Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition by Andrey V. Markov, Arseny D. Moralev, Kirill V. Odarenko

“…Glioblastoma is one of the most aggressive brain cancers, characterized by active infiltrative growth and high resistance to radiotherapy and chemotherapy. …”
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Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B1-Induced Experimental Hepatocellular Carcinoma by Vijaya Ravinayagam, Ravindran Jaganathan, Sachdanandam Panchanadham, Shanthi Palanivelu

“…Hepatocellular carcinoma (HCC) is one of the most fatal cancers due to delayed diagnosis and lack of effective treatment options. …”
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Nitrile-aminothiol bioorthogonal near-infrared fluorogenic probes for ultrasensitive in vivo imaging by Weiping Xu, Shujuan Yi, Jie Liu, Yuyan Jiang, Jiaguo Huang

“…In living male mice, such ‘cleavage-click-assembly’ regimen allows for real-time and ultrasensitive detection of small cancerous lesions (~2 mm in diameter) with improved SBR (~5) and extended detection window (~36 h), outperforming conventional clinical assays. …”
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Detection of Neoplastic Gastric Lesions Using Capsule Endoscopy: Pilot Study by Byoung Yeon Jun, Chul-Hyun Lim, Wook Hyun Lee, Jin Su Kim, Jae Myung Park, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi

“…Capsule endoscopy (Pillcam ESO) was performed within 48 hours of esophagogastroduodenoscopy for eight patients who were diagnosed with gastric cancers, the size of which were less than 4 cm and who presented written consent. …”
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Sorafenib-Associated Heart Failure Complicated by Cardiogenic Shock after Treatment of Advanced Stage Hepatocellular Carcinoma: A Clinical Case Discussion by Candace Wu, Kamal Shemisa

“…As TKI usage grows for treatment of cancers, heart failure-related complications will increase. …”
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Forward programming of hPSCs to neutrophils using chemically defined media by Hayley E. Hall, Xiaoping Bao, Cheng Dong, Xiaojun Lance Lian

“…In recent years, PMNs have gained increasing recognition for their significant involvement in the pathogenesis of a wide array of human diseases, including sepsis, pulmonary conditions, autoimmune disorders, and various cancers. Due to their terminally differentiated state, PMNs possess a short lifespan and exhibit limited proliferative potential, which makes continuous replenishment from the bone marrow essential for maintaining immune homeostasis. …”
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Targeting quorum sensing for manipulation of commensal microbiota by Zachary Ziegert, Matthew Dietz, Max Hill, Marjais McBride, Elizabeth Painter, Mikael H. Elias, Christopher Staley

“…Further, we describe emerging evidence for the role of QS in non-infectious, chronic, microbially associated diseases including inflammatory bowel diseases and cancers. Finally, we describe potential therapeutic approaches that involve leveraging QS signals as well as quorum quenching approaches to block signaling in vivo to mitigate deleterious consequences to the host. …”
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The Union between Structural and Practical Identifiability Makes Strength in Reducing Oncological Model Complexity: A Case Study by Maria Pia Saccomani, Karl Thomaseth

“…A complex model to study “in vivo” antitumor activity of interleukin-21 on tumor eradication in different cancers in mice is illustrated.…”
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Gamma Knife Radiosurgery Treatment for Metastatic Melanoma of the Trigeminal Nerve and Brainstem: A Case Report and a Review of the Literature by Halloran E. Peterson, Erik W. Larson, Robert K. Fairbanks, Wayne T. Lamoreaux, Alexander R. Mackay, Jason A. Call, John J. Demakas, Barton S. Cooke, Christopher M. Lee

“…Brainstem metastases (BSMs) are uncommon but serious complications of some cancers. They cause significant neurological deficit, and options for treatment are limited. …”
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Automated Classification of Glandular Tissue by Statistical Proximity Sampling by Jimmy C. Azar, Martin Simonsson, Ewert Bengtsson, Anders Hast

“…We demonstrate the efficacy of the method in extracting discriminative features for obtaining high classification rates for tubular formation in both healthy and cancerous tissue, which is an important component in Gleason and tubule-based Elston grading. …”
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Placenta-Specific Protein 1: A Potential Key to Many Oncofetal-Placental OB/GYN Research Questions by Eric J. Devor, Henry D. Reyes, Donna A. Santillan, Mark K. Santillan, Chinenye Onukwugha, Michael J. Goodheart, Kimberly K. Leslie

“…In addition to placentae PLAC1 is expressed in a variety of solids including breast, endometrial, and ovarian cancers. In order to show that PLAC1 is potentially relevant to a number of research questions in OB/GYN, we report on PLAC1 expression in a selected panel that includes two choriocarcinoma cell lines, normal placental tissues, and endometrial and ovarian tumors. …”
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Pparg may Promote Chemosensitivity of Hypopharyngeal Squamous Cell Carcinoma by Meng Lian, Jiaming Chen, Xixi Shen, Lizhen Hou, Jugao Fang

“…The upregulation of peroxisome proliferator-activated receptor gamma (PPARG) has been shown to increase the chemosensitivity of several human cancers. This study is aimed at studying if PPARG sensitizes hypopharyngeal squamous cell carcinoma (HSCC) in chemotherapeutic treatments and at dissecting possible mechanisms of observed effects. …”
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Extracorporeal Ultrasound-Guided High Intensity Focused Ultrasound: Implications from the Present Clinical Trials by Tinghe Yu, Xiao Fu

“…The survival rate of HIFU plus radiotherapy was lower than that of radical surgery in liver cancers. Adverse events had no downtrend in the past years. …”
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Comprehensive Analysis of TSPAN32 Regulatory Networks and Their Role in Immune Cell Biology by Grazia Scuderi, Katia Mangano, Maria Cristina Petralia, Maria Sofia Basile, Francesco Di Raimondo, Paolo Fagone, Ferdinando Nicoletti

“…These findings not only shed light on the biology of TSPAN32 but also provide the basis for exploring its diagnostic, prognostic, and therapeutic potential in autoimmune and inflammatory disorders, as well as in hematopoietic cancers.…”
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Downregulation of p70S6K Enhances Cell Sensitivity to Rapamycin in Esophageal Squamous Cell Carcinoma by Zhaoming Lu, Kezheng Peng, Ning Wang, Hong-Min Liu, Guiqin Hou

“…It has been demonstrated that mTOR/p70S6K pathway was abnormally activated in many cancers and rapamycin and its analogs can restrain tumor growth through inhibiting this pathway, but some tumors including esophageal squamous cell carcinoma (ESCC) appear to be insensitive to rapamycin in recent studies. …”
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A shallow convolutional neural network for cerebral neoplasm detection from magnetic resonance imaging by Hossein Sadr, Zeinab Khodaverdian, Mojdeh Nazari, Mohammad Yamaghani

“…The effective management of cerebral carcinoma relies on early and accurate diagnosis of brain cancers. Prompt diagnosis not only helps in developing more effective treatments but also has life-saving potential. …”
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Disgerminoma puro de ovario en adolescente: presentación de un caso y revisión de la literatura by Caridad Socorro Castro, Martha María Chávez Valdivia, Javier Martínez Navarro

“…Los disgerminomas son tumores relativamente raros y constituyen alrededor del 2 % de todos los canceres ováricos, sin embargo, representan aproximadamente la mitad de los tumores malignos de células germinales. …”
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Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines by Sabran Affidah, Kumolosasi Endang, Jantan Ibrahim

“…Recent studies suggest that annexin A1 (ANXA1) promotes apoptosis in cancerous cells. This study aims to investigate the effects of ANXA1 on apoptosis and cell cycle arrest in K562, Jurkat and U937 cells and peripheral blood mononu-clear cells (PBMC). …”
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Bibliometric analysis of metformin as an immunomodulator (2013–2024) by Tongyi Zhou, Yunfeng Yu, Liu Li, Xiu Liu, Xiu Liu, Qin Xiang, Rong Yu, Rong Yu

“…These studies have mostly been published in journals such as the International Journal of Molecular Sciences, Cancers, Frontiers in Immunology, and Scientific Reports. …”
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Novel Pt (II) Complexes With Anticancer Activity Against Pancreatic Ductal Adenocarcinoma Cells by Erika Stefàno, Gianluca Rovito, Luca G. Cossa, Federica De Castro, Viviana Vergaro, Asjad Ali, Giulia My, Danilo Migoni, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive type of solid tumor that is becoming more common. cis-[PtCl2 (NH3)2] (in short cisplatin or CDDP) has been shown to be effective in treating various cancers, including PDAC. However, the development of resistance to chemotherapy drugs has created a need for the synthesis of new anticancer agents. …”
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