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16221
Dietetic service provision and nutritional interventions provided to patients with head and neck sarcoma: Findings from a national United Kingdom centre five-year audit
Published 2024-03-01“…Malnutrition is common in head and neck cancer (HNC) but limited literature exists determining nutritional interventions required in HNS. …”
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16222
Impact of hospital formulary intervention on carbapenem use: a segmented time-series analysis of consumption and a propensity score-matched non-inferiority study of treatment effic...
Published 2025-01-01“…To assess treatment efficacy, we used non-inferiority analysis with propensity score matching based on age, sex, body mass index, cancer status, and baseline blood test results. The treatment outcomes were evaluated using predefined clinical indicators. …”
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16223
Epidemiology and clinical features of childhood malignant solid tumors in a single center in southwest China over 24 years
Published 2025-01-01“…They were classified according to the International Classification of Childhood Cancer, Third Edition (ICCC-3). A retrospective analysis was conducted on the disease spectrum composition and trends, distribution among different age groups and genders, and hospitalization characteristics of the patients. …”
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16224
MammaPrint Feasibility in a Large Tertiary Urban Medical Center: An Initial Experience
Published 2012-01-01“…The MammaPrint (MP) diagnostic assay stratifies breast cancer patients into high- and low-risk groups using mRNA analysis of a 70-gene profile. …”
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16225
Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database
Published 2025-01-01“…Patients and methods Differentially expressed genes (DEGs) of glioma were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. …”
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16226
Protocol for a randomised ‘screen-and-treat’ Helicobacter pylori eradication trial in 14–18-years-old adolescents residing in three regions of Chile: effectiveness and microbiologi...
Published 2025-01-01“…Introduction Gastric cancer is a major global health concern, being the final stage of a long-term process, primarily associated with Helicobacter pylori (H. pylori) infection. …”
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16227
Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1
Published 2025-01-01“…Data from RNA‐seq and microarray were analyzed to reveal correlations of the CENPM gene with cancer, metastasis, and survival in ACC. Immunohistochemistry was used to assess CENPM protein expression. …”
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16228
Population pharmacokinetics of iruplinalkib in healthy volunteers and patients with solid tumors
Published 2025-01-01“…Abstract Iruplinalkib (WX‐0593), a selective oral ALK/ROS1 tyrosine kinase inhibitor, was approved in China as first‐line therapy for ALK‐positive non‐small‐cell lung cancer (NSCLC) and for the treatment of locally advanced or metastatic ALK‐positive NSCLC that has progressed following crizotinib therapy. …”
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16229
Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations
Published 2025-12-01“…Hepatitis B virus (HBV) DNA integration into the host cell genome is reportedly a major cause of liver cancer, and a source of hepatitis B surface antigen (HBsAg). …”
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16230
Impacts of Sandstorms on Chemistries of Ambient PAHs in a Small City in North China
Published 2023-03-01“…Accordingly, the largest contributor of incremental lifetime cancer risks (ILCRs) changed from vehicle exhaust (VE) (36.2%) in the NSSP to OLC (34.4%) in the SSP. …”
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16231
Comparative Evaluation of Functional Outcomes in High Condylar Fractures Treated with Closed Methods with and without Temporomandibular Joint Arthrocentesis: A Research Protocol fo...
Published 2025-02-01“…Materials and Methods: A randomised controlled trial will be conducted at Siddharth Gupta Memorial Cancer Hospital, Sawangi, Wardha, Maharashtra, India, from September 2024 to May 2026, involving 10 patients. …”
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16232
Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database
Published 2025-01-01“…In terms of sex, the risk of cancer was higher in men compared to women in the infliximab-only and combination groups; however, no sex difference was observed in the azathioprine-only group. …”
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16233
Screening high-risk Veterans for cirrhosis: taking a stepwise population health approach
Published 2025-01-01“…Of 488 patients whose charts were reviewed, 230 were excluded from outreach based on predefined criteria (e.g., advanced cancer, prior or current referral to hepatology). …”
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16234
Unlocking melanoma Suppression: Insights from Plasma-Induced potent miRNAs through PI3K-AKT-ZEB1 axis
Published 2025-02-01“…Introduction: Melanoma is a rare but highly malignant form of skin cancer. Although recent targeted and immune-based therapies have improved survival rates by 10–15%, effective melanoma treatment remains challenging. …”
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16235
Exploring the role of curcumin in mitigating oxidative stress to alleviate lipid metabolism disorders
Published 2025-01-01“…An increasing body of research indicates that disorders of lipid metabolism can contribute to the development and progression of various diseases, including hyperlipidemia, obesity, non-alcoholic fatty liver disease (NAFLD), diabetes mellitus, atherosclerosis, and cancer, potentially leading to poor prognoses. The activation of the oxidative stress pathway disrupts lipid metabolism and induces cellular stress, significantly contributing to metabolic disorders. …”
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16236
Structural Properties, Cytotoxicity, and Anti-Inflammatory Activity of Silver(I) Complexes with tris(p-tolyl)Phosphine and 5-Chloro-2-Mercaptobenzothiazole
Published 2010-01-01“…The in vitro testing of cytotoxic activity of 1–5 against leiomyosarcoma cancer cells (LMS), were evaluated with Trypan Blue and Thiazolyl Blue Tetrazolium Bromide or 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide (MTT) assays. …”
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16237
PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database
Published 2025-01-01“…BackgroundTransplant recipients face increased cancer mortality due to immunosuppressive treatments. …”
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16238
Manganese-based immunotherapy synergized with novel supramolecular hydrogel: Advancing localized immune activation strategies in squamous cell carcinoma
Published 2025-02-01“…These findings indicate that the Mn-αPD-1-loaded in situ sustained-release G-TA-I hydrogel represents a novel, safe, and effective cancer therapeutic drug delivery system that can maximize the efficacy of immunotherapy and reduce the side effects of immunotherapy. …”
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16239
Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs
Published 2018-01-01“…This finding offers opportunity to dogs with cancer that might require long-term administration of DOX without adverse effects.…”
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16240
Reduced irradiation exposure areas enhanced anti-tumor effect by inducing DNA damage and preserving lymphocytes
Published 2024-12-01“…Methods In mouse breast cancer models, we compared the anti-tumor effects of RTRT and conventional radiotherapy (CNRT) by assessing tumor growth, metastasis, and survival rates. …”
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