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16021
Virtual online consultations: advantages and limitations (VOCAL) study
Published 2016-01-01“…The study is based in 2 contrasting clinical settings (diabetes and cancer) in a National Health Service (NHS) acute trust in London, UK. …”
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16022
Liposomal Formulations: A Recent Update
Published 2024-12-01“…This review also covers recent preclinical and clinical research showing the therapeutic promise of next-generation liposomal formulations for cancer, infectious diseases, neurological disorders and inflammatory disorders. …”
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16023
Deep unsupervised clustering for prostate auto-segmentation with and without hydrogel spacer
Published 2025-01-01“…In recent years, hydrogel spacers have been used in some prostate cancer patients receiving radiotherapy to separate the prostate and the rectum to better spare the rectum while achieving adequate dose coverage on the prostate. …”
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16024
Development of the therapeutic regimen based on the synergistic activity of cyclophosphamide and double-stranded DNA preparation which results in complete cure of mice engrafted wi...
Published 2016-12-01“…Following CP treatment and massive apoptosis of committed cancer cell subpopulation, we observed relative increase in TISC percentage, which is consistent with reduced susceptibility of TISCs to CP. …”
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16025
Evaluation of Leea rubra Leaf Extract for Oxidative Damage Protection and Antitumor and Antimicrobial Potential
Published 2021-01-01“…EAF may have great importance in preventing oxidative damage to DNA, erythrocytes, and other cellular components as well as can be a good candidate in cancer chemotherapy and treating infectious diseases caused by antibiotic-resistant bacteria.…”
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16026
Changes in scanning orientation effects of Gafchromic EBT-3 film irradiated with ultra-high dose rate proton beams
Published 2025-01-01“…Abstract While the FLASH radiotherapy (FLASH RT) using ultra-high-dose-rate (UHDR) proton beams has the potential to achieve more effective cancer treatment, reliable and practical dosimetry of UHDR beams remains challenging. …”
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16027
Essential core competencies for scope of practice of paediatric oncology nurses in Latin America: a scoping review protocol
Published 2022-07-01“…Introduction Nurses comprise the largest group of health workers globally and are essential to the provision of care necessary for delivering curative therapy to children with cancer. In high-income countries, previous studies of the nurse workforce have shown an association between patient morbidity and mortality and nursing-related factors such as staffing, education and the nursing practice environment. …”
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16028
Single-cell RNA-seq analysis reveals microenvironmental infiltration of myeloid cells and pancreatic prognostic markers in PDAC
Published 2025-01-01“…Methods Single-cell RNA sequencing (scRNA-seq) data were downloaded from t the Tumor Immune Single-cell Hub and gene expression data were retrieved from The Cancer Genome Atlas (TCGA) database and the Gene Expression Omnibus (GEO) database. …”
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16029
Sessile Serrated Lesions: Searching for the True Prevalence and Risk Factors in China
Published 2025-01-01“…Background/Aims: Growing recognition identifies sessile serrated lesions (SSL) as colorectal cancer (CRC) precursors. However, the SSL detection rate remains debatable and lacks a definitive consensus. …”
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16030
Genetic mechanisms of the influence of light and phototransduction on Drosophila melanogaster lifespan
Published 2018-11-01“…Numerous literature sources establish a connection between the duration of exposure to daylight, carcinogenesis and longevity, convincingly showing a significant reduction in the incidence of cancer in blind people, as well as in animal models. …”
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16031
Delayed-release prednisone improves fatigue and health-related quality of life: findings from the CAPRA-2 double-blind randomised study in rheumatoid arthritis
Published 2015-08-01“…General quality of life was assessed using the general score and individual domains of Functional Assessment of Cancer Therapy-General (FACT-G) and SF-36.Results The change from baseline to week 12 in FACIT-F score was statistically significantly different with DR prednisone/DMARD (3.8) versus placebo/DMARD (1.6; difference 2.2, p=0.0032). …”
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16032
Cobalt oxide nanoparticles induce cytotoxicity and excessive ROS mediated mitochondrial dysfunction and p53-independent apoptosis in melanoma cells
Published 2025-01-01“…Abstract Nanotherapy has emerged as a promising strategy for the targeted and efficient treatment of melanoma, the most aggressive and lethal form of skin cancer, with minimized systemic toxicity. However, the therapeutic efficacy of cobalt oxide nanoparticles (Co3O4NPs) in melanoma treatment remains unexplored. …”
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16033
Patterns and predictors of mortality in a semi-urban population-based cohort in Sri Lanka: findings from the Ragama Health Study
Published 2020-09-01“…We determined the survival probability of the cohort over 10 years and estimated Hazard ratios (HRs) for all-cause mortality (ACM), cardiovascular mortality (CVM) and cancer-related mortality (CRM) using Cox’s proportional hazards model. …”
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16034
Machine Learning Based on a Multiparametric and Multiregional Radiomics Signature Predicts Radiotherapeutic Response in Patients with Glioblastoma
Published 2020-01-01“…Although radiotherapy has become one of the main treatment methods for cancer, there is no noninvasive method to predict the radiotherapeutic response of individual glioblastoma (GBM) patients before surgery. …”
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16035
In Vitro Antibacterial, Antioxidant, Cytotoxicity Activity, and In Silico Molecular Modelling of Compounds Isolated from Roots of Hydnora johannis
Published 2024-01-01“…The cytotoxicity of extracts from roots of H. johannis was conducted against MCF-7 cell lines (human breast cancer) by MTT assay. According to the cytotoxicity study, n-hexane extract exhibited a high level of toxicity with 28.9 ± 5.6% cell viability. …”
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16036
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16037
Associations of neutrophil/high-density lipoprotein cholesterol ratio with frailty and its mortality
Published 2025-01-01“…In addition, the survival analysis revealed that NHR was significantly positively associated with all-cause (HR: 1.12, 95% CI: 1.07-1.17, P < 0.0001), cardiocerebrovascular disease (CCD)-specific (HR: 1.21, 95% CI: 1.11-1.33, P < 0.0001), and cancer-specific mortality risks (HR: 1.13, 95% CI: 1.07-1.19, P < 0.0001) in frail individuals.ConclusionIn the American adult population, NHR maintains a J-shaped relationship with frailty. …”
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16038
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16039
Catastrophic Brain Aspergillosis after Liver Transplantation
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16040