Localized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions by Hasan AM, Cavalu S, Kira AY, Hamad RS, Abdel-Reheim MA, Elmorsy EA, El-kott AF, Morsy K, AlSheri AS, Negm S, Saber S

Subjects: “…gastrointestinal cancer…”
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Plant miRNAs for Improved Gene Regulation in a Wide Range of Human Cancers by Maksym Zoziuk, Vittorio Colizzi, Pavlo Krysenko, Maurizio Mattei, Roberta Bernardini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk

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Improving neuroendocrine tumor treatments with mathematical modeling: lessons from other endocrine cancers by John Metzcar, Rachael Guenter, Yafei Wang, Kimberly M Baker, Kate E Lines

“…Causal or mechanistic mathematical modeling is widely deployed in disease areas such as breast and prostate cancers, aiding the understanding of observations and streamlining in vitro and in vivo modeling efforts. …”
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Blood Genome-Wide Transcriptional Profiles of HER2 Negative Breast Cancers Patients by Ovidiu Balacescu, Loredana Balacescu, Oana Virtic, Simona Visan, Claudia Gherman, Flaviu Drigla, Laura Pop, Gabriela Bolba-Morar, Carmen Lisencu, Bogdan Fetica, Oana Tudoran, Ioana Berindan-Neagoe

“…Peripheral blood samples from seven healthy female donors and 29 women with breast cancer including 14 triple-negative breast cancers and 15 hormone-dependent breast cancers were evaluated by microarray. …”
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Gut Microbiota Secondary Metabolites: Key Roles in GI Tract Cancers and Infectious Diseases by Eman K. E. Anwer, Muhammad Ajagbe, Moustafa Sherif, Abobaker S. Musaibah, Shuaib Mahmoud, Ali ElBanbi, Anwar Abdelnaser

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Meta-analysis of 5-year survival data for cancers without considering time is misleading by Masoud Mohammadi

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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

Subjects: “…Fungating breast cancer…”
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Interval Cancers in a Population-Based Screening Program for Colorectal Cancer in Catalonia, Spain by M. Garcia, X. Domènech, C. Vidal, E. Torné, N. Milà, G. Binefa, L. Benito, V. Moreno

“…Objective. To analyze interval cancers among participants in a screening program for colorectal cancer (CRC) during four screening rounds. …”
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Biological functions of 5-methylcytosine RNA-binding proteins and their potential mechanisms in human cancers by Tingting Zhao, Zhe Zhang, Zhuo Chen, Guozheng Xu, Yongxi Wang, Fang Wang

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Tattoo ink exposure is associated with lymphoma and skin cancers – a Danish study of twins by Signe Bedsted Clemmensen, Jonas Mengel-From, Jaakko Kaprio, Henrik Frederiksen, Jacob von Bornemann Hjelmborg

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Significance of the Lesion–Pleura Relationship in Differentiating Peripheral Inflammatory Lesions and Lung Cancers by Tao Y, Zhang WT, Ding C, Fu BJ, Lv FJ, Chu ZG

“…Yang Tao,* Wen-Tao Zhang,* Can Ding, Bin-Jie Fu, Fa-Jin Lv, Zhi-Gang Chu Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fa-Jin Lv; Zhi-Gang Chu, Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, 1# Youyi Road, Yuanjiagang, Yuzhong District, Chongqing, People’s Republic of China, 400016, Tel +86 18723032809, Fax +86 23 68811487, Email cyscitg@hospital.cqmu.edu.cn; chuzg0815@163.comPurpose: To determine the significance of lesion–pleura relationship in differentiating peripheral inflammatory lesions (PILs) and peripheral lung cancers (PLCs).Patients and Methods: From January 2017 to April 2022, a total of 743 patients with 501 PLCs and 292 PILs (≥ 1.5 cm) were retrospectively enrolled. …”
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Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment by Jeffrey Koury, Li Zhong, Jijun Hao

“…Specifically, aberrant activation of these pathways is implicated in modulation of cancer stem cells (CSCs), a small subset of cancer cells capable of self-renewal and differentiation into heterogeneous tumor cells. …”
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Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon by Jaime Cofre, Eliana Abdelhay

“…Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. …”
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Burdens of Tracheal, Bronchus, and Lung Cancer From 1990 to 2021 in China Compared to the Global Projection of 2036: Findings From the 2021 Global Burden of Disease Study by Yuxing Chen, Qingpeng Zeng, Muyu Li, Jiahui Jin, Jun Zhao

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One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis by Yu Han, Fei Xiao, Qianli Ma, Zhenrong Zhang, Zaiyong Wang, Chaoyang Liang, Deruo Liu

Subjects: “…Multiple primary lung cancers…”
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Effects of Potentially Inappropriate Medications in Older Patients with Gastrointestinal System Cancer by Melike OZKAN, Irfan KARAHAN, Selim YALCIN, Gozde SENGUL AYCICEK

Subjects: “…gastrointestinal system cancers…”
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Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis by Jiasheng Xu, Kaili Liao, Weimin Zhou

“…These cells possess a stemness phenotype with a self-renewal ability and multipotential differentiation which was considered the reason for the failure of conventional cancer therapies and tumor recurrence. However, a highly dynamic equilibrium was found between cancer stem cells and cancer cells, and this indicates that cancer stem cells are no more special target and blocking the transformation of cancer stem cells and cancer cells seem to be a more significant therapy strategy. …”
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Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment by Naofumi Mukaida, So-ichiro Sasaki, Tomohisa Baba

“…The capacity of chemokines to regulate both cancerous and noncancerous cells highlights their crucial roles in cancer development and progression. …”
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Microgravity, Stem Cells, and Cancer: A New Hope for Cancer Treatment by Uğur Topal, Cihan Zamur

“…This review will focus on current knowledge on the impact of the microgravity environment on cancer cells, stem cells, and the biological behavior of cancer stem cells.…”
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The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB) by Vladimir F. Niculescu, Eugenia R. Niculescu

“… Evolutionary cancer cell biology reveals that the majority of cancer hallmarks trace their origins back to the premetazoic era. …”
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