Associations between physical activity, sedentary behavior, and health risk behaviors among adolescents from a city in Southern Brazil by Michael Pereira da Silva, Fabio Eduardo Fontana, Gregory J. Welk, Pedro F. Saint-Maurice, Edmar Roberto Fantineli, Eliane Denise Araújo Bacil, Wagner de Campos

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Factors Associated with Fluid Sequestration in Patients with Acute Pancreatitis: A Prospective Study in Tertiary Centre Hospital in Nepal by Raju Bhandari, Krishna Sapkota, Seema Subedi, Som Kumar Shrestha, Edward Sutanto, Prabhat Jha, Ramesh Singh Bhandari

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High Expression of Ten Eleven Translocation 1 Is Associated with Poor Prognosis in Hepatocellular Carcinoma by Haopeng Wen, Tengfei Ji, Liteng Lin, Nan Cheng, Kangshun Zhu, Liangqi Cao

“…However, the effect of DNA demethylation enzymes, ten eleven translocation (TET) proteins, has not been comprehensively characterized in liver cancer. In this research, we sought to unravel the linkage of TET proteins with prognosis, immune characteristics and biological pathways in hepatocellular carcinoma (HCC). …”
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Factors associated with, and variations in, COVID-19 hospital death rates in England’s first two waves: observational study by Alex Bottle, Paul Aylin, Stephen Brett, Puji Faitna

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A Retrospective Observational Cohort Analysis of Oncology Patients with Febrile Neutropenia in the Emergency Department of a Tertiary Care Hospital in Oman by Badar Al-Aamri, Aisha AL Breiki, Darpanarayan Hazra, Talib Al-Aamri, Manar Al-Shehi

“…Most patients (89.3%) presented with active cancer, and the mean neutrophil count was 0.18. High-risk patients exhibited significantly higher rates of positive blood cultures (31.6% vs. 1.6%) and positive urine cultures (20.8% vs. 7.7%). …”
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Radio-protective effects of ultra-fine bubble hydrogen water and serum protein responses in whole-body radiation-exposed mice by Masaru Yamaguchi, Khin Thandar Htun, Youta Tatara, Yoshiaki Sato, Masato Hosoda, Suchart Kothan, Chikashi Kamimura, Osamu Inanami, Ikuo Kashiwakura

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Advancing Therapeutic Strategies with Polymeric Drug Conjugates for Nucleic Acid Delivery and Treatment by Ullah A, Khan M, Zhang Y, Shafiq M, Ullah M, Abbas A, Xianxiang X, Chen G, Diao Y

“…Applications of PDCs in treating diseases such as cancer, immune disorders, and fibrosis are also discussed. …”
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Enhance health evidence quality in classification tasks: A triangulation approach utilizing case-based reasoning and process features by Ruihua Guo, Ross Smith, Qifan Chen, Angus Ritchie, Simon Poon

“…Objective Machine learning (ML) has enabled healthcare discoveries by facilitating efficient modeling, such as for cancer screening. Unlike clinical trials, real-world data used in ML are often gathered for multiple purposes, leading to bias and missing information for a specific classification task. …”
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Prediction Scores Do Not Correlate with Clinically Adjudicated Categories of Pulmonary Embolism in Critically Ill Patients by CM Katsios, M Donadini, M Meade, S Mehta, R Hall, J Granton, J Kutsiogiannis, P Dodek, D Heels-Ansdell, L McIntyre, N Vlahakis, J Muscedere, J Friedrich, R Fowler, Y Skrobik, M Albert, M Cox, J Klinger, J Nates, A Bersten, C Doig, N Zytaruk, M Crowther, DJ Cook

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TMEM101 expression and its impact on immune cell infiltration and prognosis in hepatocellular carcinoma by Lingyun Kuang, Yilin Pang, Quangang Fang

“…Abstract Hepatocellular carcinoma (HCC) is a cancer caused by inflammation, which affects the immune response and treatment outcomes. …”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…Apcmin/+ mice, which harbour a germline Apc mutation (g.2549T>A) associated with multiple intestinal neoplasms, are extensively employed in colorectal cancer research. In this study, we used Apc as a model and assessed the feasibility of different qPCR-based methods for SNV genotyping, considering approaches with and without genotyping analytical tools. …”
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Utilização de DNA Tumoral Circulante na Análise de Prognóstico de Pacientes com Tumores Malignos Sólidos do Trato Gastrintestinal: Revisão Sistemática by Gabriel dos Santos Martins de Abreu, Mariana Albuquerque de Brito, Ana Paula de Souza Ramos

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Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma by Miaodong Wang, Qin He, Zeshan Chen, Yijue Qin

“…We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microRNA, long non-coding RNA, somatic mutation, and DNA methylation data, from the sxdyc website. …”
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Autoimmune Factor V Deficiency That Took 16 Years to Diagnose due to Pseudodeficiency of Multiple Coagulation Factors by Takaaki Kato, Takaya Hanawa, Mea Asou, Tomohiko Asakawa, Hisashi Sakamaki, Makoto Araki

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Efectos del vapeo sobre la salud bucodental by Cristian Camilo Morales Lastre, Ronald Duvan Hurtado Pacheco, Midian Clara Castillo Pedraza

“…El vapeo también incrementa el riesgo de caries dental, xerostomía, candidiasis oral, alteración de la estética dental y puede inducir cáncer oral. Además, los cigarrillos electrónicos pueden explotar y causar graves lesiones bucales, que incluyen fracturas dentoalveolares, luxaciones, avulsiones, formación de hematomas, entre otras. …”
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Anti-Inflammatory Activities of Some Plants of Genus Alpinia: Insights from In Vitro, In Vivo, and Human Studies by Yuliawati KM, Febriyanti RM, Sumiwi SA, Levita J

“…These plants did not show toxicity toward numerous normal cell lines (RAW 264.7, IEC-6, HepG2, MT-4, NIH-3T3, Vero cells, human peripheral blood mononuclear cells, and HaCaT) but were toxic to cancer cell lines (HT29). In humans, A. galanga was studied for its effects as psychostimulants improving mental health, improving sperm motility, and erectile dysfunction. …”
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Síndrome De Burnout Em Profissionais De Enfermagem Oncológica: Um Estudo Transversal by Aline de Jesus Garcia, André da Silva dos Santos, Claudeone Vieira Santos, Matheus dos Santos Ferreira, Magno Merces Weyll Pimentel

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Risk Factors Associated with Falls and Fractures Following Prescription of Opioids Among Privately Insured Patients with Osteoarthritis by Stuart Silverman, Patricia Schepman, J. Bradford Rice, Craig G. Beck, William Pajerowski, Alan G. White, Sheena Thakkar, Rebecca L. Robinson, Birol Emir

“…**Methods:** Optum Healthcare Solutions, Inc data (January 2012–March 2017) were used to identify patients over 18 with at least 2 diagnoses of hip and/or knee OA, and at least 90 days’ supply of opioids. Patients with cancer were excluded. Falls or fractures outcomes were assessed in the 36-month follow-up period after the date of the first opioid prescription after first OA diagnosis. …”
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Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination by Saad Shakir, Samantha Lane, Alison Yeomans

“…Reports with comorbidities or concurrent medication indicative of transplantation, HIV infection or cancer (‘immunocompromised’ population) were compared with each overall database population.Data extraction and synthesis Two researchers extracted data. …”
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Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice by Parinda Jamrus, Nuttanan Pholngam, Benjaporn Kiatpakdee, Kittikun Viwatpinyo, Jim Vadolas, Sukonthar Ngampramuan, Saovaros Svasti, Pornthip Chaichompoo

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