Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Altered function of claudins is implicated in different form of cancers, inflammatory bowel diseases (IBDs), and leaky diarrhea. …”
Get full text

NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis by Tian Tang, Feng Zeng

“…Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of head and neck cancers. In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. …”
Get full text

Multifaceted functions of the Wilms tumor 1 protein: From its expression in various malignancies to targeted therapy by Qing Nian, Yan Lin, Jinhao Zeng, Yanna Zhang, Rongxing Liu

“…This article provides information on the roles of WT1 in the pathogenesis of different cancers and provides insights into drugs and immunotherapies targeting WT1. …”
Get full text

Lipid Antigens: Revealing the Hidden Players in Adaptive Immune Responses by Tamana Eskandari, Yasamin Eivazzadeh, Fatemeh Khaleghinia, Fatemeh Kashi, Valentyn Oksenych, Dariush Haghmorad

“…These advancements have paved the way for lipid-based vaccines and immunotherapies through the application of nanoparticles and synthetic lipid antigens designed to boost immune responses against cancers and infectious diseases. Lipid trafficking, CD1 molecule interactions, and the immune system’s response to lipid antigens are yet to be completely understood, particularly in the context of autoimmunity and microbial infections. …”
Get full text

Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses by Ying Xiong, Linpeng Yao, Jinglai Lin, Jiaxi Yao, Qi Bai, Yuan Huang, Xue Zhang, Risheng Huang, Run Wang, Kang Wang, Yu Qi, Pingyi Zhu, Haoran Wang, Li Liu, Jianjun Zhou, Jianming Guo, Feng Chen, Chenchen Dai, Shuo Wang

“…Improving the diagnosis of benign renal masses and distinguishing aggressive cancers from indolent ones is key to better treatment selection. …”
Get full text

Expressions of CXCL12/CXCR4 in Oral Premalignant and Malignant Lesions by Juan Xia, Na Chen, Yun Hong, Xiaobing Chen, Xiaoan Tao, Bin Cheng, Yulei Huang

“…The chemokine receptor CXCR4 and its ligand CXCL12 have been suggested to play important roles in the initiation or progression of cancers. The goal of the present study was to investigate alterations of CXCL12/CXCR4 in oral premalignant lesions and oral squamous cell carcinoma (OSCC). …”
Get full text

The Skin-Lightening Power of Tirbanibulin 1% Ointment by Federica Li Pomi, Andrea d’Aloja, Michelangelo Rottura, Mario Vaccaro, Francesco Borgia

“…Methods We report a single-center retrospective study of patients affected by solar lentigines (SLs) and AKs in the context of field cancerization treated with tirbanibulin 1% ointment. …”
Get full text

Recent Advances, Research Trends, and Clinical Relevance of Hyaluronic Acid Applied to Wound Healing and Regeneration by Gloria Huerta-Ángeles, Edgar Mixcoha

“…The synthesis/catabolism of HA is critical in several pathologies and has been used as a marker for the prognosis of cancers. Among its physiological roles, HA is used for wound healing applications. …”
Get full text

The Effect of Edible Mushroom on Health and Their Biochemistry by Anmut Assemie, Galana Abaya

“…Therefore, edible mushrooms are herbal antibiotics to many diseases as well as various cancers of humans.…”
Get full text

True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair by Nicolas Le May, Jean-Marc Egly, Frédéric Coin

“…NER defects lead to three genetic disorders that result in predisposition to cancers, accelerated aging, neurological and developmental defects. …”
Get full text

A Western Case of Intravascular Large B-Cell Lymphoma as Unusual Cause of Persistent Fever by Pier Paolo Piccaluga, Stefania Paolini, Cristina Campidelli, Nicola Vianelli, Luigi Bolondi

“…Fever of unknown origin (FUO) is a common and challenging clinical condition that can be referred, among others, to infections, drug’s effects, various inflammatory disorders, and cancers. Among the latter, lymphomas can indeed cause fever, which is therefore accounted as a lymphoma-related sign in patients’ staging. …”
Get full text

Sarcoma primitivo de mama. Presentación de un caso by Lidia Torres Ajá

“…El sarcoma primitivo de la mama es el tumor maligno no epitelial menos frecuente, representa solamente menos del 1 % de los cánceres de la mama. Presentan un pronóstico sombrío con la presencia de metástasis tempranas, principalmente a nivel de pulmón y hueso y tienen una sobrevida muy pobre de solo 5 años. …”
Get full text

Pediatric Ovarian Growing Teratoma Syndrome by Rebecca M. Rentea, Aaron Varghese, Atif Ahmed, Alexander Kats, Michelle Manalang, Tazim Dowlut-McElroy, Richard J. Hendrickson

“…Ovarian immature teratoma is a germ cell tumor that comprises less than 1% of ovarian cancers and is treated with surgical debulking and chemotherapy depending on stage. …”
Get full text

Identification of Potential Selective PAK4 Inhibitors Through Shape and Protein Conformation Ensemble Screening and Electrostatic-Surface-Matching Optimization by Xiaoxuan Zhang, Meile Zhang, Yihao Li, Ping Deng

“…P21-activated kinase 4 (PAK4) plays a crucial role in the proliferation and metastasis of various cancers. However, developing selective PAK4 inhibitors remains challenging due to the high homology within the PAK family. …”
Get full text

SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases by Minoru Fujimoto, Tetsuji Naka

“…The studies using SOCS1-deficient mice revealed that endogenous SOCS1 is critical for the prevention of liver diseases such as hepatitis, cirrhosis, and cancers. Recent studies on humans suggest that SOCS1 is involved in the development of various liver disorders in humans. …”
Get full text

Krait2: a versatile software for microsatellite investigation, visualization and marker development by Lianming Du, Jiahao Chen, Dalin Sun, Kelei Zhao, Qianglin Zeng, Nan Yang

“…Microsatellite expansions play pivotal roles in gene expression regulation and are implicated in various neurological diseases and cancers. Although much effort has been devoted to developing efficient tools for microsatellite identification, there is still a lack of a powerful tool for large-scale microsatellite analysis. …”
Get full text

Trogocytosis-mediated immune evasion in the tumor microenvironment by Jeonghyun Kim, Soyeon Park, Jungseo Kim, Yewon Kim, Hong Min Yoon, Bima Rexa Rayhan, Jaekwang Jeong, Alfred L. M. Bothwell, Jae Hun Shin

“…This review aims to explore the trogocytosis-mediated transfer of immune regulatory molecules and their implications within the tumor microenvironment to elucidate the underlying mechanisms of immune evasion in cancers.…”
Get full text

Radiofrequency Ablation of Hepatocellular Carcinoma: A Literature Review by Yasunori Minami, Masatoshi Kudo

“…Radiofrequency ablation (RFA) of liver cancers can be performed safely using percutaneous, laparoscopic, or open surgical techniques, and much of the impetus for the use of RFA has come from cohort series that have provided an evidence base for this technique. …”
Get full text

Effect of His-Tag on Expression, Purification, and Structure of Zinc Finger Protein, ZNF191(243-368) by Dongxin Zhao, Zhongxian Huang

“…Zinc finger proteins are associated with hereditary diseases and cancers. To obtain an adequate amount of zinc finger proteins for studying their properties, structure, and functions, many protein expression systems are used. …”
Get full text

Essential functions, syntheses and detection of sialyl Lewis X on glycoproteins by Qiushi Chen, Han Liu, Xuechen Li

“…The biological importance of sLeX in fertilization and development, immunity, cancers, and other aspects will be first introduced. …”
Get full text