Robust and inducible genome editing via an all-in-one prime editor in human pluripotent stem cells by Youjun Wu, Aaron Zhong, Mega Sidharta, Tae Wan Kim, Bernny Ramirez, Benjamin Persily, Lorenz Studer, Ting Zhou

Get full text

OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer by Qihui Sun, Xiaoqi Zhu, Qi Zou, Yang Chen, Tingting Wen, Tingting Jiang, Xiaojia Li, Fang Wei, Keping Xie, Jia Liu

Get full text

Short- and Long-term Outcomes of One-stage Radical Resection and Anastomosis without Preoperative Decompression and Diverting Stoma between Incomplete Obstructive and Non-obstructi... by Kentaro Sato, Yosuke Fukunaga, Manabu Takamatsu, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Tomohiro Yamaguchi, Takashi Akiyoshi

Get full text

RevCAR-mediated T-cell response against PD-L1-expressing cells turns suppression into activation by Eugenia Crespo, Liliana R. Loureiro, Antonia Stammberger, Lydia Hoffmann, Nicole Berndt, Anja Hoffmann, Claudia Dagostino, Karla E. G. Soto, Luise Rupp, Claudia Arndt, Martin Schneider, Claudia R. Ball, Michael Bachmann, Marc Schmitz, Anja Feldmann

Get full text

Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer by Soomin Kim, Jaemoon Koh, Tae Min Kim, Songji Oh, Soyeon Kim, Jeonghwan Youk, Miso Kim, Bhumsuk Keam, Yoon Kyung Jeon, Dong-Wan Kim, Dae Seog Heo

Get full text

Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing by Alice Perucca, Andrea Gómez Llonín, Oriol Mañé Benach, Clement Hallopeau, Elisa I. Rivas, Jenniffer Linares, Marta Garrido, Anna Sallent-Aragay, Tom Golde, Julien Colombelli, Eleni Dalaka, Judith Linacero, Marina Cazorla, Teresa Galan, Jordi Pastor Viel, Xavier Badenas, Alba Recort-Bascuas, Laura Comerma, Patricia Fernandez-Nogueira, Ana Rovira, Pere Roca-Cusachs, Joan Albanell, Xavier Trepat, Alexandre Calon, Anna Labernadie

Get full text

The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study by Ruotong Wang, Shaodi Wen, Xiaoyue Du, Jingwei Xia, Bowen Hu, Yihan Zhang, Guoren Zhou, Feng Jiang, Xiaomin Lu, Miaolin Zhu, Xinyu Xu, Bo Shen

Get full text

Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis by Phuong T.T. Nguyen, Mia Shiue, Nina Kuprasertkul, Pedro Costa-Pinheiro, Luke T. Izzo, Laura V. Pinheiro, Hayley A. Affronti, Gabriel Gugiu, Shivani Ghaisas, Joyce Y. Liu, Jordan C. Harris, Charles W. Bradley, John T. Seykora, Xiaolu Yang, Taku Kambayashi, Clementina Mesaros, Brian C. Capell, Kathryn E. Wellen

Get full text

VHL Genetic Alteration in CCRCC Does Not Determine De-Regulation of HIF, CAIX, hnRNP A2/B1 and Osteopontin by Michelle J. Nyhan, Shereen M. El Mashad, Tracey R. O’Donovan, Sarfraz Ahmad, Chris Collins, Paul Sweeney, Eamonn Rogers, Gerald C. O’Sullivan, Sharon L. McKenna

Get full text

Expanding the miRNA Transcriptome of Human Kidney and Renal Cell Carcinoma by Adam P. Sage, Brenda C. Minatel, Erin A. Marshall, Victor D. Martinez, Greg L. Stewart, Katey S. S. Enfield, Wan L. Lam

Get full text

KRAS Transitions and Villous Growth in Colorectal Adenomas by Mauro Risio, Davide Malacarne, Walter Giaretti

Get full text

Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes by Yong Li, Steven A Rosenberg, Paul F Robbins, Zhiya Yu, Maria Parkhurst, Billel Gasmi, Nikolaos Zacharakis, Todd D Prickett, Jared J Gartner, Sri Krishna, Stephanie L Goff, Satyajit Ray, Frank J Lowery, Sivasish Sindiri, Alakesh Bera, Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Lior Levy, Tiffany Benzine, Robert V Masi, Rafiqul Islam

Get full text

B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer by Nicole J. Toney, Lynn M. Opdenaker, Lisa Frerichs, Shirin R. Modarai, Aihui Ma, Holly Archinal, Grace O. Ajayi, Jennifer Sims-Mourtada

Get full text

Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib) by Xiguang Chen, Qiting Zeng, Liyang Yin, Bingru Yan, Chen Wu, Jianbo Feng, Ying Wu, Jun He, Wenjun Ding, Jing Zhong, Yingying Shen, Xuyu Zu

Get full text

Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma by Zeynep Kacar, Eric Slud, Doron Levy, Julián Candia, Anuradha Budhu, Marshonna Forgues, Xiaolin Wu, Arati Raziuddin, Bao Tran, Jyoti Shetty, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin Wei Wang

Get full text

Sleeve gastrectomy reveals the plasticity of the human gastric epithelium by Amit Elad, Botros Moalem, Dana Sender, Aya Bardugo, Ki-Suk Kim, Yhara Arad, Haya Benhayon, Ayelet Gal Etzyoni, Nehemia Greenstein, Aviv Halfon, Sarah Knapp, Michelle Malis, Bailey Peck, Itia Samuel, Amram Kupietzky, Saleh Daher, Esther Forkosh, David Hakimian, Tiberiu Hershcovici, Nadav Ilani, Lior Katz, Moshe Rottenstreich, Elez Vainer, Yuval Ishay, Eitan Zlotnick, Abed Nasereddin, Idid Shiff, Ariel Benson, Ronit Grinbaum, Siddhartha Mishra, Shlomi Kotler, Linda C. Samuelson, Darleen A. Sandoval, Rachel Ben-Haroush Schyr, Danny Ben-Zvi

Get full text

Wogonin effects on the efflux transporters BCRP and MRP2, explain its effectiveness in ulcerative colitis: Implications for metabolic and transport interactions by Yuanyuan Liu, Zerong Zhang, Xiaoyan Li, Qinghong Hu, Zhangyu Jiang, Jia Lv, Jiayi Xue, Dongyu Wang, Jianxiong Cao, Lingyu Li, Xiaowen Ou, Lijun Zhu, Zhongqiu Liu, Tao Su

Get full text

Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition by Yasmin F Melzer, Nadine L Fergen, Christian Mess, Julia-Christina Stadler, Glenn Geidel, Ysabel A Schwietzer, Julian Kött, Klaus Pantel, Stefan W Schneider, Jochen Utikal, Ewa Wladykowski, Sabine Vidal-y-Sy, Alexander T Bauer, Christoffer Gebhardt

Get full text

SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer by Lutfi H. Alfarsi, Rokaya El Ansari, Busra Erkan, Ali Fakroun, Madeleine L. Craze, Mohammed A. Aleskandarany, Kiu Wai Cheng, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

Get full text

Corrigendum to “Wnt5a Signaling in Normal and Cancer Stem Cells” by Yan Zhou, Thomas J. Kipps, Suping Zhang

Get full text