Jimenez Contreras, Omar M. Sharaf, Griffin P. Stinson, Philip J. Hess

“…The aim of this review is to summarize the literature concerning the prognostic ability of various preoperative biomarkers for patients undergoing surgical repair of the thoracic and abdominal aorta to elucidate whether these biomarkers could improve the selection of surgical candidates. Methods Relevant biomarkers were selected if they had predictive value in inflammatory disease processes and/or cardiovascular disease. …”
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Evaluation of Antimicrobial Activity of Conyza bonariensis Leaf Extracts against Clinically Isolated Fungi Causing Superficial Infection by Yidnekachew Girma, Tamene Milkessa Jiru

“…Further studies should consider this plant as one of the best candidates for the discovery of potent antimicrobial compounds that treat superficial infections.…”
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Sybil-Resistant Self-Sovereign Identity Utilizing Attested Execution Secure Processors and Zero-Knowledge Membership Proofs by Koichi Moriyama, Akira Otsuka

“…SSI brings various benefits to natural persons, such as owning controls; conversely, digital identity systems in the real world require Sybil-resistance to comply with anti-money laundering (AML) and other needs. CanDID by Maram et al. proposed that decentralized digital identity systems may achieve Sybil-resistance and preserve privacy by utilizing multi-party computation (MPC), assuming a distributed committee of trusted nodes. …”
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The impact of insurance type on listing status and wait‐list mortality of patients with left ventricular assist devices as bridge to transplantation by Alexandros Briasoulis, Emmanuel Akintoye, Chakradhari Inampudi, Aziz Hammoud, Paulino Alvarez

“…Abstract Aims Adequate health insurance coverage is necessary for heart transplantation (HT) candidates. Prior studies have suggested inferior outcomes post HT with public health insurance. …”
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Women’s mental health in the doctoral context: Protective function of the psychological capital and academic motivation by Angel Deroncele-Acosta, Roger Pedro Norabuena-Figueroa, Emerson Damian Norabuena-Figueroa

“…Background: Science recognizes the anxieties, depression, stress, and “turbulences” that women face in doctoral studies, but women’s mental health in this context is still little addressed, even though it is a critical aspect for the well-being, persistence, and success of women doctoral candidates, who continue to be underrepresented in many professional fields. …”
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The Effectiveness of Varying Combination Ratios of A. cordifolia and M. indica against Field and Laboratory Strains of P. falciparum In Vitro by Yakubu Jibira, Elizabeth Cudjoe, Frederick M. Tei-Maya, Benjamin Ayensu, Linda E. Amoah

“…There is therefore an urgent need to identify new drug candidates that will be effective against the existing malaria parasites. …”
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Assessment of Genetic Parameters for Vitamin A, Vitamin C, and TSS Content Results in Melon Line Crosses at Five Maturity Stages by Achmad Amzeri, Kaswan Badami, Amin Zuhri, Gita Pawana, Suhartono Suhartono, Syaiful Khoiri, Ahmad Syaiful Umam, Yudi Asmoro, Siti Rohmatin, Halimatus Sa’diyah, Badriyah Badriyah

“…The assessment of hybrid melon candidates on important characteristics (vitamin A, vitamin C, and TSS) at five maturity stages is needed to get hybrid melon varieties with good fruit quality and determine the right harvest time. …”
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Genome sequence and evaluation of safety and probiotic potential of Lacticaseibacillus paracasei LC86 and Lacticaseibacillus casei LC89 by Ting Chen, Yunjiao Zhao, Yunjiao Zhao, Yixuan Fan, Yao Dong, Zhonghui Gai

“…The oral LD50 for both LC86 and LC89 in mice was &gt;2 × 1010 CFU/kg.ConclusionThe experimental results above demonstrated the probiotic characteristics and safety of LC86 and LC89, indicating their potential as candidates for probiotics for human and animal applications.…”
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Effects of different doses of skt-b vibrio probiotic bacteria addition on survival and growth rate of tiger shrimp (Penaeus monodon) larva by . Widanarni, M.A. Lidaenni, Dinamella Wahjuningrum

“…Vibrio SKT-b is one of the probiotic bacteria candidates that could suppressed the growth of pathogenic bacteria Vibrio harveyi and could increase survival rate of tiger shrimp larva. …”
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Matching-Adjusted Indirect Comparison of the Efficacy at Week 32 of Tralokinumab and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis by Tiago Torres, Anne Sohrt Petersen, Ulla Ivens, Albert Bosch Vilaro, John Stinson, José Manuel Carrascosa

“…Abstract Introduction Tralokinumab and dupilumab are biological agents licensed for the treatment of moderate-to-severe atopic dermatitis (AD) in adult patients who are candidates for systemic treatment. However, no head-to-head studies of their efficacy have been conducted. …”
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Stem Cell Therapy: A Compassionate Use Program in Perianal Fistula by M. D. Herreros, D. Garcia-Olmo, H. Guadalajara, T. Georgiev-Hristov, L. Brandariz, M. Garcia-Arranz

“…Under controlled circumstances and approved by European and Spanish laws, a compassionate use program allows the use of stem cell therapy for patients with nonhealing diseases, mostly complex fistula-in-ano, who do not meet criteria to be included in a clinical trial. Candidates had previously undergone multiple surgical interventions that had failed. …”
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Sixth-Month Perinatal Outcomes of Anemic Pregnancies by Emel Kıyak Çağlayan, Öznur Küçük, Ayşe Yeşim Göçmen, Levent Seçkin, Ayla Aktulay, Yaprak Engin Üstün

“…Therefore maternal candidates with high rates of anemia such as housewives should be closely monitored during pregnancy and in the postpartum period for fetal development. …”
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