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Direct current electrical fields inhibit cancer cell motility in microchannel confinements
Published 2025-02-01“…Here we report on the combined impact of micro-confinements and direct current electrical fields (dcEFs) on the motility of MDA-MB-231 human breast cancer cells using a self-developed, easy-to-use platform with microchannels ranging from 3 $$\upmu$$ μ m to 11 $$\upmu$$ μ m in width and 11 $$\upmu$$ μ m height. …”
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42
Synergistic Effect of Geranylgeranyltransferase Inhibitor, GGTI, and Docetaxel on the Growth of Prostate Cancer Cells
Published 2012-01-01“…GGTI also inhibited the prostate cancer cell growth and the growth inhibitory effect was augmented by a combination with docetaxel. …”
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43
Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types
Published 2025-02-01“…Our results suggest that GPR68 is a key mediator of cancer cell radioresistance activated by acidic tumor microenvironment.…”
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Expression of Tropomyosin 1 Gene Isoforms in Human Breast Cancer Cell Lines
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45
Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation
Published 2025-01-01“…RT-PCR, western blot, lentiviral-mediated gene overexpression, and pharmacological inhibitor assays were comprehensively designed to regulate the identified signaling pathways and confirm the mechanism of tanshinlactone. Human breast cancer cell lines-derived xenograft tumor explants assay was used to evaluate the compound’s efficacy and to assess the induction of methuosis via NRF2 activation by tanshinlactone.ResultsTanshinlactone selectively inhibits the growth of ER+ and HER2+/EGFR + breast cancer cells while showing limited cytotoxicity against other cancer types and normal cells. …”
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In vitro anticancer effects of frankincense and its nanoemulsions for enhanced cancer cell targeting
Published 2025-02-01“…FO-NEs exhibit potent anticancer activity, particularly against drug-resistant cancer cell lines, suggesting their potential as a viable strategy for improving the therapeutic efficacy of frankincense in cancer treatment.…”
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Developing anti-TDE vaccine for sensitizing cancer cells to treatment and metastasis control
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48
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
Published 2025-01-01“…Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability. …”
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49
Advances in Surface Plasmon Resonance-Based Biosensor Technologies for Cancer Cell Detection
Published 2022-01-01“…It may become a fast method of detecting cancerous cells and the several variants of corona and other viruses that become pandemic. …”
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50
Levistolide A and periplogenin inhibit the growth of gastric cancer cells in vitro and in vivo
Published 2023-03-01“…In nude mice bearing gastric cancer cells, injection (i.p.) of LA or PPG alone inhibited the growth of the cancer cells. …”
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Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration
Published 2025-01-01“…Cancer-related deaths primarily occur due to metastasis, a process involving the migration and invasion of cancer cells. In most solid tumors, metastasis occurs through collective cell migration (CCM), guided by “cellular leaders”. …”
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Proapoptotic and Antiangiogenic Activities of Arctium Lappa L. on Breast Cancer Cell Lines
Published 2020-01-01“…Furthermore, EHX was found to disrupt the metastatic cascade of breast cancer cells by the inhibition of cell proliferation, migration, invasion, and colonization. …”
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54
Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells
Published 2013-01-01“…In this paper, we describe the metabolic changes as well as the mechanisms of resistance to apoptosis occurring in cancer cells and cancer stem cells, underlying the connection between these two processes.…”
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Expression Profile of Tyrosine Phosphatases in HER2 Breast Cancer Cells and Tumors
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Sociobiology meets oncology: unraveling altruistic cooperation in cancer cells and its implications
Published 2025-01-01“…We also discuss how evolutionary game theory, coupled with contemporary molecular tools, may shed light on understudied mechanisms governing the dynamics of altruistic cooperation in cancer cells. Finally, we discuss how molecular insights gleaned from these mechanistic dissections may fuel advancements in our comprehension of altruism among cancer cells, with implications across multiple disciplines, offering innovative prospects for therapeutic strategies, molecular discoveries, and evolutionary investigations.…”
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Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin
Published 2011-01-01“…To contribute to the understanding of the molecular mechanisms underlying leptin action in breast cancer, our aim was to identify proteins regulated by leptin in MCF-7 human breast cancer cells. Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify proteins affected by leptin. …”
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SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell lines
Published 2025-02-01Subjects: “…breast cancer cell lines…”
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LINC00626 drives tamoxifen resistance in breast cancer cells by interaction with UPF1
Published 2025-01-01“…Additionally, ERα signaling was found to transcriptionally regulate LINC00626 expression, thereby promoting cancer progression and enhancing resistance to tamoxifen in breast cancer cells via the regulation of UPF1 expression. Depletion of LINC00626 restored sensitivity to tamoxifen by activating the PERK-ATF4-CHOP signaling pathway via UPF1. …”
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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence.
Published 2025-02-01“…We here uncover that E6AP silencing in HPV-positive cancer cells ultimately leads to efficient induction of cellular senescence, revealing that E6AP acts as a potent anti-senescent factor in these cells. …”
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