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2881
Advances in antiviral strategies targeting mosquito-borne viruses: cellular, viral, and immune-related approaches
Published 2025-02-01“…Additionally, it explores immunomodulatory therapies to enhance antiviral responses and emphasizes the potential of drug repurposing, bioinformatics, artificial intelligence, and deep learning in identifying novel antiviral candidates. Continued research is crucial in mitigating MBVs’ impact and preventing future outbreaks.…”
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2882
Mentoring in education: an analysis of international practices and their implementation in Russia
Published 2024-05-01“…During this probation period, candidates are required to work for one year in a school as a trainee teacher under the guidance of mentor teachers. …”
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2883
The Potential of Menstrual Blood-Derived Mesenchymal Stem Cells for Cartilage Repair and Regeneration: Novel Aspects
Published 2018-01-01“…MSCs seem promising candidates for cartilage regeneration; however, no clinically effective stem cell-based repair method has yet emerged. …”
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2884
Genomic Analysis of miR-21-3p and Expression Pattern with Target Gene in Olive Flounder
Published 2017-09-01“…Taken together, this current study contributes to infer the target gene candidates for the miR-21-3p using bioinformatics tools. …”
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2885
XVII. Yüzyılda Osmanlı Hac Menzilleri: Rûznâmçeci İbrahim Efendi Kethüdâsı Hacı Ali Bey’in Tuhfetü’l-Huccâc Risâlesi Örneği
Published 2020-06-01“…It was connected to Istanbul and the Balkans through Adana-Konya-Akşehir and Iznik in the west direction. Pilgrim candidates coming from these main roads and other secondary roads connecting Anatolia from north to south and east to west would join in Damascus and set out to go to Hejaz with the pilgrimage caravan created there. …”
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2886
Occurrence of Fatal and Nonfatal Adverse Outcomes after Heart Transplantation in Patients with Pretransplant Noncytotoxic HLA Antibodies
Published 2013-01-01“…HLA antibodies (HLA ab) in transplant candidates have been associated with poor outcome. However, clinical relevance of noncytotoxic antibodies after heart transplant (HT) is controversial. …”
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2887
Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers
Published 2025-02-01“…The aim of this study was to identify additional ncRNA candidates that are implicated in obesity, elucidating their potential as key regulators of the pathogenesis of obesity.MethodsWe identified distinct ncRNA expression profiles in omental adipose tissue in obese and healthy subjects through comprehensive whole-transcriptome sequencing. …”
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2888
Development of Scalable Elastic Gelatin Hydrogel Films Crosslinked with Waterborne Polyurethane for Enhanced Mechanical Properties and Strain Recovery
Published 2025-01-01“…The results indicate a notable enhancement in the mechanical properties and biocompatibility of gelatin hydrogels upon the introduction of WPU, positioning these films as superior candidates for biomedical applications such as tissue engineering and wound dressing.…”
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2889
Association of Glioblastoma Multiforme Stem Cell Characteristics, Differentiation, and Microglia Marker Genes with Patient Survival
Published 2018-01-01“…This raises concerns regarding the suitability of the other target structures as prognostic markers, but makes both CD133 and Nestin candidates for GBM therapy. Nevertheless, a search for more specific marker proteins is urgently needed.…”
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2890
Dynamic Response of Graphitic Targets with Tantalum Cores Impacted by Pulsed 440-GeV Proton Beams
Published 2021-01-01“…The study comprises different graphite grades, such as polycrystalline, expanded and carbon-fiber reinforced graphite, and low-density graphitic foams, all candidates for beam-intercepting devices in high-power accelerators. …”
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2891
USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer
Published 2025-02-01“…Our subsequent goal was to identify potential genes associated with the autophagy panel and assess their prognostic significance, biological roles, and mechanisms in CRC metastasis. Among the candidates, CENPF emerged as the top gene in our screening process. …”
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2892
Comparison of Intranasal Outer Membrane Vesicles with Cholera Toxin and Injected MF59C.1 as Adjuvants for Malaria Transmission Blocking Antigens AnAPN1 and Pfs48/45
Published 2016-01-01“…Bacterial outer membrane vesicles (OMV) are attractive candidates potentially combining antigenic and adjuvant properties in one substance. …”
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2893
Physics-Based Self-Supervised Grasp Pose Detection
Published 2024-12-01“…Given a gripper-object pair, it samples grasping pose candidates using a modified version of GPD (implementing inner-grasps, CAD support…) and quantifies their quality using the MuJoCo physics engine and a grasp quality metric that takes into account the pose of the object over time. …”
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2894
Proteome-Wide Identification and Comparison of Drug Pockets for Discovering New Drug Indications and Side Effects
Published 2025-01-01“…In addition, 62,077 significant matches were found between druggable pockets and 1872 known drug pockets, highlighting candidates for drug repositioning. We repositioned progesterone to ADGRD1 for pemphigus and breast cancer, as well as estradiol to ANO2 for shingles and medulloblastoma, which were validated via molecular docking. …”
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2895
Dual‐Enhanced SERS Satellite Immuno‐Nanocomplex for Multiple PSA‐Mediated PHI Assay Toward Clinical Prostate Cancer Screening
Published 2025-02-01“…Practical analysis of clinical samples demonstrated the SERS immunoassay is capable of identifying the PCa subjects from healthy candidates (N = 13), and monitoring PCa patients before and after surgery (N = 5), as well as screening suspicious ones who are in the “gray zone” (N = 10). …”
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2896
3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications
Published 2021-01-01“…Thus, they have been demonstrated to be good candidates for in vivo repair of different tissues. …”
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2897
High Energy Density Welding of Ni-Based Superalloys: An Overview
Published 2025-01-01“…The use of these welding technologies can be decisive in the employment of sophisticated alloys such as Ni-based superalloys, which are notoriously excellent candidates for industrial components subjected to high temperatures and corrosive work conditions. …”
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2898
4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies
Published 2025-01-01“…The results of the docking studies were consistent with the in-vitro experiments and identified (9) and (14) as the candidates with the highest affinity towards MARK4. …”
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2899
Discovering Large-scale Structure at 2 < z < 5 in the C3VO Survey
Published 2025-01-01“…In the C3VO fields, we were able to recover many of the previously known structures in the literature as well as find hundreds of new overdensity candidates, once again demonstrating the powerful capabilities of VMC mapping when applied to wide-field optical and infrared galaxy evolution surveys at ever higher redshifts.…”
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2900
Thermo-elastic topology optimization and experimental characterization for multiphase structure with high thermal stiffness invariability
Published 2025-02-01“…First, a series of quasi-static characterization tests under different temperatures was performed to assess the thermo-elastic properties of the multiphase material candidates. Second, an HTSI design method was proposed based on the multiphase material properties and DMO for acquiring both 2D and 3D multiphase structures. …”
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