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Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles
Published 2025-12-01“…PD-L1 can also be incorporated into cancer cell-derived extracellular vesicles (EVs), and EV-associated PD-L1 can inactivate T-cells within the tumor microenvironment. …”
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Ultrasound Microbubble-Mediated microRNA-505 Regulates Cervical Cancer Cell Growth via AKT2
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Exploring the interactions of rapamycin with target receptors in A549 cancer cells: insights from molecular docking analysis
Published 2025-01-01“…Also reports on the binding of rapamycin to cancer cell receptors are limited to the serine/threonine protein kinase mTORC1. …”
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165
Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells
Published 2019-03-01“…The results show significant ability of HUM and especially of CAO to enhance the anti-proliferative effects of FU and OxPt in cancer cell lines Caco-2 and SW-620. On the other hand, VAL and NER are ineffective. …”
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Nano–bio surface interactions, cellular internalisation in cancer cells and e‐data portals of nanomaterials: A review
Published 2021-08-01“…Thus, the present review emphasises the impact of coated, uncoated NMs, size and charge, nature of proteins on nano–bio surface interactions and on internalisation with specific focus on cancer cells. The increased activity of NPs may also result in toxicity on health and environment, thus emphasis should be given to assess the toxicity of NMs in the medical field. …”
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Assessment of Morphological Changes in Breast Cancer Cells Following X-Ray Radiation Utilizing Digital Holographic Microscopy
Published 2025-01-01“…The primary objective of this investigation is to scrutinize the capability of a digital holographic microscope in assessing the morphological transformations of cancer cells exposed to X-ray radiation. Materials and Methods: The Michigan Cancer Foundation-7 (MCF7) cell line underwent exposure to X-ray radiation, administered in a singular fraction at a dose of 2 Gy. …”
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Effects of Pleurotus Eryngii (DC.) Quél. Mushroom Extracts on Cell Proliferation in Breast and Colon Cancer Cell Lines
Published 2024-09-01“…Then, breast (MDA-MB-231, BT-549, BT-20, MCF-7) and colon (HT-29) cancer cell lines were treated with the extracts in increasing concentrations (0.05-0.5 mg/mL) for 48 h. …”
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GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling
Published 2021-01-01“…Ectopic expression of GTSE1 in lung cancer cells significantly increased while knockdown of GTSE1 decreased cell proliferation, cell migration, and cell invasion in H460 and A549 cells. …”
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miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1
Published 2013-01-01“…MicroRNAs (miRNAs) have been implied to play crucial roles for epithelial-to-mesenchymal transition (EMT) of non-small-cell lung cancer cells (NSCLC cells). Here we found that the expression of miR-149, downregulated in lung cancer, was inversely correlated with invasive capability and the EMT phenotype of NSCLC cells. miR-149 inhibited EMT in NSCLC cells. …”
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Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells
Published 2024-12-01“…Overexpression of c-Myc and BIRC5 has been reported in prostate cancer cells which contribute to the development of the tumour environment. …”
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High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
Published 2022-01-01“…UPK3A was highly expressed in human gastric cancer cell lines compared to that in a normal human gastric epithelial cell line. …”
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Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosis
Published 2025-01-01“…Thus, our results demonstrate that the cascade of autophagic flux and LD formation plays an essential role in sustaining mitochondrial fitness to promote cancer cell survival under chronic acidosis. Our findings provide insight into the pro-survival metabolic plasticity in cancer cells under microenvironmental or therapeutic stress and imply that this pro-survival cascade may potentially be targeted in cancer therapy.…”
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Dataset of transcriptomic changes induced by naringenin treatment in MCF-7 breast cancer cellsGene Expression Omnibus
Published 2025-04-01“…Pathway analysis included in our dataset shows upregulation of genes associated with estrogen signaling and epithelial-to-mesenchymal transition in breast cancer cells treated with naringenin.…”
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Development and Evaluation of selective nitroxanthone Derivatives: A promising compound for Targeting MCF-7 breast cancer cells
Published 2025-01-01“…These findings suggest that compound 1 holds promise as a lead compound to target breast cancer cells.…”
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CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells
Published 2025-01-01“…Knockdown of CPSF1 selectively inhibited the growth of prostate cancer cells and reduced glycolytic output. Evaluating the changes in global poly(A) site usage in prostate cancer cells following CPSF1 knockdown revealed widespread usage of intergenic poly(A) sites distal to annotated 3′ UTRs, which lengthened 3′ UTRs and decreased levels of thousands of mRNAs, including key glycolysis genes. …”
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