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16241
Muscle contractile properties and perceived fatigue in the general and diseased population
Published 2024-12-01“…We pooled data on perceived fatigue, physical fitness, and contractile properties from six studies, including a control group (n = 90), cancer survivors (n = 27), patients with chronic obstructive pulmonary disease (COPD; n = 16), chronic myeloid leukemia (CML; n = 20), and statin users (n = 64). …”
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16242
One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction
Published 2025-01-01“…Among these, Cu _2 S and CuS quantum dots have demonstrated notable photothermal effects and antibacterial activity, making them promising candidates for various biomedical applications, including cancer treatment. This study focuses on the synthesis of CuS and Cu _2 S quantum dots functionalized with bovine serum albumin (BSA), marking an important step toward their potential biomedical use. …”
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16243
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice
Published 2025-01-01“…Abstract Chemotherapeutic therapies for cancer are frequently associated with cytotoxic side effects that can be harmful to human health, including the development of intestinal mucositis (IM). …”
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16244
Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats
Published 2019-01-01“…In addition, a downregulation of P-glycoprotein (P-gp) and breast cancer resistance protein was found in the brain. …”
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16245
Sources and Health Risks of PM2.5-bound PAHs in a Small City along with the “Clean Heating” Policy
Published 2022-06-01“…Furthermore, the incremental lifetime cancer risks (ILCR) and BaP equivalent concentrations (BaPeq) increased in the HS. …”
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16246
Comparative Structural and Biophysical Investigation of <i>Lycosa erythrognatha</i> Toxin I (LyeTx I) and Its Analog LyeTx I-b
Published 2025-01-01“…<b>Conclusions</b>: Our findings provide insights into the structural and functional modifications that enhance the antimicrobial and therapeutic potential of LyeTx I-b, offering valuable guidance for the design of novel peptides targeting resistant bacterial infections and cancer.…”
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16247
Analysis of mutations in CDC27, CTBP2, HYDIN and KMT5A genes in carotid paragangliomas
Published 2018-09-01“…Thus, there is a necessity to improve the methods for identification of cancer-asso ciated genes as well as pathogenic mutations.…”
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16248
High levels of soluble P-selectin, neutrophil extracellular traps, and myeloperoxidase as risk factor of deep vein thrombosis in malignancy patients receiving platinum-based chemot...
Published 2024-04-01“…VTE events increase the mortality rate of patients with cancer receiving platinum-based chemotherapy. Soluble P-Selectin, Neutrophil Extracellular Traps (NET), and myeloperoxidase (MPO) are risk factors associated with DVT in malignancy patients receiving platinum-based chemotherapy. …”
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16249
Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics
Published 2024-12-01“…ObjectiveThis study aimed to explore the clinical relevance of Human Epidermal Growth Factor Receptor 2 (HER2) in urothelial carcinoma (UC) and its association with glycolytic metabolic markers, insulin resistance, and beta-cell function, shedding light on potential therapies targeting both HER2 pathways and cancer metabolism.MethodsIn this retrospective analysis, 237 UC patients from the Departments of Urology and Pathology at Shandong Provincial Hospital were examined. …”
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16250
A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
Published 2025-01-01“…Over 90% of the global population is chronically infected with EBV, impacting numerous cancer-related cases annually. However, none of the effective prophylactic vaccines against EBV is approved at present.MethodsIn this study, we developed a novel vaccine candidate based on epitope peptides from the receptor-binding domain of EBV-encoded gp350 glycoprotein to prevent EBV infection. …”
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16251
Deep learning captures the effect of epistasis in multifactorial diseases
Published 2025-01-01“…However, for complex multifactorial diseases such as Alzheimer’s disease, diabetes, cardiovascular disease, cancer, and others, association between individual SNPs and disease could be non-linear due to epistatic interactions. …”
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16252
Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Nondialysis Chronic Kidney Patients
Published 2021-01-01“…The Neutrophil-to-Lymphocyte Ratio (NLR) and the Platelet-to-Lymphocyte Ratio (PLR) are inflammatory biomarkers for several diseases, such as cancer and cardiovascular morbidities; however, there are currently few studies on kidney diseases. …”
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16253
Resección endoscópica de lesiones adenomatosas del colon
Published 2023-03-01“…Desarrollo: La detección de los adenomas constituye un reto de la estrategia de detección precoz del cáncer colorrectal. La polipectomía es la herramienta más importante para su prevención. …”
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16254
Anticancer activity of mixed Graphene/Carbone nanotubes reinforced Sulfur-Containing polyketoamine nanocomposites
Published 2025-01-01“…Methylene blue staining confirmed the suppression of cancer cell growth, particularly with PKA/GNS/MWCNTsd, highlighting their potential for clinical applications.…”
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16255
MORINGA OLEIFERA. APLICACIÓN EN LA ELABORACIÓN DE UN PROTECTOR SOLAR
Published 2024-11-01“…Esto se debe a que poseen en su composición compuestos con actividad biológica, como compuestos fenólicos, vitaminas y ácidos grasos, imprescindibles para la protección de las células vivas, del daño oxidativo asociado con el envejecimiento, el cáncer y las enfermedades degenerativas.…”
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16256
Insight into the current practice of ototoxicity monitoring during cisplatin therapy
Published 2021-03-01“…Patients with Head and Neck Cancer (HNC) represented the largest subgroup that received cisplatin (n = 122, 32.2%) and demonstrated higher rates of ototoxicity counseling (n = 103, 84.4%) and pretreatment audiograms (n = 70, 57.4%) compared to the non HNC group (n = 36, 36.2%, P < 0.0001 and n = 22, 8.5%, P < 0.0001). …”
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16257
Oral health risks in adults who use electronic nicotine delivery systems and oral nicotine pouches: a critical review of the literature and qualitative synthesis of the available e...
Published 2024-12-01“…Results The qualitative meta-analysis revealed that comparisons of EC versus NU groups yielded mean scores of 0.29 for pre-cancerous lesions (N = 14 observations), 0.27 for inflammatory processes (N = 83), 0.43 for oral clinical parameters (N = 93) and 0.70 for shifts in the oral microbiome (N = 10). …”
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16258
Características sociodemográficas y condiciones de riesgo de la persona adulta mayor en situación de pobreza extrema frente a la pandemia por COVID-19
Published 2022-12-01“…Respecto a las condiciones de riesgo vinculadas a enfermedades prevalentes, el 0,26 % de personas adultas mayores señalaron que presentan diabetes; el 0,26 %, hipertensión arterial; el 1,49 %, enfermedad cardiovascular; el 0,66 %, enfermedad pulmonar, y el 0,86 %, cáncer. Respecto a la sintomatología vinculada a la COVID-19, el 0,51 % de personas adultas mayores contactadas presentaron fiebre; el 0,18 %, tos; el 0,12 %, dificultad respiratoria; el 0,18 %, congestión nasal, y el 0,18 %, dolor de garganta. …”
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16259
Pharmacognostic Characterization of Panchatikta, an Ayurvedic Polyherbal Combination—Exploring the Role of Botanical and Phytochemical Techniques in the Standardization and Validat...
Published 2024-01-01“…As Panchatikta is prescribed for various life-threatening diseases including cancer, the standards developed here ensure the authenticity of the ingredients, which in turn ensures the quality of the prepared medicines.…”
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16260