Synthesis and Characterization of Nickel Nanoparticles: Biological and Photocatalytic Properties by Fadliah Fadliah, Indah Raya, Ahyar Ahmad, Paulina Taba, Muhammad Burhanuddinnur, Maming Gaffar, Tri Widayati Putri, Arfiani Nur, Andi Nur Fitriani Abubakar, Rachmin Munadi, Ahmad Fudhail Majid, Irham Pratama, M. Yasser, Sulistiani Jarre, Harningsih Karim

“…Furthermore, nickel nanoparticles' cytotoxic activity demonstrates their capacity to kill cancer cells, and their photocatalytic activity demonstrates their efficiency in breaking down organic contaminants. …”
Get full text

Relationship between four healthy lifestyle factors and all-cause and cardiovascular disease mortality among residents aged 35 – 75 years in Hebei province by Yuhuan LIU, Lijuan TANG, Xiaoying LU, Jingjing ZHAO, Yajing CAO, Xiaoli LIU, Dongsheng JIANG

“…These participants had complete information on four healthy lifestyle factors (non-smoking, no or moderate alcohol consumption, adequate physical activity, and a healthy diet) and socio-economic characteristics, and no history of CVD or cancer. Mortality data were obtained by linking with the cause-of-death surveillance platform, with follow-up until December 31, 2022. …”
Get full text

Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database by Qian Qiao, Qian Qiao, Qian Qiao, Jiachen Sun, Jiachen Sun, Jiachen Sun, Ya Zheng, Ya Zheng, Yingying Mi, Yingying Mi, Yingying Mi, Yanan Gong, Yanan Gong, Jiahui Liu, Jiahui Liu, Jiahui Liu, Wenyue Rui, Wenyue Rui, Wenyue Rui, Yumei Ma, Yumei Ma, Yumei Ma, Yongning Zhou, Yongning Zhou, Min Liu, Min Liu

“…In terms of sex, the risk of cancer was higher in men compared to women in the infliximab-only and combination groups; however, no sex difference was observed in the azathioprine-only group. …”
Get full text

Molecular evidence of the inhibitory potential of melatonin against sodium arsenite toxicity by Ramtin Farhadi, Marzieh Daniali, Maryam Baeeri, Reza Khorasani, Hamed Haghi-Aminjan, Mahdi Gholami, Mahban Rahimifard, Mona Navaei-Nigjeh, Mohammad Abdollahi

“…Exposure to SA is associated with many health concerns, such as the prevalence of cancer and diabetes mellitus type 2 (DMT2). Many studies suggest that SA induces inflammation and biochemical impairments through different mechanisms, including increasing oxidative stress and altering vital genes such as biochemical and anti-inflammatory. …”
Get full text

PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…BackgroundTransplant recipients face increased cancer mortality due to immunosuppressive treatments. …”
Get full text

Polygonatum kingianum polysaccharide alleviated intestinal injuries by mediating antioxidant ability and microbiota by Reng Qiu, Chuangye Pan, Yuxi Qin, Qianfei Wei, Yue Yu, Ying Zhang, Xuehan Xie, Jianqin Li, Shouhai Chen, Kun Li, Dalia Fouad, Yi Wu, Qiu Zhong

“…IntroductionPolygonatum kingianum is a well-known medicinal herb with proven bioactivities; however, little is known about the effects of its polysaccharide on intestinal injuries in animals induced by lipopolysaccharide (LPS).MethodsA total of 30 Institute of Cancer Research (ICR) mice were divided into control (CH), induced (MH), and treated (H) groups. …”
Get full text

Regional hyperthermia for soft tissue sarcoma – a survey on current practice, controversies and consensus among 12 European centers by Siyer Roohani, Felix Ehret, Marcus Beck, Danai P. Veltsista, Jacek Nadobny, Sebastian Zschaeck, Sultan Abdel-Rahman, Franziska Eckert, Anne Flörcken, Rolf D. Issels, Stephan Klöck, Robert Krempien, Lars H. Lindner, Markus Notter, Oliver J. Ott, Daniel Pink, Vlatko Potkrajcic, Peter Reichardt, Oliver Riesterer, Mateusz Jacek Spałek, Emanuel Stutz, Rüdiger Wessalowski, Thomas Zilli, Daniel Zips, Pirus Ghadjar, David Kaul

“…Purpose To analyze the current practice of regional hyperthermia (RHT) for soft tissue sarcoma (STS) at 12 European centers to provide an overview, find consensuses and identify controversies necessary for future guidelines and clinical trials.Methods In this cross-sectional survey study, a 27-item questionnaire assessing clinical subjects and procedural details on RHT for STS was distributed to 12 European cancer centers for RHT.Results We have identified seven controversies and five consensus points. …”
Get full text

Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro... by Valeria Cento, Sara Carloni, Riccardo Sarti, Linda Bussini, Zian Asif, Paola Morelli, Francesco De Fazio, Federica Maria Tordato, Maddalena Casana, Debora Mondatore, Antonio Desai, Elena Generali, Nicola Pugliese, Elena Costantini, Massimo Vanoni, Maurizio Cecconi, Stefano Aliberti, Giorgio Da Rin, Erminia Casari, Michele Bartoletti, Antonio Voza

“…Clinical features included age, sex, comorbidities (e.g., cancer, diabetes), infection source, presence of central venous catheters (CVC), ongoing therapies, and sepsis severity. …”
Get full text

A Cardiac‐Targeting and Anchoring Bimetallic Cluster Nanozyme Alleviates Chemotherapy‐Induced Cardiac Ferroptosis and PANoptosis by Junyue Xing, Xiaohan Ma, Yanan Yu, Yangfan Xiao, Lu Chen, Weining Yuan, Yingying Wang, Keyu Liu, Zhiping Guo, Hao Tang, Kelong Fan, Wei Jiang

“…This study presents a promising avenue for preventing chemotherapy‐induced cardiotoxicity, offering potential clinical benefits for cancer patients.…”
Get full text

Human hair biochar to remove malachite green dye and bisphenol-A contamination by M. Kamaraj, P. Kamali, R. Kaviya, K. Abishek, B. Navinkumar, T.G. Nithya, L.S. Wong, J. Aravind

“…BACKGROUND AND OBJECTIVES: Exposure to endocrine-disrupting chemicals and organic dye pollution is associated with an increased risk of toxicity, hazard, and cancer due to their widespread use. Exogenous endocrine disruptors are responsible for interfering with reproduction and development because they can either stimulate or decrease endogenous hormone responses. …”
Get full text

Indoor, outdoor, and personal exposure to PM2.5 and associated health risk in community-dwelling elderly residents in Fuzhou city, 2021: a cross-sectional study by Shuling KANG, Xin LIN, Kan LIN, Baoying LIU, Chuancheng WU, Jianjun XIANG, Jingwen CHEN, Quan ZHOU

“…Exposure to PAHs in PM2.5 posed a potential carcinogenic risk to the participants, with excess lifetime cancer risks (ELCRs) of 12.74 × 10 – 6 and 1.673 × 10 – 6 for winter and summer exposure, respectively. …”
Get full text

Acute kidney injury is associated with liver-related outcomes in patients with hepatitis B virus infection: a retrospective cohort study by Jiao Liu, Ruixuan Chen, Shiyu Zhou, Zhixin Guo, Licong Su, Lisha Cao, Yanqin Li, Xiaodong Zhang, Fan Luo, Ruqi Xu, Qi Gao, Yuxin Lin, Xin Xu, Sheng Nie, the CRDS study Investigators

“…Results Of the 86,204 inpatients with HBV infection and without liver cancer or cirrhosis at baseline, 4407(5.1%) patients experienced AKI. …”
Get full text

Functional Improvement Trajectories After Surgery (FIT After Surgery) study: protocol for a multicentre prospective cohort study to evaluate significant new disability after major... by E Jacobsohn, Duminda N Wijeysundera, Gerald Lebovic, M Davis, Martine T E Puts, Shabbir M H Alibhai, Karim S Ladha, C Wong, Daniel I McIsaac, C Hanley, T Barnes, G Lorello, N Siddiqui, P Serrano, Tyler R Chesney, S Choi, J Van Vlymen, D Sussman, D Macdonald, P Jüni, Emily Hladkowicz, C David Mazer, M Bosch, CD Mazer, A Jerath, J Pazmino-Canizares, E Kennedy, R Spence, V Lyon, Alice C Wei, Julian F Daza, Sahar Ehtesham, Janet M van Vlymen, DN Wijeysundera, KS Ladha, JF Daza, G Mattina, E Hladkowicz, M Tessier, S Ehtesham, S Nnorom, SMH Alibhai, M Puts, G Lebovic, TR Chesney, AC Wei, S Drozdz, M Louridas, RH Breau, M Lalu, S Abdellatif, S Gagne, E Duceppe, K Zarnke, D Dumerton, M Karizhenskaia, H El Beheiry, F Bonazza, A Zahavich, M Thorleifson, S L Russell, H Bagry, SY MacDonell, J Dale-Gandar, L Kaustov, A Fleet, E Al Azazi, M Parotto, S A McCluskey, H Poonawala, D Dillane, Di McIsaac, S Avramescu, S Shabeen

Get full text

Pomacea canaliculata hemocyanin as a novel natural immunostimulant in mammals by Ignacio Rafael Chiumiento, Ignacio Rafael Chiumiento, María Alejandra Tricerri, María Alejandra Tricerri, María Fernanda Cortéz, Santiago Ituarte, Santiago Ituarte, Julia Tau, Karina Valeria Mariño, Paola Lorena Smaldini, Horacio Heras, Horacio Heras, Marcos Sebastián Dreon, Marcos Sebastián Dreon

“…While the hemocyanin from the marine snail keyhole limpet (KLH), has been widely studied and successfully employed as a carrier/adjuvant in several immunological applications, as well as a non-specific immunostimulant for bladder cancer treatment, few other gastropod hemocyanins have been biochemically and immunologically characterized. …”
Get full text

Post-acute sequelae of hospitalised COVID-19 re-infection compared with hospitalised first-time infection: a population-based retrospective cohort study in Hong Kong by Yin Zhang, Francisco T T Lai, Shirley Chiu Wai Chan, Chak Sing Lau, Xue Li, Eric Yuk Fai Wan, Lung Yi Mak, Celine S L Chui, Ivan F N Hung, Esther Wai Yin Chan, Vincent Ka Chun Yan, Deliang Yang, Carlos Wong, Ian Chi-Kei Wong

Get full text

Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments by Bowen Yin, Jingyi Ren, Xuanyi Liu, Yadong Zhang, Jinshi Zuo, Rui Wen, Huanting Pei, Miaomiao Lu, Siqi Zhu, Zhenao Zhang, Ziyi Wang, Yanyi Zhai, Yuxia Ma

“…BackgroundDoxorubicin (DOX), a widely employed chemotherapeutic agent in cancer treatment, has seen restricted use in recent years owing to its associated cardiotoxicity. …”
Get full text

Stimulation of TLR4 by LMW-HA Induces Metastasis in Human Papillary Thyroid Carcinoma through CXCR7 by Shipeng Dang, Yongde Peng, Lei Ye, Yanan Wang, Zhongqing Qian, Yuqing Chen, Xiaojing Wang, Yunzhi Lin, Xiaomei Zhang, Xiyan Sun, Qiong Wu, Yiji Cheng, Hong Nie, Min Jin, Huanbai Xu

Get full text

Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…IntroductionThe global health challenge of ulcerative colitis (UC) has been classified by the WHO as a modern refractory disease, commonly referred to as green cancer, with limited treatment options still available, highlighting the urgent need for the development of new therapeutic strategies. …”
Get full text

Impact of Immune Checkpoint Inhibitors and Local Radical Treatment on Survival Outcomes in Synchronous Oligometastatic NSCLC by Mandy Jongbloed, MD, Valentina Bartolomeo, MD, Martina Bortolot, MD, Shahan Darwesh, MD, Jarno W.J. Huijs, MD, Safiye Dursun, MD, Juliette Degens, MD, PhD, Ben E.E.M. van den Borne, MD, PhD, Maggy Youssef-El Soud, MD, PhD, Marcel Westenend, MD, PhD, Cordula Pitz, MD, PhD, Dirk K.M. De Ruysscher, MD, PhD, Lizza E.L. Hendriks, MD, PhD

“…Methods: Multicenter retrospective study including adequately staged patients, with sOMD NSCLC (maximum five metastases in three organs [European Organization for Research and Treatment of Cancer definition]) between January 1, 2015 and December 31, 2022, treated with a first-line ICI-based versus chemotherapy-only regimen. …”
Get full text

Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway by Yihan Lai, Yihan Lai, Mingkang Li, Mingkang Li, Juan Zhan, Juan Zhan, Lin Jiang, Lin Jiang, Yuan Wu, Zhiyi Fang, Jianhan Zhou, Jianhan Zhou, Yujie Ma, Yisen Shao, Yisen Shao, Wei Wang, Wei Wang

“…Studies have shown that Brucea javanica oil (BJO) extracts have anti-cancer effects against a variety of cancers, but little research has been reported on OSCC. …”
Get full text