Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction by Ernesto Bustinza-Linares, Francisco Socola, Vinicius Ernani, Shelly A. Miller, Jonathan C. Trent

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Computational assessment of measurable residual disease in acute myeloid leukemia using mixture models by Tim R. Mocking, Angèle Kelder, Tom Reuvekamp, Lok Lam Ngai, Philip Rutten, Patrycja Gradowska, Arjan A. van de Loosdrecht, Jacqueline Cloos, Costa Bachas

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The care needs of persons with oropharyngeal dysphagia and their informal caregivers: A scoping review. by Aurora Ninfa, Valeria Crispiatico, Nicole Pizzorni, Marta Bassi, Giovanni Casazza, Antonio Schindler, Antonella Delle Fave

“…Research methods primarily consisted of qualitative interviews and focus groups (14 studies, 93.3%); head and neck cancer was the most frequent cause of patients' dysphagia (8 studies, 53.3%); caregivers' perspective was seldom investigated (5 studies, 33.3%). …”
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Carotid endarterectomy in the setting of persistent hypoglossal artery by Samuel D. Leonard, MD, Lili Sadri, MD, Hung Nguyen, MD, Naveed Saqib, MD, Marvin Heck, MD, Gordon Martin, MD

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Views and opinions of the general public about the reimbursement of expensive medicines in the Netherlands. by Féline E V Scheijmans, Roosmarijn van der Wal, Margot L Zomers, Johannes J M van Delden, W Ludo van der Pol, Ghislaine J M W van Thiel

“…<h4>Objectives</h4>Solidarity-based healthcare systems are being challenged by the incremental costs of new and expensive medicines for cancer and rare diseases. To regulate reimbursement of such drugs, the Dutch government introduced a policy instrument known as the Coverage Lock (CL) in 2015. …”
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A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review by Manuel De Jesus Encarnacion Ramirez, Gervith Reyes Soto, Carlos Castillo Rangel

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Tobacco Stained Fingers and Its Association with Death and Hospital Admission: A Retrospective Cohort Study. by Gregor John, Céline Louis, Amandine Berner, Daniel Genné

“…Multivariable Cox models were used to adjust for confounding factors: age, gender, pack-year unit smoked, cancer, harmful alcohol use and diabetes. The number of hospital admissions was compared through a negative binomial regression and adjusted for the follow-up time, diabetes, and alcohol use.…”
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Altered Protein Structures and Neoepitopes in Lupus Neutrophils From Dysregulated Splicing of Messenger RNA by Rayan Najjar, Xiaoxing Wang, Jose Mario Bello Pineda, Hugh Alessi, Alison Bays, Robert K. Bradley, James N. Jarvis, Tomas Mustelin

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Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment by Liu Y, Si L, Jiang Y, Jiang S, Zhang X, Li S, Chen J, Hu J

“…Yunheng Liu,1,&ast; Longqing Si,1,&ast; Yuxuan Jiang,1,&ast; Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. Researchers have developed various types of pH-responsive nanomaterials based on the tumor acidic microenvironment. …”
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A scoping review on the use of traditional medicine and oral health in Africa. by Moréniké Oluwátóyìn Foláyan, Mobolaji Timothy Olagunju, Olunike Rebecca Abodunrin, Omolola Titilayo Alade

“…Other oral disorders managed include halitosis, jaw fracture, and oral cancer.<h4>Conclusions</h4>Given the increasing prevalence of oral diseases within the region, the shortage of oral healthcare professionals and limited access to financial resources, it becomes imperative to support the generation of empirical evidence to enhance the provision of traditional medicine for oral healthcare in Africa.…”
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Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome by Vadim Gorodetskiy, Wolfram Klapper, Natalya Probatova, Vladimir Vasilyev

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A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis. by Courtney A Granville, Regan M Memmott, Andria Balogh, Jacopo Mariotti, Shigeru Kawabata, Wei Han, Jaclyn Lopiccolo, Jason Foley, David J Liewehr, Seth M Steinberg, Daniel H Fowler, M Christine Hollander, Phillip A Dennis

“…These studies support clinical testing of rapamycin or other agents that target Treg in K-Ras driven human lung cancer.…”
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Comparison of Liver Biopsy Findings with the Digestive Disease Week Japan 2004 Scale for Diagnosis of Drug-Induced Liver Injury by Akemi Tsutsui, Yasuni Nakanuma, Kouichi Takaguchi, Satoko Nakamura, Hiroshi Shibata, Nobuyuki Baba, Tomonori Senoh, Takuya Nagano, Hiroko Ikeda

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The volatilome – investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC) by Philipp Opitz, Olf Herbarth

“…Conclusions The systematic pattern analysis of urinary VOMs appears to have potential clinical application as a diagnostic tool for cancer, especially HNSCC.…”
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A Rare Case of Pylephlebitis as a Complication of Cholecystocolonic Fistula by Kouki Imaoka, Saburo Fukuda, Hirofumi Tazawa, Sotaro Fukuhara, Yuzo Hirata, Seiji Fujisaki, Mamoru Takahashi, Hideto Sakimoto

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Current Pharmacological Management of Gastroesophageal Reflux Disease by Yao-Kuang Wang, Wen-Hung Hsu, Sophie S. W. Wang, Chien-Yu Lu, Fu-Chen Kuo, Yu-Chung Su, Sheau-Fang Yang, Chiao-Yun Chen, Deng-Chyang Wu, Chao-Hung Kuo

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Mechanistic insights into endosomal escape by sodium oleate-modified liposomes by Ebrahim Sadaqa, Satrialdi, Fransiska Kurniawan, Diky Mudhakir

“…This study investigates sodium oleate-modified liposomes (SO-Lipo) as an innovative strategy to enhance endosomal escape and improve cytosolic delivery in 4T1 triple-negative breast cancer cells. We aimed to elucidate the mechanistic role of sodium oleate in promoting endosomal escape and compared the performance of SO-Lipo with unmodified liposomes (Unmodified-Lipo) and Aurein 1.2-modified liposomes (AUR-Lipo). …”
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Canadian Thoracic Society: Presenting a New Process for Clinical Practice Guideline Production by Samir Gupta, Onil K Bhattacharyya, Melissa C Brouwers, Elizabeth A Estey, Margaret B Harrison, Paul Hernandez, Valerie A Palda, Louis-Philippe Boulet

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Comparative analysis of alectinib and brigatinib in real-world treatment of advanced NSCLC with ALK rearrangements by Kyuhwan Kim, Kyu Yean Kim, Hye Seon Kang, Ah Young Shin, Sung Kyoung Kim, Chan Kwon Park, Sang Haak Lee, Seung Joon Kim, Jeong Uk Lim, Chang Dong Yeo

“…Background and objectives: This study aimed to compare the efficacy of the second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) alectinib and brigatinib in the treatment of advanced non-small-cell lung cancer (NSCLC) with ALK rearrangements based on real-world data. …”
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Transcriptomic predictors of rapid progression from mild cognitive impairment to Alzheimer's disease by Yi-Long Huang, Tsung-Hsien Tsai, Zhao-Qing Shen, Yun-Hsuan Chan, Chih-Wei Tu, Chien-Yi Tung, Pei-Ning Wang, Ting-Fen Tsai

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