Autoinflammatory Reaction in Dogs Treated for Cancer via G6PD Inhibition by Jonathan W. Nyce

“…Glucose-6-phosphate dehydrogenase (G6PD) is an oncoprotein that is overexpressed in cancer cells to provide the NADPH required for their increased anabolism. …”
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Hydromethanolic extracts of Morus alba L. (Mulberry) young and ripe fruit induces apoptosis in lung carcinoma cells (A549) by Payal Sargara, M. Nataraj, Ramalingam B. Subramanian, Anjali B. Thakkar

“…(mulberry) young and ripe fruit extracts against lung cancer cells. Cancer ranking as the second leading cause of global mortality, it is essential to investigate natural compounds like phytochemicals for therapeutic benefits. …”
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Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells by Jelena Krstic, Juan F. Santibanez

“…Tumor stroma consists of several types of resident cells and infiltrating cells derived from bone marrow, which together play crucial roles in the promotion of tumor growth and metastasis. In cancer cells, TGF-β regulates MMPs expression, while MMPs, produced by either cancer cells or residents’ stroma cells, activate latent TGF-β in the extracellular matrix, together facilitating the enhancement of tumor progression. …”
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Multiple Factors Determine the Oncolytic or Carcinogenic Effects of TLRs Activation in Cancer by Yingxiang Yang, Chengyue Jin, Anthony Yeo, Bo Jin

“…Using TLR ligands as adjuvants induces upregulation of costimulatory signals which in turn activates a cytotoxic leukocyte response against cancer cells. However, TLRs are also overexpressed in human cancer cells resulting in increased cell proliferation, migration, invasion, and angiogenesis. …”
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A fractal–fractional order modeling approach to understanding stem cell-chemotherapy combinations for cancer by Esam Y. Salah, Bhausaheb Sontakke, Ahmed A. Hamoud, Homan. Emadifar, Atul Kumar

“…Abstract The main objective of this work is to study the mathematical model that combines stem cell therapy and chemotherapy for cancer cells. We study the model using the fractal fractional derivative with the Mittag-Leffler kernel. …”
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Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study by Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.

“…Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media consisting of extremely high concentrations of growth factors and glucose. …”
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Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites by Alessandra Viperino, Michael Höpfner, Nicole Edel, Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Imen Ben Abdelmalek, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche

“…They were tested for activity against two liver cancer cell lines (HepG2 and HuH-7) and protozoal parasites (<i>Toxoplasma gondii</i> and <i>Leishmania major</i>). …”
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Exploring the Anticancer Potential of MonoHER (7-Mono-O-(β-Hydroxyethyl)-Rutoside): Mitochondrial-Dependent Apoptosis in HepG2 Cells by Chujie Li, Yue Wang, Jian Liang, Guido R. M. M. Haenen, Yonger Chen, Zhengwen Li, Ming Zhang, Ludwig J. Dubois

“…This study explores the antiproliferative and cytotoxic effects of the semi-synthetic flavonoid MonoHER (7-mono-O-(β-hydroxyethyl)-rutoside) in vitro on cancer cells. Materials and Methods: HepG2 liver, MCF7 breast, and H1299 lung cancer cells were grown under ambient conditions with or without MonoHER exposure. …”
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SLC1A4 Promotes Malignant Transformation of Hepatocellular Carcinoma by Activating the AKT Signaling by Jiaoyun Zheng, Jian Gong

“…Moreover, epithelial–mesenchymal transition (EMT) in vitro and metastasis potential in vivo of hepatic cancer cells was suppressed by the downregulated SLC1A4 level. …”
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Transition Yet Energy Consuming for Tumor Growth Regulated by the Colored Microenvironment by Leiyan Chen, Yan Wang, Qingqing Li, Haohua Wang

“…., it can promote the diffusion also contribute to killing cancer cells simultaneously; (2) AT of additive noise can reduce the occurrence probability of cancer cells, but the NS can increase this probability; (3) the effect of the cross-correlated strength (CS) on cell phenotype is twofold, i.e., increasing CS may urge the mean first passage time (MFPT) of switching to the tumor state to have the minimum and maximum values but the cross-correlation time (CT) always makes the MFPT to have a minimum value. …”
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Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis by Donna M. Sosnoski, Venkatesh Krishnan, William J. Kraemer, Courtenay Dunn-Lewis, Andrea M. Mastro

“…It is commonly accepted that cancer cells interact with host cells to create a microenvironment favoring malignant colonization. …”
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Gastric Endocrine Cell Carcinoma Coexistent with Adenocarcinoma by Nobuhiro Takeuchi, Nomura Yusuke, Tetsuo Maeda, Kazuyoshi Naba

“…Pathological examination of the gross specimen revealed that adenocarcinoma comprised <10% of all cancer cells. Close analysis of ECC revealed a mixture of small and large cells. …”
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Application of Synthetic Polymeric Scaffolds in Breast Cancer 3D Tissue Cultures and Animal Tumor Models by Girdhari Rijal, Chandra Bathula, Weimin Li

“…Finally, cancer cell-laden polymeric scaffolds support consistent tumor formation in animals and biomarker expression as seen in human native tumors. …”
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Biophysical Profiling of Tumor Cell Lines by Frederick Coffman, Rachid Hamid, Marion C. Cohen, Ralph Garippa, Stanley Cohen

“…Despite significant differences in genetic profiles, cancer cells share common phenotypic properties, including membrane-associated changes that facilitate invasion and metastasis. …”
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Circadian Rhythms and Breast Cancer: The Role of Per2 in Doxorubicin-Induced Cell Death by Megan I. Mitchell, Anna-Mart Engelbrecht

“…Our results show that Per2 silencing effectively sensitizes the chemoresistant MDA-MB-231 breast cancer cells to the cytotoxic effects of doxorubicin.…”
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Anti-Proliferative Activity of Poloxamer Cobalt Ferrite Nanoparticles against Human Prostate Cancer (DU-145) Cells: In-Vitro Study by Nazanin Oroskhani, Seyed Mohammad Amini, Sakine Shirvalilou, Mehdi Khodaie, Seyed Rabi Mahdavi

“…This study refers to the novel hyperthermia application of poloxamer-coated cobalt ferrite as a new approach for thermal eradication of DU-145 human prostate cancerous cells under a radio frequency magnetic field (RF-MF). …”
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miR-21 promotes cervical cancer by regulating NTF3 by Yishan Chen, Caiwu Su, Yuke Cai, Lina Ke, Yaxiong Huang

“…This study underscores the critical role of miR-21 in regulating the proliferation, migration, and apoptosis of cervical cancer cells by targeting NTF3.…”
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Activating Mutation (V617F) in the Tyrosine Kinase JAK2 is Absent in Locally-Confined or Castration-Resistant Prostate Cancer by Lei Gu, Xian-Hua Zhu, Tapio Visakorpi, Kalle Alanen, Tuomas Mirtti, Tina Bocker Edmonston, Marja T. Nevalainen

“…Background: Transcription factor Stat5a/b is highly critical for the viability of human prostate cancer cells in vitro and for prostate tumor growth in vivo. …”
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Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

“…However, the dramatic shift in cell behaviour of the semi-adherent cells shows that cell morphology plays an important role in the responsiveness of cancer cells to AC electric fields. This study highlights the lack of understanding of the complex mechanisms by which electric fields exert effects on cancer cells. …”
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Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor by Kexin Zhang, Xudong Yang, Qi Zhao, Zugui Li, Fangmei Fu, Hao Zhang, Minying Zheng, Shiwu Zhang

“…Understanding the molecular mechanism of adipogenesis and adipose differentiation of cancer cells may contribute to cancer treatments that involve inducing differentiation into benign cells.…”
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