Data-driven exploration of weak coordination microenvironment in solid-state electrolyte for safe and energy-dense batteries by Zhoujie Lao, Kehao Tao, Xiao Xiao, Haotian Qu, Xinru Wu, Zhiyuan Han, Runhua Gao, Jian Wang, Xian Wu, An Chen, Lei Shi, Chengshuai Chang, Yanze Song, Xiangyu Wang, Jinjin Li, Yanfei Zhu, Guangmin Zhou

“…Assisting with unsupervised learning, we use Climbing Image-Nudged Elastic Band simulations to screen lithium-ion conductors and screen out five potential candidates that elucidate the impact of lithium coordination environment on conduction behavior. …”
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Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment by Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon

“…Conversely, cellular responses to E6 and E7 were limited in quantity and cytotoxic capacity, and tumor E6 and E7 expression persisted.Conclusions These data highlight antigenicity beyond HPV16 E6 and E7 and nominate candidates for antigen-directed therapies.…”
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Nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging by Jin Yao, Yubin Fan, Yunhui Gao, Rong Lin, Zhihui Wang, Mu Ku Chen, Shumin Xiao, Din Ping Tsai

“…Multiplexing meta-lenses present promising candidates for achieving this functionality. However, current multiplexing meta-lenses lack spectral modulation, and crosstalk between different wavelengths hampers the imaging quality, especially for biological samples requiring precise wavelength specificity. …”
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Synthesis and optical properties of LaSrGaO4:RE3+ (RE = Sm, Eu, Ho) single crystals via optical float zone method by Hasan Yilmaz, Masahiko Isobe, Oliver Clemens, Markus Suta, Pascal Puphal

“…Together with a high physical density of ∼6.4 g/cm3, these phosphors could be conceptualized as interesting candidates for X-ray imaging phosphors aiming at high light yields.…”
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Pseudomonas azotoformans and Pseudomonas putida: Novel kiwifruit-native biological control agents against Pseudomonas syringae pv. actinidiae by Cristiana Correia, Antonio Cellini, Irene Donati, Panagiotis Voulgaris, Adebayo Ebenezer Obafemi, Elia Soriato, Elodie Vandelle, Conceição Santos, Francesco Spinelli

“…Overall, these results open new perspectives to develop commercial products for Psa management based on kiwifruit-native bacteria, well-adapted to common orchard management practices, with a high efficiency of host plant colonization, at Psa-conducive temperatures, and point out possible mechanisms of action for these two BCA candidates, supporting further steps to assess their effectiveness in orchard conditions.…”
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Development of new powdery mildew resistant lines in garden pea (Pisum sativum L.) using induced mutagenesis and validation of resistance for the er1 and er2 gene through molecular... by Akhilesh Sharma, Devinder Kumar Banyal, Vinod Janardan Dhole, Bansuli, Ranbir Singh Rana, Rajesh Kumar, Prabhat Kumar, Nimit Kumar, Srishti, Arshia Prashar, Vivek Singh, Anoushka Sharma

“…These PM-resistant mutants can be promising candidates as the new source of resistance for future pea breeding programs.…”
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Improving the Determination of Supernova Cosmological Redshifts by Using Galaxy Groups by Erik R. Peterson, Bastien Carreres, Anthony Carr, Daniel Scolnic, Ava Bailey, Tamara M. Davis, Dillon Brout, Cullan Howlett, David O. Jones, Adam G. Riess, Khaled Said, Georgie Taylor

“…We find that 91% of these candidates can be associated with groups, consistent with predictions from simulations given the sample size. …”
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Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action by Aurangzeb Sana, Aurongzeb Muhammad, Shamim Shahbaz, Rashid Yasmeen, Khan Khalid Mohammed, Aziz Tariq, Alharbi Metab, Alasmari Abdullah F.

“…The objective of this research was to identify certain promising drug candidates that could excessively stimulate the HslV protease, leading to uncontrolled protein breakdown in the pathogens. …”
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Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection by Thi Hao Vu, Chaeeun Kim, Anh Duc Truong, Jun-Mo Kim, Hyun S. Lillehoj, Yeong Ho Hong

“…Overall, our study provides insights into the role of lncRNAs in the host's response to HPAIV H5N1 infection in chickens and highlights potential candidates for further investigation into host–pathogen interactions. …”
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Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

“…In conclusion, this detailed landscape provides a rich resource to identify target candidates and therapeutic vulnerabilities within and across species and supports feline FSA as relevant models for the human disease.…”
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Sentinel-1-Aided Mutual Calibration of TanDEM-X DEMs for the Estimation of Height and Volume Changes by Carolina Gonzalez, Luca Dell'Amore, Jose-Luis Bueso-Bello, Pietro Milillo, Gabriele Schwaizer, Thomas Nagler, Paola Rizzoli

“…In this article, we present a novel technique for performing an automatic selection of reliable natural tie-points from Sentinel-1 repeat-pass time-series, by exploiting persistent scatterers candidates, and we discuss their applicability to TanDEM-X data. …”
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Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-indu... by Peixin Liu, Xiaodong Liu, Zihao Wu, Kui Shen, Zhaofeng Li, Xiaowei Li, Qifeng Wu, Leung Chan, Zhong Zhang, Yutong Wu, Liwen Liu, Tianfeng Chen, Yi Qin

“…These findings suggest that LNT-UsSeNPs are promising candidates for further development in nanomedicine for the effective treatment of SCI. …”
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Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…In conclusion, integrated multi-omics analysis can be useful for elucidating the various characteristics of new drug candidates in early phase clinical trials.…”
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Adaptive Cut Selection in Mixed-Integer Linear Programming by Turner, Mark, Koch, Thorsten, Serrano, Felipe, Winkler, Michael

“…These solvers have millions of parameter combinations, and so are excellent candidates for parameter tuning. Cut selection scoring rules are usually weighted sums of different measurements, where the weights are parameters. …”
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Heterogeneous graph convolutional neural network for protein-ligand scoring by Kevin Crampon, Alexis Giorkallos, Xavier Vigouroux, Stephanie Baud, Luiz Angelo Steffenel

“…Computational simulations like molecular docking enable fast exploration of large databases of compounds and extract the most promising molecule candidates for further in vitro and in vivo tests. Structure-based molecular docking is a complex process mixing both surface exploration and energy estimation to find the minimal free energy of binding corresponding to the best interaction location. …”
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Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy by Hemanathan Vembuli, Sheeja Rajasingh, Patrick Nabholz, Jefferson Guenther, Brian R. Morrow, Margaret M. Taylor, Marziyeh Aghazadeh, Vinoth Sigamani, Johnson Rajasingh, Johnson Rajasingh, Johnson Rajasingh

“…Given their promising characteristics compared to traditional MSCs, PDLF-derived iMSCs are strong candidates for future clinical studies in bone regeneration and other regenerative dental therapies.…”
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The search for microRNAs potentially involved in the selfrenewal maintaining of laboratory rat pluripotent stem cells by V. V. Sherstyuk, S. P. Medvedev, M. T. Ri, Y. V. Vyatkin, O. V. Saik, D. N. Shtokalo, S. M. Zakian

“…The use of bioinformatic and systems biology approaches is the first step, which is necessary for choosing candidates for the subsequent experimental studies. …”
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Editorial by Ann-Kristin Kölln, Antony Mason, Maria Lenk, Jörg Tremmel, Markus Rutsche

“…After all, political parties act as gatekeepers because they are in control of the list of candidates running for election. Drawing on theories of party politics, the authors argue for five different factors that could possibly explain the share of young MPs: the age of the party leader, the age of the party, the size of party support, the party’s ideology, and the party’s formal recruitment procedure for candidates. …”
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Improving vaccination uptake in pediatric Cochlear implant recipients by Lisa Jin, Paula Téllez, Ruth Chia, Daphne Lu, Neil K. Chadha, Julie Pauwels, Simon Dobson, Hazim Al Eid, Frederick K. Kozak

“…Pneumovax-23, a vaccine for high-risk patients (such as cochlear implant candidates) was missed in all cases. Conclusion Pre-operative vaccination for cochlear implant recipients improved dramatically with the addition of a vaccine specialist. …”
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Enhanced biocidal efficacy of alcohol based disinfectants with salt additives by Euna Oh, Hyerin Shin, Sumin Han, Soo Jee Do, Younseo Shin, Ji Hee Pi, Youngjin Kim, Dae-Hong Ko, Kyu Hyoung Lee, Hyo-Jick Choi

“…Overall, the inclusion of salt in alcohol solutions significantly enhanced their disinfection activities, positioning these solutions as promising candidates for long-term disinfection and maintenance of hygienic environments. …”
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